LEADER 02483nam 2200409 450 001 9910583500103321 005 20180911110645.0 010 $a0-08-102355-3 010 $a1-78548-265-3 035 $a(CKB)4100000002037915 035 $a(MiAaPQ)EBC5245949 035 $a(PPN)233899650 035 $a(EXLCZ)994100000002037915 100 $a20180220h20182018 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 10$aLong non-coding RNA $ethe dark side of the genome /$fAntonin Morillon 210 1$aLondon, [England] ;$aOxford, England :$cISTE Press :$cElsevier,$d2018. 210 4$d©2018 215 $a1 online resource (173 pages) 320 $aIncludes bibliographical references and index. 327 $aForeword -- Preface -- Non-coding RNA, its history and discovery timeline -- Definition and families of long non-coding RNA -- Biological functions of long non-coding RNA -- Non-coding RNA in development -- Long non-coding RNA and cancer -- Concluding perspectives. 330 $a"The dark side of the genome represents vast domains of the genome that are not encoding for proteins--the basic bricks of cellular structure and metabolism. Up to 98% of the human genome is non-coding and produces so-called long non-coding RNA. Some of these non-coding RNA play fundamental roles in cellular identity, cell development and cancer progression. They are now widely studied in many organisms to understand their function. Here, we review this expanding field of research and present the broad functional diversities of those molecules and their putative fundamental and therapeutic roles. We develop the recent history of non-coding RNA, their very much debated classification and how they raise a formidable interest for developmental and tumorigenesis biology. Using classical examples and an extensive bibliography, we illustrate the most studied and attractive examples of these long non-coding RNA, how they interface with epigenetics, genome integrity and expression and what are the current models of their regulatory mechanisms."--Page 4 of cover. 606 $aNon-coding RNA$vLaboratory manuals 615 0$aNon-coding RNA 676 $a572.88 700 $aMorillon$b Antonin$0988949 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910583500103321 996 $aLong non-coding RNA$92261525 997 $aUNINA LEADER 03702nam 2200649 a 450 001 9910672070203321 005 20221108043105.0 010 $a958-695-722-5 035 $a(CKB)2670000000256490 035 $a(EBL)3201511 035 $a(OCoLC)923035823 035 $a(SSID)ssj0001028924 035 $a(PQKBManifestationID)11958900 035 $a(PQKBTitleCode)TC0001028924 035 $a(PQKBWorkID)11027974 035 $a(PQKB)10923321 035 $a(MiAaPQ)EBC3201511 035 $a(OCoLC)929374654 035 $a(FlNmELB)ELB69396 035 $a(EXLCZ)992670000000256490 100 $a20201209e2011 || | 101 0 $aspa 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aSalarios, vida cotidiana y condiciones de vida en Bogota? durante la primera mitad del siglo XX$b[recurso electronico] /$fMari?a del Pilar Lo?pez Uribe 210 $aBogota? $cUniversidad de los Andes$d2011 215 $a1 online resource (250 p.) 225 0 $aPrometeo. Maestri?a 300 $aDescription based upon print version of record. 311 $a958-695-635-0 327 $aSalarios, vida cotidiana y condiciones (...); Pa?gina Legal ; Contenido; Agradecimientos; Pro?logo; Introduccio?n; Discursos sobre la modernidad y las necesidades de cambio en las costumbres; Cambios y permanencias en la vida cotidiana bogotana; La ciudad; Los servicios pu?blicos; El agua; La luz; El tele?fono; El transporte; La vida cotidiana de los bogotanos; La vivienda y los alquileres; El vestido; La alimentacio?n; El tiempo libre; Cambios en las condiciones de vida en Bogota?; Revisio?n de la literatura; Literatura internacional sobre salarios, precios y condiciones de vida 327 $aLiteratura sobre salarios, precios y condiciones de vida en ColombiaFuentes primarias cuantitativas; El i?ndice de precios; La regulacio?n y vigilancia de los precios de los alimentos; El problema de la "caresti?a de la vida"; Los salarios reales; La clasificacio?n de los trabajadores; Los salarios reales pu?blicos; Los salarios reales privados; Jornales y demanda laboral de hombres y mujeres; Jornales agri?colas; Las relaciones de bienestar; Diferenciales salariales; Algunos determinantes no monetarios de los cambios en el salario nominal y en las condiciones de vida 327 $aLa industrializacio?n y la agriculturaLas migraciones rurales-urbanas; Las poli?ticas de educacio?n; Legislacio?n laboral, condiciones de trabajo y cuestiones obreras; Accidentes de trabajo y enfermedades; Condiciones higie?nicas; Huelga; Conflictos de trabajo; Desempleo; Otras cuestiones laborales; Conclusiones; Fuentes primarias; Archivos; Perio?dicos; Revistas; Bibliografi?a; Anexo 517 3 $aSalarios, vida cotidiana y condiciones de vida en Bogota? 606 $aSalarios$zColombia 606 $aCosto y nivel de vida$zColombia 606 $aWages$zColombia 606 $aCost and standard of living$zColombia 607 $aBogota? 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