LEADER 01186nam 2200385Ia 450 001 996394168503316 005 20221108070744.0 035 $a(CKB)3810000000004712 035 $a(EEBO)2240937114 035 $a(OCoLC)11243812 035 $a(EXLCZ)993810000000004712 100 $a19841009d1679 uy | 101 0 $aeng 135 $aurbn||||a|bb| 200 10$aEnglands great interest in the choice of this new Parliament$b[electronic resource] $ededicated to all her free-holders and electors 210 $a[London $cs.n.$d1679] 215 $a4 p 300 $aCaption title. 300 $aSigned: Philanglus. 300 $aReproduction of original in the University of Illinois (Urbana-Champaign Campus). Library. 330 $aeebo-0167 606 $aLiberty 607 $aGreat Britain$xPolitics and government$y1660-1688 615 0$aLiberty. 700 $aPenn$b William$f1644-1718.$0444261 801 0$bEAE 801 1$bEAE 801 2$bUMI 801 2$bm/c 801 2$bUMI 801 2$bWaOLN 906 $aBOOK 912 $a996394168503316 996 $aEnglands great interest in the choice of this new Parliament$92425125 997 $aUNISA LEADER 06295nam 2201597z- 450 001 9910580215803321 005 20220706 035 $a(CKB)5690000000011929 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/87543 035 $a(oapen)doab87543 035 $a(oapen)87543 035 $a(EXLCZ)995690000000011929 100 $a20202207d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aNanomedicine Formulations Based on PLGA Nanoparticles for Diagnosis, Monitoring and Treatment of Disease: From Bench to Bedside 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 online resource (296 p.) 311 08$a3-0365-4490-9 311 08$a3-0365-4489-5 330 $aNanomedicine is among the most promising emerging fields that can provide innovative and radical solutions to unmet needs in pharmaceutical formulation development. Encapsulation of active pharmaceutical ingredients within nano-size carriers offers several benefits, namely, protection of the therapeutic agents from degradation, their increased solubility and bioavailability, improved pharmacokinetics, reduced toxicity, enhanced therapeutic efficacy, decreased drug immunogenicity, targeted delivery, and simultaneous imaging and treatment options with a single system.Poly(lactide-co-glycolide) (PLGA) is one of the most commonly used polymers in nanomedicine formulations due to its excellent biocompatibility, tunable degradation characteristics, and high versatility. Furthermore, PLGA is approved by the European Medicines Agency (EMA) and the Food and Drug Administration (FDA) for use in pharmaceutical products. Nanomedicines based on PLGA nanoparticles can offer tremendous opportunities in the diagnosis, monitoring, and treatment of various diseases.This Special Issue aims to focus on the bench-to-bedside development of PLGA nanoparticles including (but not limited to) design, development, physicochemical characterization, scale-up production, efficacy and safety assessment, and biodistribution studies of these nanomedicine formulations. 517 $aNanomedicine Formulations Based on PLGA Nanoparticles for Diagnosis, Monitoring and Treatment of Disease 606 $aHistory of engineering and technology$2bicssc 606 $aMaterials science$2bicssc 606 $aTechnology: general issues$2bicssc 610 $a3D culture 610 $aamine 610 $aangiotensin 610 $aanimal model 610 $aanti-inflammatory 610 $aantigen release 610 $aatorvastatin calcium 610 $abiocompatible 610 $abiodegradable 610 $ablood-brain barrier (BBB) 610 $abrightness 610 $acancer 610 $acardiovascular 610 $acarrageenan induced inflammation 610 $acentral nervous system 610 $achemoimmunotherapy 610 $achitosan 610 $aclinical translation 610 $aconfocal microscopy 610 $acoumarin 6 610 $acurrent Good Manufacturing Practice (cGMP) 610 $aCy5.5 610 $acytotoxicity 610 $adesign of experiments 610 $aDiI 610 $adouble emulsion solvent evaporation 610 $adouble-emulsion method 610 $adownstream processing 610 $adrug delivery 610 $adrug delivery system 610 $adrug release 610 $adrug release kinetics modeling 610 $adry powder inhalation 610 $aemulsion 610 $aencapsulation 610 $aester and acid-end capped 610 $afluorescent labeling 610 $aFood and Drug Administration (FDA) 610 $aH. pylori 610 $aimmune checkpoint blockade 610 $aimmunogenic cell death 610 $ain vitro 610 $ain vivo neuroimaging 610 $aIndomethacin 610 $ainline sonication 610 $aintracellular internalization 610 $aJO-4 610 $aKatushka 610 $alyophilization 610 $amas receptor 610 $amethotrexate 610 $amicro-implant 610 $amicrofluidic 610 $amicrofluidics 610 $aminimally invasive 610 $amorphology 610 $ananomedicine 610 $ananoparticle 610 $ananoparticles 610 $ananotechnology 610 $aneurodegenerative diseases 610 $aneuroprotective drugs 610 $anuclear medicine 610 $aorthotopic tumors 610 $aparticle-size 610 $aPEGylation 610 $apharmacokinetics (PK) and biodistribution 610 $aphotothermal therapy 610 $aphthalocyanine 610 $aPLA/PLGA 610 $aPLGA 610 $aPLGA diblock copolymer 610 $aPLGA nanoparticles 610 $aPluronic triblock copolymer 610 $aPNA5 glycopeptide 610 $apoly (lactic-co-glycolic acid) (PLGA) 610 $apoly(lactic-co-glycolic acid) 610 $apoly(lactic-co-glycolic acid) (PLGA) 610 $apoly(lactic-co-glycolic) acid 610 $apoly(lactide-co-glycolide) 610 $apolymeric nanoparticles 610 $apolyvinyl alcohol (PVA) 610 $aporous PLGA particles 610 $aquantum yield 610 $aradiolabeled nanoparticles 610 $arhodamine 123 610 $ascale-up manufacturing 610 $asize 610 $aSKOVip-kat 610 $asolid-state characterization 610 $asolvents 610 $aspheroids 610 $astability of fluorescent label 610 $astabilizers 610 $asucrose 610 $asustained release 610 $atangential flow filtration 610 $atrehalose 610 $aTurboFP635 615 7$aHistory of engineering and technology 615 7$aMaterials science 615 7$aTechnology: general issues 700 $aTagit$b Oya$4edt$01313404 702 $aTagit$b Oya$4oth 906 $aBOOK 912 $a9910580215803321 996 $aNanomedicine Formulations Based on PLGA Nanoparticles for Diagnosis, Monitoring and Treatment of Disease: From Bench to Bedside$93031389 997 $aUNINA LEADER 05504nam 2201177z- 450 001 9910346836503321 005 20210211 035 $a(CKB)4920000000095275 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/54075 035 $a(oapen)doab54075 035 $a(oapen)54075 035 $a(EXLCZ)994920000000095275 100 $a20202102d2019 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMultiple-Criteria Decision-Making (MCDM) Techniques for Business Processes Information Management 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2019 215 $a1 online resource (320 p.) 311 08$a3-03897-642-3 330 $aInformation management is a common paradigm in modern decision-making. A wide range of decision-making techniques have been proposed in the literature to model complex business and engineering processes. In this Special Issue, 16 selected and peer-reviewed original research articles contribute to business information management in various current real-world problems by proposing crisp or uncertain multiple-criteria decision-making (MCDM) models and techniques, mostly including multi-attribute decision-making (MADM) approaches, in addition to a single paper proposing an interactive multi-objective decision-making (MODM) approach. Particular attention is devoted to information aggregation operators; 65% of papers dealt with this item. The topics of this Special Issue gained attention in Europe and Asia. A total of 48 authors from seven countries contributed to this Issue. The papers are mainly concentrated in three application areas: supplier selection and rational order allocation, the evaluation and selection of goods or facilities, and personnel selection/partner selection. A number of new approaches are proposed that are expected to attract great interest from the research community. 517 $aMultiple-Criteria Decision-Making 606 $aHistory of engineering and technology$2bicssc 610 $aadaptive neuro-fuzzy inference system (ANFIS) 610 $aaggregation operator 610 $aaggregation operators 610 $aANFIS 610 $abi-directional projection model 610 $abinary discernibility matrices 610 $adecision making 610 $adesirability function 610 $adeterministic finite automata 610 $aDombi operations 610 $aEinstein operations 610 $aevidence theory 610 $afuzzy EDAS 610 $afuzzy sets 610 $agreen supplier 610 $agroup decision-making 610 $ahesitant probabilistic fuzzy Einstein aggregation operators 610 $ahesitant probabilistic fuzzy element (HPFE) 610 $ainteraction operational laws 610 $ainteractive approach 610 $ainterval multiplicative preference relations 610 $alinguistic cubic variable 610 $alinguistic cubic variable Dombi weighted arithmetic average (LCVDWAA) operator 610 $alinguistic cubic variable Dombi weighted geometric average (LCVDWGA) operator 610 $alogistics 610 $aMADM 610 $amaximizing deviation model 610 $aMCDM 610 $aMuirhead mean 610 $amulti-attribute decision making 610 $amulti-attribute decision-making (MADM) 610 $amulti-attribute group decision-making 610 $amulti-criteria decision-making 610 $amulti-hesitant fuzzy sets 610 $amultiobjective optimization 610 $amultiple attribute decision making 610 $amultiple attribute decision making (MADM). 610 $amultiple attributes decision-making 610 $amultiple criteria decision making (MCDM) 610 $amultiple criteria decision-making 610 $amultiple criteria group decision-making 610 $amultiple-criteria decision-making (MCDM) 610 $aneutrosophic sets 610 $anonnegative normal neutrosophic number 610 $aorder allocation 610 $aprioritized average operator 610 $aprojection model 610 $aPythagorean fuzzy set 610 $aPythagorean uncertain linguistic variable 610 $aqueuing systems 610 $areliable group decision-making 610 $arough analytical hierarchical process (AHP) 610 $arough ANP 610 $arough boundary interval 610 $arough number 610 $arough sets 610 $arough weighted aggregated sum product assessment (WASPAS) 610 $ascore function 610 $asingle-valued linguistic neutrosophic interval linguistic number 610 $asubcontractor evaluation 610 $asupplier 610 $asupplier selection 610 $atrapezoidal fuzzy number 610 $atrust interval 610 $aunbalanced linguistic set 610 $auncertain group decision-making support systems 610 $awarehouse 610 $aweighted aggregation operator 615 7$aHistory of engineering and technology 700 $aAntuchevi?ien?$b Jurgita$4auth$01294171 702 $aChatterjee$b Prasenjit$4auth 702 $aZavadskas$b Edmundas Kazimieras$4auth 906 $aBOOK 912 $a9910346836503321 996 $aMultiple-Criteria Decision-Making (MCDM) Techniques for Business Processes Information Management$93023033 997 $aUNINA