LEADER 03090nam  2200589z- 450 
001 9910637780503321
005 20231214133151.0
010   $a3-0365-5616-8
035   $a(CKB)5470000001631732
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/94545
035   $a(EXLCZ)995470000001631732
100   $a20202212d2022      |y             0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aQuantitative PET and SPECT
210   $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022
215   $a1 electronic resource (212 p.)
311   $a3-0365-5615-X 
330   $aSince the introduction of personalized medicine, the primary focus of imaging has moved from detection and diagnosis to tissue characterization, the determination of prognosis, prediction of treatment efficacy, and measurement of treatment response. Precision (personalized) imaging heavily relies on the use of hybrid technologies and quantitative imaging biomarkers. The growing number of promising theragnostics require accurate quantification for pre- and post-treatment dosimetry. Furthermore, quantification is required in the pharmacokinetic analysis of new tracers and drugs and in the assessment of drug resistance. Positron Emission Tomography (PET) is, by nature, a quantitative imaging tool, relating the time?activity concentration in tissues and the basic functional parameters governing the biological processes being studied. Recent innovations in single photon emission computed tomography (SPECT) reconstruction techniques have allowed for SPECT to move from relative/semi-quantitative measures to absolute quantification. The strength of PET and SPECT is that they permit whole-body molecular imaging in a noninvasive way, evaluating multiple disease sites. Furthermore, serial scanning can be performed, allowing for the measurement of functional changes over time during therapeutic interventions. This Special Issue highlights the hot topics on quantitative PET and SPECT.
606   $aMedicine$2bicssc
606   $aClinical & internal medicine$2bicssc
610   $aPET
610   $aSPECT
610   $aPET/CT
610   $aSPECT/CT
610   $aAbsolute quantification
610   $aQuantitative accuracy
610   $aDynamic PET
610   $aPhantoms
610   $aRepeatability
610   $aTumor delineation
610   $aPrognosis
610   $aDosimetry
610   $aRadiomics
610   $aArtificial intelligence
610   $aDeep learning
610   $aImaging biomarkers
610   $aTumor segmentation
610   $aHarmonization
615  7$aMedicine
615  7$aClinical & internal medicine
700   $ade Geus-Oei$b Lioe-Fee$4edt$01283368
702   $avan Velden$b Floris H. P$4edt
702   $ade Geus-Oei$b Lioe-Fee$4oth
702   $avan Velden$b Floris H. P$4oth
906   $aBOOK
912   $a9910637780503321
996   $aQuantitative PET and SPECT$93019123
997   $aUNINA