LEADER 04729nam 22006255 450 001 9910619277703321 005 20251009094105.0 010 $a3-031-08491-8 024 7 $a10.1007/978-3-031-08491-1 035 $a(MiAaPQ)EBC7119423 035 $a(Au-PeEL)EBL7119423 035 $a(CKB)25176346800041 035 $a(PPN)265856353 035 $a(DE-He213)978-3-031-08491-1 035 $a(OCoLC)1348374582 035 $a(EXLCZ)9925176346800041 100 $a20221018d2022 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPseudomonas aeruginosa $eBiology, Pathogenesis and Control Strategies /$fedited by Alain Filloux, Juan-Luis Ramos 205 $a1st ed. 2022. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2022. 215 $a1 online resource (452 pages) 225 1 $aAdvances in Experimental Medicine and Biology,$x2214-8019 ;$v1386 311 08$aPrint version: Filloux, Alain Pseudomonas Aeruginosa Cham : Springer International Publishing AG,c2022 9783031084904 320 $aIncludes bibliographical references. 327 $aPart I. Biology and Evolution of Pseudomonas aeruginosa -- Pseudomonas aeruginosa Pangenome: Core and Accessory Genes of a Highly Resourceful Opportunistic Pathogen -- Iron Homeostasis in Pseudomonas aeruginosa: Targeting Iron Acquisition and Storage as an Antimicrobial Strategy -- Controlling Biofilm Development Through Cyclic di-GMP Signaling -- Pseudomonas aeruginosa Quorum Sensing -- Antibiotic Resistance in Pseudomonas -- Part II. Cell Envelope and Secretion Systems -- Cell Envelope Stress Response in Pseudomonas aeruginosa -- Flagella, Chemotaxis and Surface Sensing -- Antimicrobial Weapons of Pseudomonas aeruginosa -- Pseudomonas aeruginosa Antivirulence Strategies: Targeting the Type III Secretion -- Part III. Pathogenesis and Virulence -- What Makes Pseudomonas aeruginosa a Pathogen? -- Transcriptional Profiling of Pseudomonas aeruginosa Infections -- Molecular Mechanisms Involved in Pseudomonas aeruginosa Bacteremia -- Pseudomonas aeruginosa in the Cystic Fibrosis Lung -- Role of Two Component System Networks in Pseudomonas aeruginosa Pathogenesis -- Mixed Populations and Co-Infection: Pseudomonas aeruginosa and Staphylococcus aureus -- How to Manage Pseudomonas aeruginosa Infections. 330 $aThis book covers the wide set of well-regulated virulence factors and defense mechanisms of Pseudomonas aeruginosa focusing on stress responses and the evolution of this opportunistic human pathogen. Pseudomonas aeruginosa is responsible for one out of ten hospital infections. Additionally, this Gram-negative bacterium is accountable for persistent infections in immunocompromised individuals and the leading cause of chronic lung infections in cystic fibrosis patients. This book provides insight on the metabolic versatility of Pseudomonas aeruginosa and its mechanisms for biofilm formation that make this organism highly efficient in causing infections. The book invites the readers to learn more about the intrinsic ability of Pseudomonas aeruginosa to resist a wide variety of antimicrobial agents due to the concerted action of multidrug efflux pumps, antibiotic-degrading enzymes, and the low permeability of bacterial cellular envelopes. Particular focus is put on the evolutionary role of different types of protein-secretion systems in pathogenesis, flagella and their role in chemotaxis and surface sensing, and host-pathogen interactions. This book is a useful introduction to the field for junior scientists interested in the biology and pathogenesis of Pseudomonas aeruginosa. It is also an interesting read for advanced scientists and medical specialists working within this field, providing a broader view of the topic beyond their specific area of specialization. 410 0$aAdvances in Experimental Medicine and Biology,$x2214-8019 ;$v1386 606 $aMicrobiology 606 $aMedical microbiology 606 $aDiseases$xCauses and theories of causation 606 $aMicrobiology 606 $aMedical Microbiology 606 $aPathogenesis 615 0$aMicrobiology. 615 0$aMedical microbiology. 615 0$aDiseases$xCauses and theories of causation. 615 14$aMicrobiology. 615 24$aMedical Microbiology. 615 24$aPathogenesis. 676 $a616.0145 676 $a579.332 702 $aFilloux$b Alain 702 $aRamos$b Juan Luis 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910619277703321 996 $aPseudomonas aeruginosa$92955174 997 $aUNINA