LEADER 03234oam 2200433 450 001 9910583082303321 005 20190911100031.0 010 $a0-12-812568-3 035 $a(OCoLC)982377515 035 $a(MiFhGG)GVRL08KL 035 $a(EXLCZ)993710000001176206 100 $a20160331h20172017 uy 0 101 0 $aeng 135 $aurun|---uuuua 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 10$aIt's in your DNA $efrom discovery to structure, function and role in evolution, cancer, and aging /$fDr. Eugene Rosenberg, Department of Molecular Microbiology and Biotechnology, Tel Aviv University, Tel Aviv, Israel ; with drawings by Avshalom Falk 210 1$aLondon :$cAcademic Press, an imprint of Elsevier,$d[2017] 210 4$d?2017 215 $a1 online resource (xvii, 199 pages) $cillustrations (some color) 225 0 $aGale eBooks 311 $a0-12-812502-0 320 $aIncludes bibliographical references and index. 327 $a1. The beginning -- 2. Chemistry of DNA -- 3. DNA is the genetic material -- 4. DNA in three dimensions : the double-helix -- 5. Duplicating DNA -- 6. From genes to enzymes -- 7. Cracking the genetic code -- 8. DNA sequencing and PCR -- 9. Jumping genes -- 10. Genetic engineering -- 11. The human genome -- 12. Human microbiome : we are not alone -- 13. Contribution of microbes to the health of humans, animals, and plants -- 14. Origin of nucleic acids and the first cells -- 15. Evolution : from Darwin to the hologenome concept -- 16. DNA and cancer -- 17. DNA, aging, and death. 330 $aIt's in Your DNA: From Discovery to Structure, Function and Role in Evolution, Cancer and Aging describes, in a clear, approachable manner, the progression of the experiments that eventually led to our current understanding of DNA. This fascinating work tells the whole story from the discovery of DNA and its structure, how it replicates, codes for proteins, and our current ability to analyze and manipulate it in genetic engineering to begin to understand the central role of DNA in evolution, cancer, and aging. While telling the scientific story of DNA, this captivating treatise is further enhanced by brief sketches of the colorful lives and personalities of the key scientists and pioneers of DNA research. Major discoveries by Meischer, Darwin, and Mendel and their impacts are discussed, including the merging of the disciplines of genetics, evolutionary biology, and nucleic acid biochemistry, giving rise to molecular genetics. After tracing development of the gene concept, critical experiments are described and a new biological paradigm, the hologenome concept of evolution, is introduced and described. The final two chapters of the work focus on DNA as it relates to cancer and gerontology.--$cSource other than the Library of Congress. 606 $aDNA fingerprinting 606 $aDNA$xAnalysis 615 0$aDNA fingerprinting. 615 0$aDNA$xAnalysis. 676 $a614.1 700 $aRosenberg$b Eugene$0848245 702 $aFalk$b Avshalom 801 0$bMiFhGG 801 1$bMiFhGG 906 $aBOOK 912 $a9910583082303321 996 $aIt's in your DNA$92254007 997 $aUNINA