LEADER 03629nam 22007815 450 001 9910619286203321 005 20240429141601.0 010 $a9789811955952$b(electronic bk.) 010 $z9789811955945 024 7 $a10.1007/978-981-19-5595-2 035 $a(MiAaPQ)EBC7119922 035 $a(Au-PeEL)EBL7119922 035 $a(CKB)25179647300041 035 $a(OCoLC)1348480851 035 $a(DE-He213)978-981-19-5595-2 035 $a(PPN)265863155 035 $a(EXLCZ)9925179647300041 100 $a20221019d2022 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPlasmacytoid Dendritic Cells$b[electronic resource] /$fby Dipyaman Ganguly 205 $a1st ed. 2022. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2022. 215 $a1 online resource (170 pages) 311 08$aPrint version: Ganguly, Dipyaman Plasmacytoid Dendritic Cells Singapore : Springer,c2022 9789811955945 320 $aIncludes bibliographical references. 327 $aChapter 1_Dendritic cells and the basic principles of immune functions -- Chapter 2_Discovery of a new dendritic cell -- Chapter 3_Hematopoietic origins of plasmacytoid dendritic cells -- Chapter 4_Molecular regulation of plasmacytoid dendritic cell identity -- Chapter 5_Type I interferon production by plasmacytoid dendritic cells -- Chapter 6_Tolerogenic functions of plasmacytoid dendritic cells -- Chapter 7_Plasmacytoid dendritic cells and infections -- Chapter 8_Plasmacytoid dendritic cells in autoimmunity and allergy -- Chapter 9_Plasmacytoid dendritic cells and metabolic disorders -- Chapter 10_ Plasmacytoid dendritic cells and cancer -- Chapter 11_Therapeutic targeting of plasmacytoid dendritic cells -- Chapter 12_Experimental methodology for plasmacytoid dendritic cells. 330 $aThis book provides a systematic review of the development, function, and patho-physiologic role of plasmacytoid dendritic cells (pDCs) in humans. The chapters of the book discuss the origin and discovery, hematopoietic development as well as molecular regulation of pDCs in the context of immune activation as well as immune tolerance. It also discusses the role of pDCs in human diseases, including infections, autoimmune/inflammatory diseases, cancers and metabolic disorders, and opportunities for pDC?targeting therapies in these varied clinical contexts. . 606 $aImmunology 606 $aCancer 606 $aNatural immunity 606 $aImmunologic diseases 606 $aAutoimmunity 606 $aInflammation 606 $aImmunology 606 $aCancers 606 $aInnate Immunity 606 $aImmunological Disorders 606 $aAutoimmunity 606 $aInflammation 606 $aCèl·lules dendrítiques$2thub 606 $aImmunologia$2thub 608 $aLlibres electrònics$2thub 615 0$aImmunology. 615 0$aCancer. 615 0$aNatural immunity. 615 0$aImmunologic diseases. 615 0$aAutoimmunity. 615 0$aInflammation. 615 14$aImmunology. 615 24$aCancers. 615 24$aInnate Immunity. 615 24$aImmunological Disorders. 615 24$aAutoimmunity. 615 24$aInflammation. 615 7$aCèl·lules dendrítiques 615 7$aImmunologia 676 $a616.079 700 $aGanguly$b Dipyaman$01262830 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 912 $a9910619286203321 996 $aPlasmacytoid Dendritic Cells$92954780 997 $aUNINA