LEADER 03862nam 2200505 450 001 9910583306303321 005 20230406155341.0 010 $a0-12-813317-1 035 $a(CKB)3790000000543769 035 $a(MiAaPQ)EBC5212818 035 $a(EXLCZ)993790000000543769 100 $a20180201h20182018 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 00$aAlbinism in Africa $ehistorical, geographic, medical, genetic, and psychosocial aspects /$fedited by Jennifer Kromberg, Prashiela Manga 210 1$aLondon, England :$cAcademic Press,$d2018. 210 4$dİ2018 215 $a1 online resource (343 pages) $cillustrations (some color), tables, maps 311 $a0-12-813316-3 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $a1. Introduction and Historical Background / Jennifer G.R. Kromberg -- 2. Clinical Features, Types of Albinism, and Natural History / Jennifer G.R. Kromberg -- 3. Epidemiology of Albinism / Jennifer G.R. Kromberg -- 4. Prevalence and Population Genetics of Albinism: Surveys in Zimbabwe, Namibia, and Tanzania / Patricia M. Lund, Mark Roberts -- 5. Molecular Biology of Albinism / Prashiela Manga -- 6. Dermatological Aspects of Albinism / Sian Hartshorne, Prashiela Manga -- 7. Albinism and the Eye / Susan E.I. Williams -- 8. Low-Vision Rehabilitation and Albinism / Rebecca L. Kammer -- 9. Psychosocial and Cultural Aspects of Albinism / Jennifer G.R. Kromberg -- 10. Genetic Counseling and Albinism / Jennifer G.R. Kromberg -- 11. Genetic Testing, Postnatal, and Prenatal Diagnosis for Albinism / Robyn Kerr, Jennifer G.R. Kromberg -- 12. Albinism and Social Marginalization / Sam Clarke, Jon Beale -- 13. Interventions: Preventive Management, Empowerment, Advocacy, and Support Services / G.R. Kromberg -- 14. A Personal Perspective: Living With Albinism / Nomasonto G. Mazibuko, Jennifer G.R. Kromberg -- 15. Summary and Conclusion / Jennifer G.R. Kromberg, Prashiela Manga. 330 $aAlbinism in Africa: Historical, Geographic, Medical, Genetic, and Psychosocial Aspects provides the first in-depth reference for understanding and treating patients of human albinism in Africa. Leading international contributors examine the historical, geographic, psychosocial, genetic and molecular considerations of importance in effectively and sensitively managing this genetic disorder. Foundational chapters covering the historical and psychosocial aspects of albinism are supplemented by discussions of the pathobiology of the disease, as well as a thorough analysis of the genetics of skin pigmentation, eye pigmentation, hair pigmentation, and incidents of skin cancer involved in the manifestations of this disorder. New prenatal diagnostics and genetic testing methods, genetic risk assessment for individuals, families, and communities, and novel genetic markers that may be used for developing new therapeutics for treating albinism are also discussed in detail. The book provides care management approaches that may be applied to instances of albinism in other regions, along with guiding principles for treating rare genetic disorders and stigmatized patient populations across the globe. 606 $aAlbinism$zAfrica 606 $aPigmentation disorders 606 $aAlbinism 606 $aGenetics, Medical 607 $aAfrica 607 $aAfrica$2fast 615 0$aAlbinism 615 0$aPigmentation disorders. 615 2$aAlbinism. 615 2$aGenetics, Medical. 676 $a616.55 702 $aKromberg$b Jennifer 702 $aManga$b Prashiela 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910583306303321 996 $aAlbinism in Africa$92282829 997 $aUNINA