LEADER 03786nam 2200997z- 450 001 9910585944103321 005 20231214133037.0 035 $a(CKB)5600000000483037 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/91229 035 $a(EXLCZ)995600000000483037 100 $a20202208d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aIn Vitro and In Vivo Models of Colorectal Cancer for Clinical Application 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 electronic resource (222 p.) 311 $a3-0365-3966-2 311 $a3-0365-3965-4 330 $aThe Special Issue "In Vitro and In Vivo Models of Colorectal Cancer for Clinical Application", edited by Marta Baiocchi and Ann Zeuner for Cancers, collects original research papers and reviews, depicting the current state and the perspectives of CRC models for preclinical and translational research. Original research papers published in this issue focus on some of the hottest topics in CRC research, such as circulating tumor cells, epigenetic regulation of stemness states, new therapeutic targets, molecular CRC classification and experimental CRC models such as organoids and PDXs. Additionally, four reviews on CRC stem cells, immunotherapy and drug discovery provide an updated viewpoint on key topics linking benchtop to bedside research in CRC. 606 $aResearch & information: general$2bicssc 606 $aBiology, life sciences$2bicssc 606 $aMicrobiology (non-medical)$2bicssc 610 $acolorectal cancer 610 $aorganoids 610 $a3D bioprinting 610 $apatient-derived xenograft 610 $acancer-on-chip 610 $adrug combination 610 $acancer stem cells 610 $adrug resistance 610 $aclinical trials 610 $atumor-initiating cells 610 $atumor heterogeneity 610 $apatient-derived cancer models 610 $asingle-cell RNA-sequencing 610 $atumor metabolism 610 $atranscriptional programs 610 $atumor cell differentiation 610 $aimmunotherapy 610 $amethods 610 $achromosomal instability 610 $aDNA damage 610 $atargeted therapy 610 $adecitabine 610 $acolon cancer 610 $aDNA methylation 610 $aclinical translation study 610 $amachine learning 610 $apatient-derived tumor organoid 610 $aprecision medicine 610 $aradiation response 610 $arectal cancer 610 $aPDX model 610 $aCRC 610 $amutation analysis 610 $ahistological examination 610 $aanimal models 610 $ain vitro culture 610 $acancer stem cell methods 610 $aSATB2 610 $acolorectal carcinoma 610 $aprognosis 610 $aCDX2 610 $acirculating tumor cells 610 $aCTC cluster 610 $asize-based method 610 $aScreenCellŽ 610 $aepithelial mesenchymal transition 610 $ahypoxia 610 $aHIF-1? 610 $aimmunofluorescence analysis 610 $asequential filtration 615 7$aResearch & information: general 615 7$aBiology, life sciences 615 7$aMicrobiology (non-medical) 700 $aBaiocchi$b Marta$4edt$01318513 702 $aZeuner$b Ann$4edt 702 $aBaiocchi$b Marta$4oth 702 $aZeuner$b Ann$4oth 906 $aBOOK 912 $a9910585944103321 996 $aIn Vitro and In Vivo Models of Colorectal Cancer for Clinical Application$93033349 997 $aUNINA