LEADER 03680nam 2200517 450 001 9910583398303321 005 20210201183319.0 010 $a0-12-814190-5 035 $a(CKB)4100000005879636 035 $a(MiAaPQ)EBC5495415 035 $a(EXLCZ)994100000005879636 100 $a20180904h20182018 uy| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 181 $csti$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aNoninvasive prenatal testing (NIPT)$b[electronic resource] $eapplied genomics in prenatal screening and diagnosis /$fedited by Lieve Page-Christiaens, Hanns-Georg Klein 210 1$aLondon :$cAcademic Press,$d[2018] 210 4$dİ2018 215 $a1 online resource (xxvii, 377 pages) $cillustrations 311 $a0-12-814189-1 320 $aIncludes bibliographical references and index. 327 $aSection 1: Cell-freeDNA (CfDNA): overview and technology. Fetal DNA in maternal plasma: an amazing two decades -- Understanding the basics of next generation sequencing in the context of cell-free DNA based NIPT -- The technology and bioinformatics of cell-free DNA based NIPT -- Section 2: CfDNA in clinical practice. Prenatal screening for common aneuploidies before and after the introduction of cell-free DNA based NIPT -- Why cell-free DNA based NIPT for fetal chromosome anomalies is not diagnostic -- The role of cell-free DNA based NIPT in twin pregnancy -- Genomewide testing for autosomal trisomies and copy number variations -- Non-invasive fetal blood group typing -- Noninvasive prenatal diagnosis (NIPD) of monogenic disorders -- Maternal constitutional and acquired copy number variations (CNVs) -- Section 3: Clinical integration. Best practices for integrating cell-free DNA based NIPT into clinical practice -- Quality assurance and standardization of cell-free DNA based NIPT laboratory procedures -- Decisional support for expectant parents -- Cell-free DNA based NIPT and society -- Ethics of cell-free DNA based NIPT for sex chromosome aneuploidies and sex determination -- Cost-effectiveness of cell-free DNA based NIPT: summary of evidence and challenges -- Section 4: The future. Exome sequencing in the evaluation of the fetus with structural anomalies -- Cell-based NIPT: a promising path for prenatal diagnosis -- Maternal circulating nucleic acids as a marker of placental health -- Prenatal treatment of genetic diseases in the unborn 330 $a"Since its introduction in 2012, cell-free (cf) DNA based Non-Invasive Prenatal Testing (NIPT) has been employed to test for fetal chromosome abnormalities, and gene mutations that lead to a variety of genetic conditions, by millions of pregnant women, in more than 90 countries worldwide. With Noninvasive Prenatal Testing (NIPT): Applied Genomics in Prenatal Screening and Diagnosis, Dr Lieve Page-Christiaens and Dr Hanns-Georg Klein have compiled the first authoritative volume on cfDNA NIPT methods and their clinical implementation"--Publisher's description. 606 $aPrenatal diagnosis 606 $aDiagnosis, Noninvasive 606 $aGenetic Testing 606 $aPrenatal Diagnosis 606 $aDNA$xblood 615 0$aPrenatal diagnosis. 615 0$aDiagnosis, Noninvasive. 615 12$aGenetic Testing. 615 22$aPrenatal Diagnosis. 615 22$aDNA$xblood. 676 $a52 702 $aPage-Christiaens$b Lieve 702 $aKlein$b Hanns-Georg 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910583398303321 996 $aNoninvasive prenatal testing (NIPT)$91916106 997 $aUNINA LEADER 02801nam 2200661 450 001 9910789511103321 005 20230617032728.0 010 $a1-283-20805-9 010 $a9786613208057 010 $a1-85539-546-0 035 $a(CKB)2670000000106458 035 $a(EBL)742467 035 $a(OCoLC)745866051 035 $a(SSID)ssj0000522789 035 $a(PQKBManifestationID)12233212 035 $a(PQKBTitleCode)TC0000522789 035 $a(PQKBWorkID)10529029 035 $a(PQKB)11064933 035 $a(MiAaPQ)EBC742467 035 $a(Au-PeEL)EBL742467 035 $a(CaPaEBR)ebr11033966 035 $a(CaONFJC)MIL320805 035 $a(EXLCZ)992670000000106458 100 $a20150406h20052005 uy| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aFuture directions $epractical ways to develop emotional intelligence and confidence in young people /$fDiane Carrington and Helen Whitten 210 1$aStafford :$cNetwork Educational Press Limited,$d[2005] 210 4$dİ2005 215 $a1 online resource (193 p.) 300 $aDescription based upon print version of record. 311 $a1-85539-198-8 320 $aIncludes bibliographical references. 327 $aContents; About the authors; Introducing the book; Section 1: Emotional well-being; Section 2: Choices on leaving school; Section 3: Starting work; Section 4: Future direction; References; Resources 330 $aFuture Directions is specially created to support teachers as they guide their pupils through the exciting and often perplexing period of transition from school to adult life. It provides a series of lesson plans designed to help pupils explore sensitive issues within the security of the classroom. Each lesson includes interactive exercises which will encourage pupils to:. · think for themselves. · recognize their own strengths. · build confidence. · learn how to manage stress. · set realistic goals. · develop communication skills. · make 606 $aEmotional intelligence 606 $aAffect (Psychology)$xStudy and teaching 606 $aAffective education 606 $aEmotions in adolescence 606 $aConfidence in children 615 0$aEmotional intelligence. 615 0$aAffect (Psychology)$xStudy and teaching. 615 0$aAffective education. 615 0$aEmotions in adolescence. 615 0$aConfidence in children. 676 $a373.0114 700 $aCarrington$b Diane$01536853 702 $aWhitten$b Helen 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910789511103321 996 $aFuture directions$93785824 997 $aUNINA