LEADER 01433nam 2200361 n 450 001 996395556803316 005 20200824121208.0 035 $a(CKB)3810000000011217 035 $a(EEBO)2248519193 035 $a(UnM)ocm99883376e 035 $a(UnM)99883376 035 $a(EXLCZ)993810000000011217 100 $a19940103d1656 uy 101 0 $aeng 135 $aurbn||||a|bb| 200 14$aThe fulness and freeness of Gods grace in Jesus Christ$b[electronic resource] $edeclared in two general points: first, that personal election is no ground of the saints perseverance in the grace of God by Jesus Christ. Secondly, in what sense the scriptures speake the saints perseverance in that grace. The third part$fBy Francis Duke 210 $aLondon $cPrinted by T.N. for Wil. Milward, without Westminster Hall Gate, and Miles Michael within the Gate$d1656 215 $a[1+] p 300 $aA fragment: title page only. 300 $aReproduction of original in the British Library. 330 $aeebo-0018 606 $aGrace (Theology)$vEarly works to 1800 608 $aTitle pages$zEngland$y17th cent. 615 0$aGrace (Theology) 700 $aDuke$b Francis$01013353 801 0$bCu-RivES 801 1$bCu-RivES 801 2$bCStRLIN 801 2$bCu-RivES 906 $aBOOK 912 $a996395556803316 996 $aThe fulness and freeness of Gods grace in Jesus Christ$92389857 997 $aUNISA LEADER 01034nam a2200241 i 4500 001 991000247029707536 008 090520s2009 it 100 0 ita d 020 $a9788862200684 035 $ab13831215-39ule_inst 040 $aDip.to Filologia Class. e Scienze Filosofiche$bita 082 $a179.7 100 1 $aFlores d'Arcais, Paolo $0162882 245 10$aA chi appartiene la tua vita? :$buna riflessione filosofica su etica, testamento biologico, eutanasia e diritti civili nell'epoca oscurantista di Ratzinger e Berlusconi /$cPaolo Flores D'Arcais 260 $aMilano :$bPonte alle Grazie,$c[2009] 300 $a158 p. ;$c21 cm 440 0$aSaggi 650 4$aVita umana$xMorale 907 $a.b13831215$b25-11-09$c20-05-09 912 $a991000247029707536 945 $aLE007 179 FLO 01.01$g1$i2007000191354$lle007$nLE007 2009 Lippolis$op$pE12.50$q-$rl$s- $t0$u5$v0$w5$x0$y.i15036388$z25-11-09 996 $aA chi appartiene la tua vita?$9233648 997 $aUNISALENTO 998 $ale007$b20-05-09$cm$da $e-$fita$git $h2$i0 LEADER 06683nam 2201957z- 450 001 9910585938903321 005 20220812 035 $a(CKB)5600000000483093 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/91173 035 $a(oapen)doab91173 035 $a(EXLCZ)995600000000483093 100 $a20202208d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aNovel Strategies in the Development of New Therapies, Drug Substances and Drug Carriers 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 online resource (450 p.) 311 08$a3-0365-4646-4 311 08$a3-0365-4645-6 330 $aThis book is conceived to promote synergy between research and industrial activities in the design and development of new drugs and, therefore, is not limited to any specific aspect of development. It covers the entire process from the identification of a molecular target, studies of drug-protein interactions, the modeling and optimization of the functional activity, design and chemical synthesis, biological evaluation, and the development of new pharmaceutical carriers.The original articles and reviews are focused on the design and development of new anticancer treatments, new anticancer low-molecular-weight agents as potential drug substances, and the elucidation of their mechanisms of action. The book also includes studies on novel modulators of the serotonergic system used to treat central nervous system disorders, novel agents against infectious diseases, and the development of anti-plasmodial and anti-inflammatory agents. The successful identification of new compounds for development as drug substances comes from rich sources of medicinal plants and medicinal chemistry approaches. 606 $aChemistry$2bicssc 606 $aResearch & information: general$2bicssc 610 $a1,2,4-triazole 610 $a25 vitamin D 24-hydroxylase 610 $aA-ring 610 $aactive substance delivery systems 610 $aactive substance-controlled release 610 $aADME 610 $aalkaloids 610 $aalpha-ketoglutarate 610 $aanalogue actions at genes 610 $aanti-depressant therapy 610 $aanti-inflammatory activity 610 $aanticancer activity 610 $aanticancer drug 610 $aanticancer drugs 610 $aantidepressants 610 $aantimalarial 610 $aantimicrobial activity 610 $aantimicrobial compounds 610 $aantimicrobial peptide (AMP) 610 $aantioxidant activity 610 $aantiparasitic agents 610 $aantiviral proteins 610 $aapoptosis 610 $aAu(III) complex 610 $abiomarker 610 $abiomedical hydrogels 610 $acalcilytic 610 $acalcimimetic 610 $acalcium-sensing receptor 610 $acancer 610 $acancer cells 610 $acancer therapy 610 $acancer treatment 610 $aCD-ring 610 $acell cycle 610 $acell invasion 610 $acell migration 610 $aChelidonium majus 610 $aChIP-chip analysis 610 $acolon cancer 610 $acolorectal cancer 610 $acopper (II) complexes 610 $aCRISPR/Cas9 610 $acyclooxygenase 610 $aCYP24A1 610 $aCYP24A1-dependent metabolism 610 $aCYP27B1 610 $acytotoxic activity 610 $acytotoxic study 610 $acytotoxicity 610 $adefense-related proteins 610 $adepression 610 $adermaseptin 610 $adistal enhancers 610 $adrug 610 $adrug design 610 $adrug design and discovery 610 $adrug discovery 610 $adual 5-HT1A/SERT activity 610 $aelectrochemistry 610 $aenantiomer 610 $afluorine 610 $afrog skin peptides 610 $agenistein 610 $agenome editing 610 $aglucose metabolism 610 $aglycoconjugates 610 $agold 610 $agold electrode 610 $agreater celandine 610 $ahemolysis 610 $ahigh-grade serous ovarian cancer cells 610 $ahistone deacetylase (HDAC) 610 $ahistone H3 acetylation 610 $aHT-29 610 $ahuman DNA topoisomerase 610 $ahydrogels for cosmetology 610 $ahydrogels for dermatology 610 $aIL-8 610 $ainflammation 610 $aJNK 610 $alatex 610 $aLHRH 610 $alung cancer 610 $amajor latex protein 610 $aMALDI 610 $ametabolite 610 $ametallodrugs 610 $amethotrexate 610 $amolecular docking 610 $amolecular modeling 610 $amultimodal activity 610 $an/a 610 $ananoparticles 610 $aorganometallic 610 $aoxidation mechanisms 610 $aPhyllomedusa bicolor 610 $aPlasmodium falciparum (P. falciparum) 610 $aPRI-2191 610 $aproliferation 610 $aprostate cancer 610 $aproteome analysis 610 $apyridazinone 610 $apyrido[1,2-c]pyrimidines 610 $aresveratrol 610 $arickets 610 $aRNA polymerase II 610 $aSAR 610 $aself-assembled monolayer 610 $aside-chain 610 $aspectroscopic data 610 $asplit luciferase-based biosensor 610 $astereospecificity 610 $asynthesis 610 $atargeted therapy 610 $atetrahydro-?-carbolines 610 $aTGF-? 610 $atherapeutic peptides 610 $athiourea 610 $atranscription 610 $atransdermal active substance delivery systems 610 $aVEGF 610 $avitamin D 610 $avitamin D analogs 610 $avitamin D biology and action 610 $avitamin D hormone (1,25(OH)2D3) 610 $avitamin D receptor 610 $avitamin D3 610 $aWarburg effect 615 7$aChemistry 615 7$aResearch & information: general 700 $aKutner$b Andrzej$4edt$01313410 702 $aBrown$b Geoffrey$4edt 702 $aKallay$b Eniko?$4edt 702 $aKutner$b Andrzej$4oth 702 $aBrown$b Geoffrey$4oth 702 $aKallay$b Eniko?$4oth 906 $aBOOK 912 $a9910585938903321 996 $aNovel Strategies in the Development of New Therapies, Drug Substances and Drug Carriers$93031397 997 $aUNINA