LEADER 04347nam 22007455 450 001 9910595451103321 005 20251113185513.0 010 $a3-031-06858-0 024 7 $a10.1007/978-3-031-06858-4 035 $a(MiAaPQ)EBC7100661 035 $a(Au-PeEL)EBL7100661 035 $a(CKB)24950006800041 035 $a(PPN)26496022X 035 $a(OCoLC)1346127842 035 $a(DE-He213)978-3-031-06858-4 035 $a(EXLCZ)9924950006800041 100 $a20220924d2022 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aOptical Whispering Gallery Modes for Biosensing $eFrom Physical Principles to Applications /$fby Frank Vollmer, Deshui Yu 205 $a2nd ed. 2022. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2022. 215 $a1 online resource (489 pages) 225 1 $aPhysics and Astronomy Series 311 08$aPrint version: Vollmer, Frank Optical Whispering Gallery Modes for Biosensing Cham : Springer International Publishing AG,c2022 9783031068577 320 $aIncludes bibliographical references and index. 327 $aSensing with Light -- Surface Plasmon Resonance -- Whispering Gallery Modes in Optical Microcavities -- Applications of WGM Microcavities in Physics -- Single Molecule Sensing -- Fundamentals of Quantum Optics -- Molecular cavity QED. 330 $aThis interdisciplinary book covers the fundamentals of optical whispering gallery mode (WGM) microcavities, light?matter interaction, and biomolecular structure with a focus on applications in biosensing. Novel biosensors based on the hybridization of WGM microcavities and localized surface plasmon resonances (LSPRs) in metal nanoparticles have emerged as the most sensitive microsystem biodetection technology that boasts single molecule detection capability without the need for amplification and labeling of the analyte. The book provides an ample survey of the physical mechanisms of WGMs and LSPRs for detecting affinity, concentration, size, shape and orientation of biomarkers, while informing the reader about different classes of biomolecules, their optical properties and their importance in label-free clinical diagnostics. This expanded and updated second edition features a new chapter that introduces the reader to advanced in vivo biosensing techniques using WGM microcavities, looking at photothermal sensing, methods for trapping neutral atoms around WGM microcavities, and practical aspects of optoplasmonic sensing. The second Edition now provides a comprehensive introduction to the use of WGM microcavities in physical sensing which includes measurements with frequency combs, macro and micro (one atom) lasers, gyroscopes, optomechanical and parity-time-symmetric sensor devices. Chapter-end problems round out this comprehensive and fundamental textbook, inspiring a host of up-and-coming physicists, bioengineers, and medical professionals to make their own breakthroughs in this blossoming new field. This textbook can be used for both introductory and advanced courses about the modern optics of optical microcavities. 410 0$aPhysics and Astronomy Series 606 $aBiophysics 606 $aMaterials 606 $aDetectors 606 $aBiomedical engineering 606 $aPharmaceutical chemistry 606 $aNanobiotechnology 606 $aBiophysics 606 $aSensors and biosensors 606 $aBiomedical Engineering and Bioengineering 606 $aMedicinal Chemistry 606 $aNanobiotechnology 615 0$aBiophysics. 615 0$aMaterials. 615 0$aDetectors. 615 0$aBiomedical engineering. 615 0$aPharmaceutical chemistry. 615 0$aNanobiotechnology. 615 14$aBiophysics. 615 24$aSensors and biosensors. 615 24$aBiomedical Engineering and Bioengineering. 615 24$aMedicinal Chemistry. 615 24$aNanobiotechnology. 676 $a610.28 676 $a610.28 700 $aVollmer$b Frank$0843496 702 $aYu$b Deshui 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910595451103321 996 $aOptical whispering gallery modes for biosensing$92255290 997 $aUNINA