LEADER 00855nam a2200229 i 4500 001 991002204489707536 005 20020503162342.0 008 961027s1969 it ||| | ita 035 $ab10331074-39ule_inst 035 $aEXGIL99986$9ExL 040 $aBiblioteca Interfacoltà$bita 100 1 $aMarchesi, Luigi$0466870 245 10$aCome siamo arrivati a Brindisi /$cLuigi Marchesi 260 $aMilano :$bV. Bompiani v,$c1969 300 $a196 p. ;$c22 cm. 650 4$aGuerra mondiale 1939-1945$zItalia$y1943 - Diari e memorie 907 $a.b10331074$b02-04-14$c27-06-02 912 $a991002204489707536 945 $aLE002 Fondo Berg. 911$g1$iLE002-73700$lle002$o-$pE0.00$q-$rn$so $t0$u0$v0$w0$x0$y.i10389301$z27-06-02 996 $aCome siamo arrivati a Brindisi$9199840 997 $aUNISALENTO 998 $ale002$b01-01-96$cm$da $e-$fita$git $h0$i1 LEADER 02728nam 2200361z- 450 001 9910595095703321 005 20251017110116.0 035 $a(CKB)5670000000388188 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/92534 035 $a(DNLM)9918486469206676 035 $a(EXLCZ)995670000000388188 100 $a20202209d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aBreast Cancer 210 $aBrisbane, Australia$cExon Publications$d2022 215 $a1 electronic resource (234 p.) 311 08$a0-645-33203-8 330 $aBreast cancer has become the most diagnosed cancer globally, surpassing lung and prostate cancers. In 2020, 2.3 million females were diagnosed with breast cancer worldwide. The incidence and related mortality from breast cancer continue to grow despite remarkable advances in our understanding of the biology of breast cancer and the availability of better therapeutic options. Therapies currently used to treat metastatic breast cancer extend the survival and quality of life of patients, but they are not curative. Therefore, a better understanding of the mechanisms involved in metastatic dissemination is of pivotal importance. This book provides a unique blend of carefully presented and structured information covering a broad array of relevant breast cancer-related issues. The first eight chapters cover breast cancer epidemiology, etiology, subtypes, current and emerging surgical innovations to treat and image breast cancer, a description of noninvasive lymphedema assessment methods to detect and track this important treatment complication, and the potential role of platelets and galectins in breast cancer metastasis. The last five chapters are devoted to the description of forward-looking albeit potential breast cancer treatment possibilities. In this regard, different chapters of the book describe novel research on the potential of ubiquitin-specific protease 18 (USP-18), ribosomal protein S6 kinase 1 (RPS6K1), the lysosomal system, nanoparticles, and proteolysis target chimeras as therapeutic agents for breast cancer. The range of clinical and translational research of breast cancer presented in this book will be of interest to healthcare professionals, clinicians, and basic scientists. 606 $aBreast Neoplasms 606 $aMJCL$2bicssc 610 $abreast cancer 615 2$aBreast Neoplasms. 615 7$aMJCL 700 $aMayrovitz$b Harvey N$4edt$01322453 702 $aMayrovitz$b Harvey N$4oth 906 $aBOOK 912 $a9910595095703321 996 $aBreast Cancer$93035024 997 $aUNINA