LEADER 04845nam 22004692 450 001 9910585962803321 005 20200207154548.0 010 $a1-108-57502-1 010 $a1-108-57663-X 010 $a1-108-61670-4 035 $a(CKB)4100000010077151 035 $a(UkCbUP)CR9781108616706 035 $a(MiAaPQ)EBC6184504 035 $a(Au-PeEL)EBL6184504 035 $a(OCoLC)1155250757 035 $a(EXLCZ)994100000010077151 100 $a20180604d2019|||| uy| 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPhilosophy of immunology /$fThomas Pradeu$b[electronic resource] 210 1$aCambridge :$cCambridge University Press,$d2019. 215 $a1 online resource (83 pages) $cdigital, PDF file(s) 225 1 $aCambridge elements. Elements in the philosophy of biology, 2515-1126 300 $aTitle from publisher's bibliographic system (viewed on 29 Jan 2020). 311 $a1-108-72750-6 327 $aCover -- Title page -- Copyright page -- Philosophy of Immunology -- Contents -- 1 Introduction: The Centrality of Immunity in Biology and Medicine -- 2 Immunity: A Matter of Defense? -- 2.1 Historically, Immunity Has Been Understood As the Capacity of an Organism to Defend Itself against Pathogens -- 2.2 Defensive Immune Mechanisms Have Been Identified in Virtually All Living Things -- 2.3 Extended Immunity: Immunity Goes Well Beyond Defense -- 2.4 Accounting for the Evolution of Immunological Processes and Attributing a Function to the Immune System Have Become Difficult -- 2.5 Is It Still Possible to Offer a Precise and Simple Definition of Immunity? -- 3 The Unity of the Individual: Self-Nonself, Autoimmunity, Tolerance, and Symbiosis -- 3.1 From Early Reflections about Immunological Individuality to the Concepts of "Self" and "Nonself" -- 3.2 Autoimmunity, Tolerance, and Symbiotic Interactions with Microbes -- 3.3 Immunology's Contribution to the Definition of Biological Individuality -- 3.4 The Role of the Immune System in Turning a Set of Heterogeneous Constituents into an Integrated Individual -- 3.5 Combining Different Approaches to Biological Individuality -- 4 Cancer as a Deunification of the Individual -- 4.1 How the Immune System Restrains Cancer: The Complex History of the Idea of Immunosurveillance -- 4.2 The Dual Action of the Immune System in Both Restraining and Promoting Cancer: Immunoediting and Beyond -- 4.3 Immune-Cancer Interactions: Current Views and Clinical Applications -- 4.4 Role of the Immune System in the Breakdown of Biological Individuality That Characterizes Cancer -- 5 Neuroimmunology: The Intimate Dialogue between the Nervous System and the Immune System -- 5.1 From Psychoneuroimmunology and Neuroimmunology to Present-Day Characterizations of the Dialogue between the Nervous and the Immune Systems. 327 $a5.2 Interactions between the Nervous and the Immune System in Health -- 5.3 Interactions between the Nervous and the Immune System in Pathological Contexts -- 5.4 Mapping the Different Conceptual Questions Raised by Neuroimmunology -- 5.4.1 Interaction: How Do the Nervous and the Immune System Interact? -- 5.4.2 Similarity: Are the Nervous and the Immune System Structurally and/or Functionally Similar? -- 5.4.3 Overlap: To What Extent Do the Nervous and the Immune System Overlap or Even Constitute a Single System? -- 5.4.4 Origins: Do the Nervous and the Immune System Share Evolutionary Origins? -- 5.4.5 Control: Does the Nervous System Control the Immune System or the Other Way Around? -- 5.5 Conclusion: Some Philosophical Consequences -- References -- Acknowledgments. 330 $aImmunology is central to contemporary biology and medicine, but it also provides novel philosophical insights. Its most significant contribution to philosophy concerns the understanding of biological individuality: what a biological individual is, what makes it unique, how its boundaries are established and what ensures its identity through time. Immunology also offers answers to some of the most interesting philosophical questions. What is the definition of life? How are bodily systems delineated? How do the mind and the body interact? In this Element, Thomas Pradeu considers the ways in which immunology can shed light on these and other important philosophical issues. This title is also available as Open Access on Cambridge Core. 410 0$aCambridge elements.$pElements in the philosophy of biology,$x2515-1126. 606 $aImmunology$xPhilosophy 615 0$aImmunology$xPhilosophy. 676 $a616.079 700 $aPradeu$b Thomas$0956726 801 0$bUkCbUP 801 1$bUkCbUP 906 $aBOOK 912 $a9910585962803321 996 $aPhilosophy of immunology$92904712 997 $aUNINA