LEADER 06971nam 2202161z- 450 001 9910595071903321 005 20231214132837.0 035 $a(CKB)5680000000080810 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/92038 035 $a(EXLCZ)995680000000080810 100 $a20202209d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMarine Drug Research in China: Selected Papers from the 15-NASMD Conference 210 $aBasel$cMDPI Books$d2022 215 $a1 electronic resource (512 p.) 311 $a3-0365-4569-7 311 $a3-0365-4570-0 330 $aThe Book covers this whole field, from the discovery of structurally new and bioactive natural products (including biomacromolecules), from marine macro-/micro-organisms, to the pharmacodynamics, pharmacokinetics, metabolisms, and mechanisms of marine-derived lead compounds, both in vitro and in vivo, along with the synthesis and/or structural optimization of marine-derived lead compounds and their structure?activity relationships. Taken together, this Special Issue reprint not only provides inspiration for the discovery of marine-derived novel bioactive compounds, but also sheds light on the further research and development of marine candidate drugs. 517 $aMarine Drug Research in China 606 $aMedicine$2bicssc 610 $aAntarctic krill (Euphausia superba) 610 $apeptide 610 $aantioxidant activity 610 $astability 610 $aoyster 610 $aplasma 610 $apeptidome 610 $aantimicrobial peptides 610 $acytotoxicity 610 $aactinomycete 610 $apiericidins 610 $aabsolute configuration 610 $aPestalotiopsis heterocornis 610 $aheterocornols 610 $aanti-inflammatory activity 610 $asponge-derived fungus 610 $asclerotides 610 $alipodepsipeptide 610 $aAspergillus sclerotiorum 610 $anasopharyngeal carcinoma 610 $aAChE inhibitory 610 $avascular endothelial cell 610 $aflavonoid 610 $aoxidized low-density lipoprotein 610 $aNrf2 610 $aapoptosis 610 $abutyrolactone I 610 $afood allergy 610 $ametabolism 610 $apharmacokinetics 610 $aactinomycin X2 610 $amicrobial pigments 610 $adyeing 610 $asilk 610 $aantibacterial properties 610 $aPD-L1 610 $avirtual screening 610 $apharmacophore modeling 610 $aADME 610 $amolecular dynamics 610 $axanthones 610 $aascidian-derived fungus 610 $aDiaporthe sp. 610 $aanti-glioma activity 610 $aantiaging 610 $aSonneratia apetala 610 $asignaling pathway 610 $aCaenorhabditis elegans 610 $amutants 610 $acoral-derived fungi 610 $aAspergillus hiratsukae 610 $ameroterpenoids 610 $aantibacterial activity 610 $acytotoxic activity 610 $adeep-sea-derived fungus 610 $aAspergillus puniceus 610 $aisoquinoline alkaloid 610 $aprotein tyrosine phosphatase inhibitor 610 $aantibacterial 610 $aAspergillus sp. 610 $ageodin 610 $asemisynthesize 610 $ainsecticidal activity 610 $aArca inflata 610 $aantitumor peptide 610 $aMAPK signaling 610 $acalmodulin 610 $acolorectal cancer 610 $amethicillin-resistant Staphylococcus aureus 610 $aactinomycin D 610 $aStreptomyces parvulus 610 $amechanism 610 $amangrove endophytic Pestalotiopsis 610 $aSdy-1 610 $aantitumor activity 610 $aWnt signaling 610 $a?-catenin 610 $aeremophilane sesquiterpenoids 610 $amangrove-derived fungus 610 $aPenicillium sp. 610 $aOceanapia 610 $asponge 610 $asecondary metabolites 610 $abiological activities 610 $adrug design 610 $aanticancer 610 $acyclic pentapeptide 610 $agalaxamide analogues 610 $askipjack tuna (Katsuwonus pelamis) muscle 610 $aangiotensin-I-converting enzyme (ACE) peptide 610 $amolecular docking 610 $anitric oxide (NO) 610 $aendothelin-1 (ET-1) 610 $aTrichoderma longibrachiatum 610 $asesquiterpene glycoside 610 $aantimicrobial activity 610 $amarine fungi 610 $aAspergillus unguis 610 $adepsides 610 $adepsidones 610 $aosteoclast differentiation 610 $asoft-coral-derived fungus 610 $apyranodipyran derivatives 610 $atyrosyl DNA phosphodiesterase 1 inhibitory activities 610 $afluorescent properties 610 $abutenolides 610 $aenantiomers 610 $aAspergillus terreus 610 $apancreatic lipase 610 $aNAFLD 610 $afucoxanthin 610 $aadenosine monophosphate-activated protein kinase (AMPK) 610 $anuclear factor erythroid-2-related factor 2-mediated (Nrf2) 610 $aToll-like receptor 4-mediated (TLR4) 610 $aAspergillus flavipes HN4-13 610 $aemodin 610 $amacroporous resin XAD-16 610 $aadsorption kinetics and isotherms 610 $aenrichment 610 $atetramic acid derivatives 610 $adeep-sea fungus 610 $aclavipitacae 610 $aLecanicillium fusisporum 610 $achronic kidney disease 610 $afucoidan 610 $acognitive dysfunction 610 $aneuroinflammation 610 $aoxidative stress 610 $aGSK3?-Nrf2-HO-1 signaling 610 $amicroglial polarization 610 $adeep-sea actinomycetes 610 $aaromatic acids 610 $aoximes 610 $aantihyperlipidemic 610 $aphycocyanin 610 $amicrobiota 610 $atranscriptome 610 $aIL-17 pathway 610 $aHahella 610 $aprodiginine 610 $achejuenlide 610 $agenome mining 610 $aLC-MS/MS 610 $aCDK4/6 610 $amarine compounds 610 $apharmacophore construction 610 $aADMET 610 $amm-pbsa 615 7$aMedicine 700 $aZhou$b Xuefeng$4edt$0845353 702 $aLuo$b Xiaowei$4edt 702 $aLiu$b Yonghong$4edt 702 $aZhou$b Xuefeng$4oth 702 $aLuo$b Xiaowei$4oth 702 $aLiu$b Yonghong$4oth 906 $aBOOK 912 $a9910595071903321 996 $aMarine Drug Research in China: Selected Papers from the 15-NASMD Conference$93014644 997 $aUNINA