LEADER 03869nam 22006615 450 001 9910635385103321 005 20251009072057.0 010 $a981-19-7327-X 024 7 $a10.1007/978-981-19-7327-7 035 $a(MiAaPQ)EBC7158293 035 $a(Au-PeEL)EBL7158293 035 $a(CKB)25732566900041 035 $a(DE-He213)978-981-19-7327-7 035 $a(OCoLC)1355851491 035 $a(EXLCZ)9925732566900041 100 $a20221216d2023 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aBrain-Iron Cross Talk /$fedited by Wael Mohamed, Nicola Luigi Brogazzi, Richard M. Kostrzewa 205 $a1st ed. 2023. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2023. 215 $a1 online resource (289 pages) 225 1 $aNutritional Neurosciences,$x2730-6720 311 08$aPrint version: Mohamed, Wael Brain-Iron Cross Talk Singapore : Springer,c2023 9789811973260 320 $aIncludes bibliographical references and index. 327 $aPART I. Iron, Brain Function and Behavior -- Chapter 1. Iron and Neuro-cognition -- Chapter 2. The Interplay Between Iron and Oxidative Stress in Brain Neurodegenerative Diseases -- Chapter 3. Specific Nutritional Therapeutic Approaches Targeting Iron Overload and Other Hallmarks of Brain Degenerative Diseases -- Chapter 4. Mediterranean Diet and Neuro-Cognition: Focus on Alzheimer disease -- PART II Brain disorders related to Iron -- Chapter 5. The Critical Roleplay of Iron Neurochemistry in Progression of Parkinson?s Disease -- Chapter 6. Iron-Calcium Crosstalk in Neurodegenerative Diseases -- Chapter 7. Iron and Alzheimer?s Disease -- Chapter 8. Iron and Multiple Sclerosis -- Chapter 9. Iron and Epilepsy -- Chapter 10. Iron and Subarachnoid Hemorrhage -- Chapter 11. Iron deficiency and psychiatric disorders -- Chapter 12. Iron and Neuro-developmental Disorders -- Chapter 13. Iron and Neuropathies. 330 $aThis book explores the molecular mechanisms of iron hemostasis in the brain and discusses the cognitive and behavioral implications of iron deficiency. It presents the effect of iron dysregulation on neurophysiological mechanisms. The book provides an overview of iron metabolism and homeostasis at the cellular level and its regulation at the mRNA translation level. It emphasizes the importance of iron for brain development in fetal and early life in preterm infants. Further, it presents iron metabolism as a therapeutic target for novel pharmacological treatment against neurodevelopmental diseases and neurodegenerative disorders. It discusses the role of iron deficiency in sleep disorders and offers diagnosis and treatment of iron-related CNS diseases. Finally, it relates dysregulated expression of iron-related genes in brain tumors. 410 0$aNutritional Neurosciences,$x2730-6720 606 $aNeurosciences 606 $aNervous system$xDiseases 606 $aDevelopmental neurobiology 606 $aCognitive neuroscience 606 $aNeuroscience 606 $aNeurological Disorders 606 $aDevelopment of the Nervous System 606 $aCognitive Neuroscience 615 0$aNeurosciences. 615 0$aNervous system$xDiseases. 615 0$aDevelopmental neurobiology. 615 0$aCognitive neuroscience. 615 14$aNeuroscience. 615 24$aNeurological Disorders. 615 24$aDevelopment of the Nervous System. 615 24$aCognitive Neuroscience. 676 $a599.0188 702 $aBrogazzi$b Nicola Luigi 702 $aKostrzewa$b Richard M. 702 $aMohamed$b Wael 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910635385103321 996 $aBrain-iron cross talk$93089758 997 $aUNINA