LEADER 04859nam 22007575 450 001 9910616380603321 005 20240403114342.0 010 $a981-19-5125-X 024 7 $a10.1007/978-981-19-5125-1 035 $a(MiAaPQ)EBC7107646 035 $a(Au-PeEL)EBL7107646 035 $a(CKB)24996000000041 035 $a(DE-He213)978-981-19-5125-1 035 $a(PPN)265862744 035 $a(EXLCZ)9924996000000041 100 $a20221005d2022 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aHerb-Drug Combinations$b[electronic resource] $eA New Complementary Therapeutic Strategy /$fby Shanmugam Hemaiswarya, Pranav Kumar Prabhakar, Mukesh Doble 205 $a1st ed. 2022. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2022. 215 $a1 online resource (285 pages) 311 08$aPrint version: Hemaiswarya, Shanmugam Herb-Drug Combinations Singapore : Springer,c2022 9789811951244 327 $aChapter 1. Introduction -- Chapter 2. Measuring Herb-drug interaction and Synergy -- Chapter 3. Herb-Herb and Food-drug interactions -- Chapter 4. Pharmacokinetic interactions in synergistic herb-drug combinations -- Chapter 5. Antagonistic Herb-drug interactions -- Chapter 6. Synergistic Herb-drug interactions against bacteria -- Chapter 7. Synergistic herb-drug interactions against tuberculosis -- Chapter 8. Synergistic herb-drug interactions against viral diseases -- Chapter 9. Synergistic herb interactions with cardiovascular drugs -- Chapter 10. Synergistic herb interactions with anticancer drugs -- Chapter 11. Synergistic herb interactions with antidiabetic drugs -- Chapter 12. Synergistic herb-drug interactions against obesity -- Chapter 13. Synergistic Herb-Drug Interactions in Neurological Disorders -- Chapter 14. Synergistic Herb-drug interactions with antifungal and antiparasitic agents -- Chapter 15. Computational methods to study herb-drug interactions -- Chapter 16. Regulations and guidelines involving synergistic plant-drug interactions -- Chapter 17. Clinical trials on synergistic herb-drug interactions -- Chapter 18. QFuture prospects on synergistic herb-drug interactions -- Chapter 19. Conclusion. 330 $aPlant extracts or their pure natural constituents have been used traditionally for thousands of years for treating diseases with considerable success in India and other Asian countries. In addition, they have also been used as complements or supplements with conventional medicine. This book discusses the latest research in the application of combination therapy, namely herbs and drugs, in the treatment of a range of communicable and non-communicable diseases to achieve a synergistic effect. This synergy may help in reducing the amount of drug, its toxicity, side effects, and development of resistance as well as improve its efficacy. The book also discusses the pharmacodynamic and pharmacokinetic parameters, experimental tools to determine the impact of combination, computational approaches to identify synergy, statistical analysis of data, and clinical and regulatory issues. The book is useful for researchers in the fields of pharmacology, pharmacy and medicinal chemistry and those working in pharmaceutical and nutraceutical industries. This book could open up new strategies to focus on multiple targets to combat complex diseases unlike the single targeted drugs that are being currently marketed by the pharmaceuticals industries. 606 $aPharmacology 606 $aPharmacy 606 $aAlternative medicine 606 $aPharmacovigilance 606 $aMedicinal chemistry 606 $aPharmacology 606 $aPharmacy 606 $aComplementary and Alternative Medicine 606 $aDrug Safety and Pharmacovigilance 606 $aMedicinal Chemistry 606 $aPlantes medicinals$2thub 606 $aMedicina alternativa$2thub 606 $aFarmacologia$2thub 608 $aLlibres electrònics$2thub 615 0$aPharmacology. 615 0$aPharmacy. 615 0$aAlternative medicine. 615 0$aPharmacovigilance. 615 0$aMedicinal chemistry. 615 14$aPharmacology. 615 24$aPharmacy. 615 24$aComplementary and Alternative Medicine. 615 24$aDrug Safety and Pharmacovigilance. 615 24$aMedicinal Chemistry. 615 7$aPlantes medicinals 615 7$aMedicina alternativa 615 7$aFarmacologia 676 $a016.61378 700 $aHemaiswarya$b Shanmugam$01261319 702 $aKumar Prabhakar$b Pranav 702 $aDoble$b Mukesh 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910616380603321 996 $aHerb-drug combinations$93048924 997 $aUNINA