LEADER 02277nam 2200721z- 450 001 9910595069503321 005 20231214133108.0 035 $a(CKB)5680000000080836 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/92087 035 $a(EXLCZ)995680000000080836 100 $a20202209d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aHallmarks of Parkinson?s Disease 210 $aBasel$cMDPI Books$d2022 215 $a1 electronic resource (124 p.) 311 $a3-0365-5015-1 311 $a3-0365-5016-X 330 $aThis book gathers a collection of review articles aiming to provide an update of the current knowledge on PD pathogenesis. It notably includes an overview of several key cellular dysfunctions underlying the etiology of Parkinson?s disease, including ER stress, mitophagy and alpha-synuclein-linked pathology. 606 $aMedicine$2bicssc 606 $aNeurosciences$2bicssc 610 $aParkinson?s disease 610 $aunfolded protein response 610 $areticulum endoplasmic 610 $agenetics 610 $aalpha-synuclein 610 $aprion-like spreading 610 $acell-to-cell transfer 610 $aneurodegeneration 610 $amitochondrial dysfunction 610 $aPINK1 610 $aneurons 610 $aastrocytes 610 $amicroglia 610 $a?-synuclein 610 $aexocytosis 610 $alipids 610 $amembranes 610 $aParkinson disease 610 $aSNARE complex 610 $asynapse 610 $avesicle fusion 610 $atherapeutic target 610 $aprotein quality control 610 $amitochondrial quality control 610 $aubiquitin 610 $aalpha-syn 610 $amitophagy 610 $aParkin 610 $amito-Keima 610 $amito-QC 610 $amito-SRAI 615 7$aMedicine 615 7$aNeurosciences 700 $aAlves Da Costa$b Cristine$4edt$01332308 702 $aAlves Da Costa$b Cristine$4oth 906 $aBOOK 912 $a9910595069503321 996 $aHallmarks of Parkinson?s Disease$93040810 997 $aUNINA