LEADER 01856nam  2200433   450 
001 9910583361603321
005 20180505091515.0
010   $a0-12-812279-X
010   $a0-12-812259-5
035   $a(CKB)3710000001442211
035   $a(MiAaPQ)EBC4921003
035   $a(PPN)228026504
035   $a(EXLCZ)993710000001442211
100   $a20170815h20172017  uy             0
101 0 $aeng
135   $aurcnu||||||||
181   $2rdacontent
182   $2rdamedia
183   $2rdacarrier
200 12$aA paradigm shift to prevent and treat Alzheimer's disease $efrom monotargeting pharmaceuticals to pleiotropic plant polyphenols /$fHoward Friel and Sally Frautschy
210  1$aLondon, England :$cAcademic Press,$d2017.
210  4$dİ2017
215   $a1 online resource (275 pages) $cillustrations
320   $aIncludes bibliographical references at the end of each chapters and index.
327   $aPart I. Pleiotropism -- Monotargeting versus multitargeting -- The pleiotropic pharmacology of plant polyphenols -- Part II. Pleiotropism and Alzheimer's disease -- Primary prevention of Alzheimer's disease -- Secondary prevention of Alzheimer's disease -- Treatment mechanisms in mild to moderate Alzheimer's disease --Pleiotropic theory -- Part III. Rational basis versus strict scrutiny -- Dose-adherence and intent-to-treat.
606   $aAlzheimer's disease$xChemotherapy
606   $aAlzheimer's disease$xPrevention
615  0$aAlzheimer's disease$xChemotherapy.
615  0$aAlzheimer's disease$xPrevention.
676   $a616.831061
700   $aFriel$b Howard$0871918
702   $aFrautschy$b Sally
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910583361603321
996   $aA paradigm shift to prevent and treat Alzheimer's disease$91946736
997   $aUNINA