LEADER 04099nam 2201213z- 450 001 9910580213403321 005 20220706 035 $a(CKB)5690000000011954 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/87539 035 $a(oapen)doab87539 035 $a(EXLCZ)995690000000011954 100 $a20202207d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aRedox-Active Molecules as Therapeutic Agents 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 online resource (266 p.) 311 08$a3-0365-4381-3 311 08$a3-0365-4382-1 330 $aOxidative stress and altered redox signaling have been described in a plethora of pathological conditions. Redox-active molecules can thus potentially be used to modulate the etiology/progression of such diseases. Recent advances in molecular biology and pharmacology have strengthened this area of research by providing novel mechanistic insights. This book compiles a collection of 13 articles, covering a range of topics from in vitro studies to clinical research, focused on the potential therapeutic effects of either natural or synthetic compounds, applicable to different redox-related diseases. 606 $aBiology, life sciences$2bicssc 606 $aResearch and information: general$2bicssc 610 $a(poly)phenols 610 $aadipose-derived mesenchymal stem cell 610 $aamniotic membrane-derived mesenchymal stem cell 610 $aantioxidant capacity 610 $aantioxidants 610 $aapoptosis 610 $aapurinic/apyrimidinic endonuclease 1 610 $aassisted reproductive technology 610 $aATF4 610 $aBAPN 610 $abioactivity-based assays 610 $abreast cancer 610 $acancer therapy 610 $acardiorenal syndrome 610 $acarnosic acid 610 $aCD IGS rats 610 $acell cycle 610 $acell invasion 610 $achemoresistance 610 $acisplatin 610 $aconditioned medium 610 $acurcumin 610 $acyanidin 610 $aCysteamine 610 $acytotoxicity 610 $aDNA damage 610 $adoxorubicin 610 $aE3330 610 $aembryo 610 $aEMT 610 $aglutathione peroxidase 610 $aglutathione reductase 610 $aGSH 610 $aH2S donors 610 $ahydrogen sulfide 610 $ahypercholesterolemia 610 $ain vitro culture 610 $ain vitro fertilization 610 $ainhibitors 610 $ainvasion 610 $aKEAP1 610 $alactic acid bacteria 610 $alysyl-oxidase 610 $alysyl-oxidase like 2 610 $ametabolomics 610 $ametastases 610 $amigration 610 $amitochondrial reactive oxygen species 610 $aN-acetyl cysteine 610 $an/a 610 $anon-small cell lung cancer 610 $aNRF2 610 $anuclear factor erythroid 2-related factor 2 (Nrf2) 610 $aoxidative stress 610 $aOxPhos 610 $aperoxiredoxin 3 610 $apro-oxidant therapy 610 $aprostate cancer 610 $areactive oxygen species 610 $aredox signaling 610 $aRubus genus 610 $aselenium-enriched Enterococcus faecium 610 $aselenium-enriched Streptococcus thermophilus 610 $aSGK1 610 $asildenafil 610 $asystemic sclerosis 610 $athiostrepton 610 $athiosulfate 610 $averbascoside 610 $awithanolide 610 $ayeast-based discovery platform 615 7$aBiology, life sciences 615 7$aResearch and information: general 700 $aFernandes$b Ana Sofia$4edt$01328210 702 $aFernandes$b Ana Sofia$4oth 906 $aBOOK 912 $a9910580213403321 996 $aRedox-Active Molecules as Therapeutic Agents$93038430 997 $aUNINA