LEADER 02496nam 2200697z- 450 001 9910557665403321 005 20220111 035 $a(CKB)5400000000044852 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/76275 035 $a(oapen)doab76275 035 $a(EXLCZ)995400000000044852 100 $a20202201d2021 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aThe Immunology and Biology of Brain Tumors 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021 215 $a1 online resource (88 p.) 311 08$a3-0365-0102-9 311 08$a3-0365-0103-7 330 $aImmunotherapy has become a viable treatment modality for a variety of cancers (and referred to as Science Magazine's "Breakthrough of the Year" in 2013, as well as ASCO's "Advance of the Year" in both 2016 and 2017). 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Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact 606 $aNeurosciences$2bicssc 606 $aScience: general issues$2bicssc 610 $aaction potential (AP) 610 $aaxonal dynamics 610 $aimaging 610 $apatch-clamp 610 $asynaptic release 615 7$aNeurosciences 615 7$aScience: general issues 700 $aKawaguchi$b Shin-ya$4edt$01331395 702 $aTrigo$b Federico F$4edt 702 $aKawaguchi$b Shin-ya$4oth 702 $aTrigo$b Federico F$4oth 906 $aBOOK 912 $a9910557520903321 996 $aControl of Presynaptic Function by Axonal Dynamics$93040367 997 $aUNINA LEADER 05097nam 2201201z- 450 001 9910637782803321 005 20221206 010 $a3-0365-5822-5 035 $a(CKB)5470000001631709 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/94587 035 $a(oapen)doab94587 035 $a(EXLCZ)995470000001631709 100 $a20202212d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMarine Glycomics 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 online resource (208 p.) 311 08$a3-0365-5821-7 330 $aMarine creatures are rich sources of glycoconjugate-containing glycans and have diversified structures. The advance of genomics has provided a valuable clue for their production and developments. This information will encourage breeding and engineering functional polysaccharides with slime ingredients in algae. These glycans will have the potential for applications to antioxidant, anticancer, and antimicrobial drugs in addition to health supplements and cosmetics. The combination of both biochemical and transcriptome approaches of marine creatures will lead to the opportunity to discover new activities of proteins such as glycan-relating enzymes and lectins. These proteins will also be used for experimental and medical purposes, such as diagnostics and trial studies. The topic of marine glycomics is also focusing on understanding the physiological properties of marine creatures, such as body defense against pathogens and cancers. In the competitions for natural selection, living creatures have evolved both their glycans and their recognition. They have primitive systems of immunity, and few of their mechanisms are closely related to glycans. If we are able to describe the accumulation of data of glycans of creatures living in the seashore and the oceans, we may be able to anticipate a time when we can talk about the ecosystem with glycans. 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