LEADER 03384nam 2200601 450 001 9910627285103321 005 20230803221204.0 010 $a1-78639-528-2 010 $a1-78924-374-2 010 $a1-78064-256-3 035 $a(CKB)2550000001263109 035 $a(EBL)1664152 035 $a(SSID)ssj0001181172 035 $a(PQKBManifestationID)11681196 035 $a(PQKBTitleCode)TC0001181172 035 $a(PQKBWorkID)11144880 035 $a(PQKB)11401065 035 $a(MiAaPQ)EBC1664152 035 $a(EXLCZ)992550000001263109 100 $a20140414h20142014 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aBacterial pili $estructure, synthesis and role in disease /$fedited by Miche?le A. Barocchi and John L. Telford ; contributors Edward N. Baker [and nine others] ; Rachel Cutts, commissioning editor ; Emma McCann, editorial assistant 210 1$aWallingford, England ;$aBoston, Massachusetts :$cCABI,$d2014. 210 4$dİ2014 215 $a1 online resource (220 p.) 225 1 $aAdvances in molecular and cellular microbiology ;$v27 300 $aIncludes index. 311 $a1-78064-255-5 311 $a1-306-58218-0 327 $aContents; Contributors; Foreword; 1 The Vibrio cholerae Toxin Coregulated Pilus: Structure, Assembly and Function with Implications for Vaccine Design; 2 Conjugative Pili; 3 Pilus Biogenesis by the Chaperone-Usher Pathway; 4 Type 1 and P Pili of Uropathogenic Escherichia coli; 5 Type IV Pili: Functions and Biogenesis; 6 The Pseudomonas aeruginosa Type IV Pilus Assembly System in Three Dimensions; 7 Corynebacterium diphtheriae Pili: Assembly, Structure and Function; 8 Three-dimensional Structures of Pilin Subunits and their Role in Gram-positive Pilus Assembly and Stability 327 $a9 Sortase Structure and Specificity in Streptococci10 Pili of Streptococcus pyogenes; 11 The Role of Pili in the Formation of Biofilm and Bacterial Communities; 12 Fimbriae/Pili from Oral Bacteria; 13 Pilus-based Vaccine Development in Streptococci: Variability, Diversity and Immunological Responses; Index; A; B; C; D; E; F; G; H; I; L; M; N; O; P; R; S; T; U; V; Y 330 $aBacterial pili play important roles as environmental sensors, in host colonization and in biofilm formation, enabling bacteria to interact with the environment, with surfaces and with other bacteria and host cells. Most bacteria, both Gram positive and Gram negative, and almost all bacterial pathogens, are piliated. This book discusses the synthesis, structure, evolution, function and role in pathogenesis of these complex structures, and their basis for vaccine development and therapeutics for Streptococcus pathogens. It is an invaluable resource for researchers and students of medical microbi 410 0$aAdvances in molecular and cellular microbiology ;$v27. 606 $aPili (Microbiology) 615 0$aPili (Microbiology) 676 $a579.26 702 $aBarocchi$b Miche?le A. 702 $aTelford$b John L. 702 $aBaker$b Edward N. 702 $aCutts$b Rachel 702 $aMcCann$b Emma 712 02$aC.A.B. International, 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910627285103321 996 $aBacterial pili$92978901 997 $aUNINA