LEADER 03400nam 2200877z- 450 001 9910619464403321 005 20231214133025.0 010 $a3-0365-5130-1 035 $a(CKB)5670000000391630 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/93232 035 $a(EXLCZ)995670000000391630 100 $a20202210d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aEchinoderms Metabolites: Structure, Functions and Biomedical Perspectives II 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 electronic resource (192 p.) 311 $a3-0365-5129-8 330 $aThe book largely reflect the structural diversity of echinoderm metabolites including triterpene glycosides and fucosylated chondroitin sulfates, as well as branched fatty acids, di- and triacylglycerols and other lipid classes from the sea cucumbers, polyhydroxysteroids from starfish and different classes of sphingolipids from sea cucumbers and starfish. Finally, the MS-based metabolomic approach, which is very helpful for the estimation of such diversity, is discussed. The materials from the Special Issue also illustrate the biomedical potential of the presented metabolites as cytotoxins and anticoagulants. The in silico approach broadens the possibilities to investigate the mechanisms of the action of membranolytic compounds. 517 $aEchinoderms Metabolites 606 $aResearch & information: general$2bicssc 606 $aChemistry$2bicssc 610 $adiacylglycerol ether 610 $a1-O-alkylglyceryl ether 610 $anutraceutical oils 610 $abêche-de-mer 610 $asea cucumber 610 $aBohadschia argus 610 $aHolothuria (Theelothuria) spinifera 610 $afucosylated chondroitinsulfates 610 $afucan sulfates 610 $aanticoagulant activity 610 $adisulfated steroids 610 $aNMR spectra 610 $astarfish 610 $aPteraster marsippus 610 $acytotoxic activity 610 $a3D culture 610 $aPsolus chitonoides 610 $atriterpene glycosides 610 $achitonoidosides 610 $a  triterpene glycosides 610 $amembranolytic action 610 $ahemolytic 610 $amolecular dynamic simulation 610 $aThyonidium kurilensis 610 $akurilosides 610 $apolyhydroxysteroids 610 $asteroid glycosides 610 $alipids 610 $amass spectrometry 610 $ametabolomics 610 $ametabolomic profiling 610 $asphingolipids 610 $aceramides 610 $acerebrosides 610 $agangliosides 610 $asialic acid 610 $aAsteroidea 610 $aHolothuroidea 610 $abiological activity 610 $aneuritogenic activity 610 $a  615 7$aResearch & information: general 615 7$aChemistry 700 $aKalinin$b Vladimir I$4edt$01327009 702 $aSilchenko$b Alexanra S$4edt 702 $aKalinin$b Vladimir I$4oth 702 $aSilchenko$b Alexanra S$4oth 906 $aBOOK 912 $a9910619464403321 996 $aEchinoderms Metabolites: Structure, Functions and Biomedical Perspectives II$93038943 997 $aUNINA