LEADER 04113nam 22006855 450 001 9910588598903321 005 20251225203650.0 010 $a9783031150340 010 $a3031150341 024 7 $a10.1007/978-3-031-15034-0 035 $a(MiAaPQ)EBC7075920 035 $a(Au-PeEL)EBL7075920 035 $a(CKB)24720951800041 035 $a(PPN)264191463 035 $a(BIP)85411827 035 $a(BIP)85092964 035 $a(DE-He213)978-3-031-15034-0 035 $a(EXLCZ)9924720951800041 100 $a20220818d2022 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aComputational Methods in Systems Biology $e20th International Conference, CMSB 2022, Bucharest, Romania, September 14?16, 2022, Proceedings /$fedited by Ion Petre, Andrei P?un 205 $a1st ed. 2022. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2022. 215 $a1 online resource (324 pages) 225 1 $aLecture Notes in Bioinformatics,$x2366-6331 ;$v13447 311 08$aPrint version: Petre, Ion Computational Methods in Systems Biology Cham : Springer International Publishing AG,c2022 9783031150333 327 $aChemical Reaction Networks Algebraic Biochemistry: a Framework for On-line Analog Computation in Cells -- Abstract Simulation of Reaction Networks via Boolean Networks -- Abstraction-Based Segmental Simulation of Chemical Reaction Networks -- Qualitative dynamics of chemical reaction networks: an investigation using partial tropical equilibrations -- Boolean Networks Prioritization of candidate genes through Boolean networks -- Variable Stabilisation in Boolean Monotonic Model Pools -- Variable-Depth Simulation of Most Permissive Boolean Networks -- Minimal trap spaces of Logical models are maximal siphons of their Petri net encoding -- Continuous and Hybrid Models Stability versus Metastability in a Model of Skin Fages Exact linear reduction for rational dynamical systems -- Limit cycle analysis of a class of hybrid gene regulatory networks -- Machine Learning Bayesian learning of effective chemical master equations in crowded intracellular conditions -- Probabilistic Multivariate Early WarningSignals -- A Meta-Species Language for Chemical Reaction Networks -- Automated Generation of Conditional Moment Equations for Stochastic Reaction Networks -- An Extension of ERODE to Reduce Boolean Networks by Backward Boolean Equivalence -- 2.0: Modelling and Analysis of Regulated Rule-based Systems. 330 $aThis book constitutes the refereed proceedings of the 20th International Conference on Computational Methods in Systems Biology, CMSB 2022, held in Bucharest, Romania, in September 2022. The 13 full papers and 4 tool papers were carefully reviewed and selected from 43 submissions. CMSB focuses on modeling, simulation, analysis, design and control of biological systems. The papers are arranged thematically as follows: Chemical reaction networks; Boolean networks; continuous and hybrid models; machine learning; software. 410 0$aLecture Notes in Bioinformatics,$x2366-6331 ;$v13447 606 $aBioinformatics 606 $aComputer systems 606 $aArtificial intelligence 606 $aBiological models 606 $aComputational and Systems Biology 606 $aComputer System Implementation 606 $aArtificial Intelligence 606 $aBiological Models 615 0$aBioinformatics. 615 0$aComputer systems. 615 0$aArtificial intelligence. 615 0$aBiological models. 615 14$aComputational and Systems Biology. 615 24$aComputer System Implementation. 615 24$aArtificial Intelligence. 615 24$aBiological Models. 676 $a570.285 676 $a570.285 702 $aPetre$b Ion 702 $aPa?un$b Andrei 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910588598903321 996 $aComputational Methods in Systems Biology$92907803 997 $aUNINA