LEADER 10591nam 2200505 450 001 9910595048103321 005 20231110211541.0 010 $a3-031-08220-6 035 $a(MiAaPQ)EBC7098188 035 $a(Au-PeEL)EBL7098188 035 $a(CKB)24865886700041 035 $a(PPN)264955870 035 $a(EXLCZ)9924865886700041 100 $a20230220d2022 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aClinical cases in leprosy /$fSwetalina Pradhan and Piyush Kumar 210 1$aCham, Switzerland :$cSpringer International Publishing,$d[2022] 210 4$d©2022 215 $a1 online resource (271 pages) 225 1 $aClinical Cases in Dermatology 311 08$aPrint version: Pradhan, Swetalina Clinical Cases in Leprosy Cham : Springer International Publishing AG,c2022 9783031082191 327 $aIntro -- Preface -- Acknowledgements -- Contents -- Contributors -- Part I: Basics -- Chapter 1: Clinical Classification of Leprosy -- Introduction -- Classification of Leprosy -- Criteria Deciding Classifications -- Types -- Ridley-Jopling Classification [1, 2] -- Indian Classification [4] -- New IAL Classification [5] -- WHO Classification (1988) -- WHO Classification (1998) [6] -- Current WHO Classification -- Classification Under NLEP, India (2009) [8] -- Conclusion -- References -- Chapter 2: Clinical Examination -- Introduction -- Clinical Examination -- General Examination -- Cutaneous Examination -- Number of Skin Lesions -- The Distribution of Skin Lesions -- Examination of Individual Skin Lesion -- Morphology -- Size -- Shape -- Margin/Edge of Skin Lesions -- Satellite Lesions -- Color of Lesion -- Surface -- Tenderness -- Anesthesia -- Examination of Peripheral Nerves -- Examination of Musculoskeletal System -- Motor Examination -- Muscle Strength Grading in Peripheral Centers -- Mucosal Examination -- Nasal Mucosa Examination -- Oral Mucosa Examination -- Ocular Examination -- Test for Lagophthalmos -- External Genital Examination -- Other Systemic Examination -- Conclusion -- References -- Chapter 3: Microbiological Investigations and Histopathology -- Introduction -- Slit Skin Smear (SSS) [1, 2] -- Histopathology -- Tuberculoid Leprosy (TT) -- Borderline Tuberculoid Leprosy -- Borderline Leprosy -- Borderline Lepromatous Leprosy -- Lepromatous Leprosy -- Indeterminate Leprosy -- Histoid Leprosy -- Pure Neural Leprosy -- Type 1 Reaction -- Upgrading Reaction -- Downgrading Reaction -- Type 2 Reaction (Erythema Nodosum Leprosum) -- Resolution [8] -- References -- Chapter 4: Electrophysiological and Radiological Investigations -- Introduction -- Electrophysiological Studies -- Nerve Conduction Study (NCS) -- Principles. 327 $aInterpretation -- NCS and Leprosy -- Electromyography (EMG) -- Principles -- Interpretation -- EMG and Leprosy -- Radiologic Examination -- Radiography of the Hands, Feet, and Face -- Hands and Feet -- Face -- High-Resolution Ultrasonography (HRUS) -- Principles -- Parameters Assessed -- Interpretation -- Magnetic Resonance Imaging -- Principles -- Interpretation -- Conclusion -- References -- Chapter 5: Serological and Molecular Investigations in Leprosy -- Introduction -- Overview -- Diagnosis of Leprosy -- Serological Investigations -- Phenolic Glycolipid-1 (PGL-1) -- 35kD Protein -- M. Leprae Recombinant Proteins and Development of LID-1 and NDO-LID Rapid Test -- IgA Antibody-Based Test -- Cytokines/Chemokines as Biomarker in Leprosy -- Gene-Based Assays -- M. Leprae-Specific PCR -- Multiplex PCR (M-PCR) -- In Silico Molecular Techniques -- Loop-Mediated Isothermal Amplification (LAMP) Assay -- Conclusion -- References -- Chapter 6: Treatment of Leprosy and Lepra Reactions -- Introduction -- Historical Regimes -- Dapsone Monotherapy -- Rifampicin Monotherapy -- WHO MDT (WHO Multidrug Therapy) -- The WHO FD-MDT Regimen [14] -- Alternate Regimens (Non-WHO MDT) -- Newer MDT Regimens -- MB Cases -- PB Cases -- Accompanied MDT [20] -- Uniform MDT [21] -- Resistance to MDT -- Defaulter -- Relapse -- Treatment of Lepra Reaction -- Childhood Leprosy -- Leprosy and Pregnancy -- Leprosy and Tuberculosis -- Leprosy and Human Immunodeficiency Virus (HIV) -- Non-acceptance to Clofazimine -- Dapsone Toxicity -- Hepatosafe Regimen -- References -- Chapter 7: Counselling in Leprosy -- Introduction -- The Burden of Stigma and Mental Illness in Leprosy Affected -- What Does Counselling Mean -- Objectives of Counselling -- Counselling in Leprosy -- Interventions in Counselling -- References -- Chapter 8: Physical Rehabilitation in Leprosy -- Introduction. 327 $aComponents of Physical Rehabilitation -- Assessment of Nerve Damage -- Primary and Secondary Impairments in Leprosy Due to Nerve Damage -- Eye-Hand-Feet (EHF) Scoring -- Occupational Therapy -- Prevention of the Progression of Impairment -- Exercises -- Splints -- Self-Care of Anesthetic Parts -- Ulcer Management -- Surgical Rehabilitation -- Nerve Surgery -- Reconstructive Surgery -- References -- Chapter 9: Community Rehabilitation in Leprosy -- Introduction -- The Holistic Rehabilitation -- Case Study from India -- Social Support from Self-Help Groups and in the Form of Microcredits -- Case Study from India -- Case Study from Odisha -- Way Forward -- References -- Part II: Case Studies -- Chapter 10: Annular Erythematous Plaque on the Face in a Lady -- Clinical Presentation -- What Is Your Diagnosis? -- Investigations -- Final Diagnosis -- Discussion -- References -- Chapter 11: 27-Year-Old Male with Hypopigmented Patch on the Left Thigh -- Clinical Presentation -- What Is the Diagnosis? -- Investigations -- Final Diagnosis -- Discussion -- References -- Chapter 12: Erythematous Plaque on the Lower Face -- Clinical Presentation -- What Is Your Diagnosis? -- Investigations -- Final Diagnosis -- Discussion -- References -- Chapter 13: Annular Erythematous Plaque on the Right Hand -- Clinical Presentation -- What Is Your Diagnosis? -- Investigation -- Final Diagnosis -- Discussion -- Conclusion -- References -- Chapter 14: A 50-Year-Old Male with Multiple Hypopigmented Macules and Patches -- Clinical Presentation -- What Is Your Diagnosis? -- Investigations -- Final Diagnosis -- Discussion -- References -- Chapter 15: Multiple Asymptomatic Nodules on the Body -- Clinical Presentation -- What Is Your Diagnosis? -- Investigations -- Final Diagnosis: Lepromatous Leprosy -- Discussion -- References -- Chapter 16: Skin-Coloured Nodules and Atrophic Scars. 327 $aClinical Presentation -- What Is Your Diagnosis? -- Investigation -- Final Diagnosis -- Discussion -- References -- Chapter 17: 70-Year-Old Male with Nodules over Frictional Areas -- Clinical Presentation -- What Is Your Diagnosis? -- Investigation -- Final Diagnosis -- Discussion -- References -- Chapter 18: A-30-Year-Old Male with Left Foot Drop -- Clinical Presentation -- What Is Your Diagnosis? -- Investigations -- Final Diagnosis -- Discussion -- References -- Chapter 19: Asymptomatic Papules and Nodules Over the Body -- Clinical Presentation -- What Is Your Diagnosis? -- Investigations -- Final Diagnosis -- Discussion -- References -- Chapter 20: An Asymptomatic Swelling on the Right Arm -- Clinical Presentation -- What Is Your Diagnosis? -- Investigations -- Final Diagnosis -- Discussion -- References -- Chapter 21: A Female with Erythematous Plaques Over the Face and Trunk -- Clinical Presentation -- What Is Your Diagnosis? -- Investigations -- Final Diagnosis -- Discussion -- References -- Chapter 22: Erythematous Plaques over Photo Exposed Areas -- Clinical Presentation -- What Is Your Diagnosis? -- Investigations -- Final Diagnosis -- Discussion -- References -- Chapter 23: Painful Nodules and Cribriform Scars on the Body -- Clinical Presentation -- What Is Your Diagnosis? -- Investigations -- Final Diagnosis -- Discussion -- References -- Chapter 24: Generalized Painful Erythematous Nodules -- Clinical Presentation -- What Is Your Diagnosis? -- Investigations -- Final Diagnosis -- Discussion -- References -- Chapter 25: Sudden Onset Painful Ulcers in an Adult Female -- Clinical Presentation -- What Is Your Diagnosis? -- Investigation -- Final Diagnosis -- Discussion -- References -- Chapter 26: Multiple Annular Plaques -- Clinical Presentation -- What Is Your Diagnosis? -- Investigations -- Final Diagnosis -- Discussion -- References. 327 $aChapter 27: Non-healing Ulcer on the Sole -- Clinical Presentation -- What Is Your Diagnosis? -- Investigations -- Final Diagnosis -- Discussion -- References -- Chapter 28: 40-Year-Old Male with Claw Hand -- Clinical Presentation -- What Is Your Diagnosis? -- Investigations -- Final Diagnosis -- Discussion -- References -- Chapter 29: A 55-Year-Old Male with Foot Drop and Claw Toes -- Clinical Presentation -- What Is Your Diagnosis? -- Investigations -- Final Diagnosis -- Discussion -- References -- Chapter 30: A 60-Year-Old Female with Corneal Opacity -- Clinical Presentation -- What Is Your Diagnosis? -- Investigations -- Final Diagnosis -- Discussion -- References -- Chapter 31: Reticulate Purpura and Painful Ulcers -- Clinical Presentation -- What Is Your Diagnosis? -- Investigations -- Final Diagnosis -- Discussion -- References -- Chapter 32: Asymptomatic Finger Swelling -- Clinical Presentation -- What Is Your Diagnosis? -- Investigations -- Final Diagnosis -- Discussion -- References -- Chapter 33: Generalized Erythematous Edematous Plaques and Nodules -- Clinical Presentation -- What Is Your Diagnosis? -- Investigations -- Final Diagnosis -- Discussion -- References -- Chapter 34: Generalized Pustulo-Ulcerative Lesions -- Clinical Presentation -- What Is Your Diagnosis? -- Investigations -- Final Diagnosis -- Discussion -- References -- Chapter 35: Acral Nodules in an Elderly Male -- Clinical Presentation -- What Is Your Diagnosis? -- Investigations -- Final Diagnosis -- Discussion -- References -- Index. 410 0$aClinical Cases in Dermatology 606 $aLeprosy 606 $aLeprosy$xPrevention 615 0$aLeprosy. 615 0$aLeprosy$xPrevention. 676 $a616.998 700 $aPradhan$b Swetalina$01258383 702 $aKumar$b Piyush 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910595048103321 996 $aClinical cases in leprosy$93039149 997 $aUNINA