LEADER 04521nam 2201021z- 450 001 9910580213903321 005 20220706 035 $a(CKB)5690000000011949 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/87533 035 $a(oapen)doab87533 035 $a(EXLCZ)995690000000011949 100 $a20202207d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aNeurotransmitter-Related Molecular Modeling Studies 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 online resource (188 p.) 311 08$a3-0365-4277-9 311 08$a3-0365-4278-7 330 $aThis book focuses of the neurotransmission phenomenon. By definition, neurotransmitters are chemicals that enable communication, i.e., the flow of nerve impulses between nerve cells or between nerve cells and muscles and glands. Recently, one can distinguish excitatory and inhibitory mediators, both of which are endo-exogenous compounds that control the function of the whole organism. From a chemical point of view, neurotransmitters belong to many different structural groups, such as amino acids (such as glycine), peptides (such as substance P, somatostatin), monoamines (such as noradrenaline or dopamine), purine derivatives (such as adenosine), gases (such as nitrogen, NO, carbon monoxide CO), and acetylcholine. From a medical point of view, disturbances in the concentration of neurotransmitters in the body result in the occurrence of mental disorders and diseases (such as depression, schizophrenia, Parkinson's disease) and contribute to the occurrence of dementia (including Alzheimer's disease), among other diseases. However, the problem is much wider. These disorders can lead to a number of cardiovascular diseases and can lead to the development of vascular diseases of the brain as well as in many other organs. Therefore, pharmacological intervention is a therapy that tries to interfere with regulatory processes year after year. Such treatments improve survival, reduce the frequency of readmission, and improve patients' quality of life. 606 $aChemistry$2bicssc 606 $aResearch & information: general$2bicssc 610 $a3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors 610 $a5-HT receptors 610 $aacetylcholine 610 $aadverse drug reaction 610 $aandrogenetic alopecia 610 $aantibiotics 610 $aatheroprotection 610 $aBDNF 610 $acardiac voltage-gated ion channels 610 $achronic heart failure (CHF) 610 $acognitive impairment 610 $adementia 610 $adepression 610 $adopamine 610 $adysautonomia 610 $aECG study 610 $agastrointestinal tract 610 $agenetic polymorphisms 610 $aglutamate 610 $aguanylate cyclase (GC) 610 $ahalogenated pyrazolines 610 $ainflammation 610 $akinetics 610 $alevodopa 610 $amixed dyslipidemia 610 $amolecular dynamics 610 $amolecular modeling 610 $amonoamine oxidase inhibitors 610 $amouse 610 $amTOR 610 $aneurodegenerative diseases 610 $aneuroprotection 610 $aneurotoxicity 610 $aneurotransmission 610 $aneurotransmitters 610 $aorthostatic hypotension 610 $aoxidative stress 610 $apulmonary arterial hypertension (PAH) 610 $arenin-angiotensin system 610 $areserpine-induced fibromyalgia model 610 $areversibility 610 $arisk factors 610 $aropinirole 610 $aserotonin 610 $aserotonin and dopamine in fibromyalgia 610 $aSGLT2i 610 $asodium-glucose cotransporter 2 inhibitors 610 $astatins 610 $astroke 610 $atiagabine 610 $atype 2 diabetes mellitus 610 $avortioxetine 610 $awhite matter hyperintensities 615 7$aChemistry 615 7$aResearch & information: general 700 $aNowaczyk$b Alicja$4edt$01332311 702 $aGrze?k$b Grzegorz$4edt 702 $aNowaczyk$b Alicja$4oth 702 $aGrze?k$b Grzegorz$4oth 906 $aBOOK 912 $a9910580213903321 996 $aNeurotransmitter-Related Molecular Modeling Studies$93040814 997 $aUNINA LEADER 04441nam 2201381z- 450 001 9910404088103321 005 20210211 010 $a3-03928-503-3 035 $a(CKB)4100000011302257 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/46257 035 $a(oapen)doab46257 035 $a(EXLCZ)994100000011302257 100 $a20202102d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aEmerging Memory and Computing Devices in the Era of Intelligent Machines 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 online resource (276 p.) 311 08$a3-03928-502-5 330 $aComputing systems are undergoing a transformation from logic-centric towards memory-centric architectures, where overall performance and energy efficiency at the system level are determined by the density, performance, functionality and efficiency of the memory, rather than the logic sub-system. 606 $aHistory of engineering and technology$2bicssc 610 $a3D-stacked 610 $aanalogue computing 610 $aannealing temperatures 610 $aassociative processor 610 $aBCH 610 $abioelectronic devices 610 $abiologic gate 610 $abiomemory 610 $abionanohybrid material 610 $abioprocessor 610 $abipolar resistive switching characteristics 610 $ablockchain 610 $achalcogenide 610 $acharacter recognition 610 $acharge spreading 610 $aconductive filament 610 $aconfigurable logic-in-memory architecture 610 $aconvolutional neural networks 610 $acrossbar 610 $acrossbar array 610 $aCUDA 610 $adata retention 610 $adecoder 610 $aDRAM 610 $adynamic voltage scaling 610 $aECG 610 $aelectrochemical metallization (ECM) 610 $aelectrochemical metallization cell 610 $aemerging technologies 610 $aFast Fourier Transform 610 $aflash memory 610 $aflip-flop 610 $afloating gate 610 $aGalois field 610 $aGPU 610 $aguide training 610 $aHebbian training 610 $ahybrid 610 $aiBM 610 $aimage classification 610 $ain-DRAM cache 610 $ain-memory computing 610 $aInternet of things 610 $aion conduction 610 $alogic-in-memory 610 $alow-latency 610 $alow-power 610 $alow-power technique 610 $amagnetic tunnel junction 610 $amagnetoresistive random access memory 610 $amatrix-vector multiplication 610 $aMCU (microprogrammed control unit) 610 $amemory wall 610 $amemristor 610 $amulti-level cell 610 $an/a 610 $ananoparticles 610 $aneuromorphic computing 610 $aneuromorphic system 610 $anon-von neumann architecture 610 $anon-von Neumann architecture 610 $anonvolatile memory 610 $anucleic acid 610 $aOxygen-related trap 610 $aperpendicular Nano Magnetic Logic (pNML) 610 $aphase change memory 610 $aplasma treatment 610 $apower gating 610 $aprogrammable ramp-down current pulses 610 $aprotein 610 $aquantum point contact 610 $areal-time system 610 $aresistance switching mechanism 610 $aresistive memory 610 $aresistive random access memory (RRAM) 610 $aRISC-V 610 $aself-directed channel (SDC) 610 $asilicon oxide-based memristors 610 $asolution-based dielectric 610 $aSONOS 610 $aSTT-MRAM 610 $asynaptic weight 610 $atask placement 610 $aU-shape recessed channel 610 $avariability 610 $avoltage-controlled magnetic anisotropy 610 $aWeibull distribution 610 $awire resistance 615 7$aHistory of engineering and technology 700 $aKhalili$b Pedram$4auth$01332355 906 $aBOOK 912 $a9910404088103321 996 $aEmerging Memory and Computing Devices in the Era of Intelligent Machines$93040881 997 $aUNINA