LEADER 03230nam 2200397 450 001 9910633979303321 005 20230323195100.0 010 $a1-80355-055-4 035 $a(CKB)5700000000338567 035 $a(NjHacI)995700000000338567 035 $a(EXLCZ)995700000000338567 100 $a20230323d2022 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aExtracellular Vesicles $eRole in Diseases, Pathogenesis and Therapy /$fedited by Manash K. Paul 210 1$aLondon :$cIntechOpen,$d2022. 215 $a1 online resource (338 pages) 225 1 $aPhysiology 311 $a1-80355-054-6 327 $a1. Introductory Chapter: Role of Extracellular Vesicles in Human Diseases and Therapy -- 2. Mechanisms of Extracellular Vesicle Biogenesis, Cargo Loading, and Release -- 3. Extracellular Vesicles and Their Interplay with Biological Membranes -- 4. Morphology and Formation Mechanisms of Cellular Vesicles Harvested from Blood -- 5. High-Throughput Single Extracellular Vesicle Profiling -- 6. Extracellular Vesicles as Intercellular Communication Vehicles in Regenerative Medicine -- 7. Roles of Extracellular Vesicles in Human Reproduction -- 8. Exosomes and HIV-1 Association in AIDS-Defining Patients -- 9. The Role of Extracellular Vesicles in Immunomodulation and Pathogenesis of Leishmania and Other Protozoan Infections -- 10. Retracted: The Role of Extracellular Vesicles in the Progression of Tumors towards Metastasis -- 11. Exosomes in Cancer Diagnosis and Radiation Therapy -- 12. Diversity of Extracellular Vesicles (EV) in Plasma of Cancer Patients -- 13. Extracellular Vesicles as Biomarkers and Therapeutic Targets in Cancers -- 14. Extracellular Vesicles and Ovarian Cancer -- 15. Engineering of Extracellular Vesicles as Nano Therapy for Breast Cancer -- 16. Roles of Extracellular Vesicles in Cancer Metastasis -- 17. Tumor-Derived Exosome and Immune Modulation -- 18. Extracellular Vesicles for Cancer Immunotherapy: Biomarkers and Beyond. 330 $aExtracellular vesicles (EVs) are nanoscale vesicles secreted by cells that mediate horizontal cargo transport from donor to recipient cell, thereby establishing cell-cell communication and signaling. This book provides critical information on the fundamentals of EVs, their roles in diseases like cancer, and their use in disease management. The chapters emphasize the emerging data confirming the role of EVs in the pathogenesis of diseases and discuss the scientific advances that have made it feasible to characterize and engineer EVs, leading to their use as tools in biomarker discovery and disease diagnosis, prognosis, therapeutic application, and theranostics. This volume is a valuable resource for basic biologists, translational scientists, and clinicians. 410 0$aEBE biology program.$nUnit 4,$pPhysiology. 517 $aExtracellular Vesicles 606 $aLiposomes 615 0$aLiposomes. 676 $a571.655 702 $aPaul$b Manash K. 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910633979303321 996 $aExtracellular vesicles$91765275 997 $aUNINA