LEADER 05255nam 2201465z- 450 001 9910619470903321 005 20221025 010 $a3-0365-5357-6 035 $a(CKB)5670000000391565 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/93226 035 $a(oapen)doab93226 035 $a(EXLCZ)995670000000391565 100 $a20202210d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aPig Genomics and Genetics 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 online resource (318 p.) 311 08$a3-0365-5358-4 330 $aIn this Special Issue, we present the state of the art in the field of pig genetics and genomics, including the identification of gene candidates linked to important pig traits and to nutritional modifications, with the aim of collecting the most recent advances. The published manuscripts focused on high-throughput methodologies, such as RNA sequencing, ATAC-seq, MACE-seq, chip-seq, and RRBS, and covered other fields of pig genetics. The pig (Sus scrofa) is the most common large mammal in the world. The Sus genus includes domestic pig and wild boar. Since the draft reference genome sequence of S. scrofa was assembled in 2012, the processes of identification of genes related to important phenotypic traits and of search of genetic markers for pig selection have been significantly refined. In addition, the newest wide-range high-throughput techniques, including microarrays, next-generation sequencing, and the recent PacBio sequencing platform providing ultra-long sequencing reads, allow identifying gene mutations and gene candidates throughout the whole genome, transcriptome, or epigenome and estimating quantitative traits important for breeding as well as the genetic backgrounds of inherited diseases. 606 $aBiology, life sciences$2bicssc 606 $aResearch and information: general$2bicssc 606 $aZoology and animal sciences$2bicssc 610 $a3'quant mRNA-seq 610 $aadipogenesis 610 $aalternative splicing 610 $aantimicrobial peptide 610 $aantiviral response 610 $aAQP3 610 $acircRNAs 610 $acoagulation system dysregulation 610 $acongenital defects 610 $aCRISPR/Cas9 610 $aCRISPR/Cas9 system 610 $adisease models 610 $adisease-resistant animals 610 $aDNA methylation 610 $aDNMT3B 610 $adomain 610 $aDuroc 610 $aDuroc pigs 610 $aendometrium 610 $aextracellular matrix 610 $afat deposition 610 $afatness 610 $afatty acids 610 $agene expression 610 $agenetic engineering 610 $agenetically modified pigs 610 $agenome modifications 610 $aglobal gene expression 610 $agrowth traits 610 $aGWAS (Genome-Wide Association Studies) 610 $aheat stress 610 $aHezuo Tibetan pig 610 $aHMOX1 gene 610 $ahypothalamus 610 $aIFN-? 610 $aintramuscular fat 610 $aisoform 610 $alipid metabolism 610 $alitter size 610 $alncRNA 610 $alymphatic system 610 $ameat quality 610 $ametabolic diseases 610 $ametabolome 610 $amicroarray 610 $an/a 610 $aNGS 610 $aNMR 610 $anon-homologous DNA ends joining (NHEJ) 610 $anutrigenomics 610 $aobesity 610 $aoff-target 610 $apig 610 $apigs 610 $apoly (I:C) 610 $aporcine alveolar macrophages 610 $aporcine ?-defensin 2 610 $aprecision medicine 610 $aproliferation 610 $apromoter 610 $aprotein 610 $aPRRSV 610 $apubertal genes 610 $apuberty 610 $arecombinant proteins 610 $aRNA-seq 610 $aRNA-Seq 610 $aseminal plasma 610 $asingle nucleotide polymorphism 610 $askeletal muscle fiber 610 $aSNP 610 $aSNP (single nucleotide polymorphism) 610 $aSNP array genotyping 610 $aSus scrofa 610 $aswine 610 $aTIDE analysis 610 $aTNF-? 610 $atotal number born alive 610 $atranscript 610 $atranscriptional regulation 610 $atranscriptomics 610 $atransgenic pigs 610 $aTRIM26 610 $aVSV 610 $aweighted single-step GWAS 610 $awhole-genome sequencing 610 $axenoantigen 610 $axenotransplantation 615 7$aBiology, life sciences 615 7$aResearch and information: general 615 7$aZoology and animal sciences 700 $aPio?rkowska$b Katarzyna$4edt$01291908 702 $aRopka-Molik$b Katarzyna$4edt 702 $aPio?rkowska$b Katarzyna$4oth 702 $aRopka-Molik$b Katarzyna$4oth 906 $aBOOK 912 $a9910619470903321 996 $aPig Genomics and Genetics$93022066 997 $aUNINA