LEADER 04585nam 2200589 450 001 9910583463203321 005 20190404152934.0 010 $a0-12-802165-9 035 $a(CKB)3710000000581827 035 $a(EBL)4387032 035 $a(SSID)ssj0001674811 035 $a(PQKBManifestationID)16477675 035 $a(PQKBTitleCode)TC0001674811 035 $a(PQKBWorkID)15017119 035 $a(PQKB)10308866 035 $a(MiAaPQ)EBC4387032 035 $a(PPN)193845245 035 $a(EXLCZ)993710000000581827 100 $a20160213h20162016 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aNutraceuticals $eefficacy, safety and toxicity /$fedited by Ramesh C. Gupta 210 1$aAmsterdam, [Netherlands] :$cAcademic Press,$d2016. 210 4$dİ2016 215 $a1 online resource (1042 p.) 300 $aDescription based upon print version of record. 311 $a0-12-802147-0 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aFront Cover; Nutraceuticals; Copyright Page; Dedication; Contents; List of Contributors; Introduction; Introduction; References; I. Applications of Nutraceuticals in Common Diseases and Disorders; 1 Nutraceuticals in CNS Diseases: Potential Mechanisms of Neuroprotection; Introduction; Polyphenols; Counteracting Oxidative Stress as a Mechanism of Neuroprotection; Direct Antioxidant Action of Quercetin; Potential Role of Hormesis in Neuroprotection; Modulation of the Nrf2-ARE Pathway as a Mechanism of Quercetin Neuroprotection 327 $aModulation of Paraoxonase 2 (PON2) as a Potential Novel Mechanism of Quercetin NeuroprotectionParaoxonase 2; Paraoxonase 2 in the Central Nervous System; Gender Differences in Paraoxonase 2 Expression; Modulation of Paraoxonase 2; Modulation of Paraoxonase 2 by Quercetin; The Issue of Metabolites; Concluding Remarks and Future Directions; Acknowledgments; References; 2 Prevention of Neurodegenerative Disorders by Nutraceuticals; Introduction; Nutraceuticals for the Prevention and Amelioration of AD; Nutraceuticals for the Prevention and Amelioration of PD 327 $aNutraceuticals for the Prevention and Amelioration of ASDConcluding Remarks and Future Directions; References; 3 Cognitive Effects of Nutraceuticals; Introduction; Biological Basis of Cognition; Overview of Cognition; Cellular Basis of Information Storage; Synaptic Plasticity as a Physical Basis for Memory; Biological Basis of Dementia; Nutraceuticals with Potential Cognitive Enhancing Functions; Ginkgo biloba; Positive Effects; Potential Mechanisms; Negative or Null Effects; Bacopa monnieri; Positive Effects; Potential Mechanisms; Negative or Null Effects; Ginseng; Positive Effects 327 $aPotential MechanismNegative or Null Effects; Phosphatidylserine; Positive Effects; Potential Mechanisms; Negative or Null Effects; Caffeine; Positive Effects; Potential Mechanisms; Negative or Null Effects; Centella asiatica, Ephedra sinica, and Crocus sativus; Potential Concerns of Cognitive Enhancement; Concluding Remarks and Future Directions; References; 4 Nutraceuticals in Cardiovascular Diseases; Introduction; Cardiac Dysfunction; Features of Cardiac Disease; Hypertension; Coronary Artery Disease (CAD)-Atherosclerosis; Ischemia; Hypertrophy; Oxidative Stress; Vascular Injury 327 $aBiomarkers of Heart DiseaseTherapeutic Response to Heart Disease; Phytotherapeutic Strategies; Nutraceuticals; Cruciferous Vegetables; Bulbous Plants; Tea; CoQ10; Turmeric; Grape Skin; Fish Oil/Olive Oil; Vegetables; Carnitine; Soy; Concluding Remarks and Future Directions; References; 5 Antiatherosclerotic Efficacy of Nutraceuticals; Introduction; Pathogenesis of Atherosclerosis and Possible Points of Therapeutic Intervention; Role of LDL; Atherosclerotic Plaque Formation; Existing and Emerging Antiatherosclerotic Therapies; Nutraceuticals with Antiatherosclerotic Activity 327 $aAntiatherogenic Natural Agents 606 $aDietary supplements industry$zUnited States 606 $aPharmaceutical industry$zUnited States 606 $aVitamin industry$zUnited States 615 0$aDietary supplements industry 615 0$aPharmaceutical industry 615 0$aVitamin industry 676 $a381.456646 702 $aGupta$b Ramesh C$g(Ramesh Chandra),$f1949- 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910583463203321 996 $aNutraceuticals$92141214 997 $aUNINA