LEADER 02514nam 2200433 450 001 9910583498803321 005 20200604162931.0 010 $a0-12-803370-3 010 $a0-12-803369-X 035 $a(CKB)4100000003836586 035 $a(MiAaPQ)EBC5394962 035 $a(PPN)233902910 035 $a(EXLCZ)994100000003836586 100 $a20180601d2018 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aStructural biology in immunology $estructure/function of novel molecules of immunologic importance /$fedited by Chaim Putterman, David Cowburn, Steven Almo 210 1$aLondon :$cElsevier,$d2018. 215 $a1 online resource (188 pages) 327 $a1. Organization of Immunological Synapses and Kinapses -- 2. Principles of Protein Recognition by Small T-Cell Adhesion Proteins and Costimulatory Receptors -- 3. Synthetic Antibody Engineering: Concepts and Applications -- 4. Natural Killer Cell Receptor -- 5. Structure-Function in Antibodies to Double-Stranded DNA -- 6. The Role of the Constant Region in Antibody-Antigen Interactions: Redefining the Modular Model of Immunoglobulin Structure. 330 $aStructural Biology in Immunology, Structure/Function of Novel Molecules of Immunologic Importance delivers important information on the structure and functional relationships in novel molecules of immunologic interest. Due to an increasingly sophisticated understanding of the immune system, the approach to the treatment of many immune-mediated diseases, including multiple sclerosis, systemic lupus erythematosus, rheumatoid arthritis, and inflammatory bowel disease has been dramatically altered. Furthermore, there is an increasing awareness of the critical role of the immune system in cancer biology. The improved central structure function relationships presented in this book will further enhance our ability to understand what defects in normal individuals can lead to disease.$cSource other than the Library of Congress. 606 $aImmunology 606 $aBiomolecules$xStructure 615 0$aImmunology. 615 0$aBiomolecules$xStructure. 676 $a616.079 702 $aPutterman$b Chaim 702 $aCowburn$b David 702 $aAlmo$b Steven 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910583498803321 996 $aStructural biology in immunology$91909525 997 $aUNINA