LEADER 03391nam 2200889z- 450 001 9910580212203321 005 20231214133450.0 035 $a(CKB)5690000000011966 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/87550 035 $a(EXLCZ)995690000000011966 100 $a20202207d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aOxidative Stress and Exercise 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 electronic resource (176 p.) 311 $a3-0365-4201-9 311 $a3-0365-4202-7 330 $aAlthough regular moderate-intensity exercise can activate important cell adaptive properties, sporadic and strenuous bouts of exercise may induce oxidative stress due to an augmented production of reactive metabolites of oxygen (ROS) and nitrogen free radical species (RNS). Exercise-induced free radical formation may impair cell function by oxidatively modifying nucleic acids, where DNA damage and insufficient repair may lead to genomic instability. Likewise, lipid and protein damage are significant cellular events that can elicit potentially toxic perturbations in cellular homeostasis. This book focuses on aspects of exercise-induced oxidative stress while taking into consideration the basic mechanisms, consequences and function of ROS production, and whether antioxidants may either support or hinder these responses. 606 $aResearch & information: general$2bicssc 606 $aBiology, life sciences$2bicssc 610 $aApoE 610 $aexercise 610 $aantioxidants 610 $aoxidative stress 610 $acognition 610 $amotor 610 $avitamin E 610 $avitamin C 610 $aaging 610 $aAlzheimer's disease 610 $alymphocytes 610 $amitochondrial transmembrane potential decline 610 $athiobarbituric acid reactive substance 610 $aprotein carbonyl 610 $askeletal muscle 610 $aobesity 610 $afatigue 610 $adiazoxide 610 $acatalase 610 $asuperoxide dismutase 610 $aoxidized glutathione 610 $areduced glutathione 610 $ahemoglobin 610 $apower output 610 $aeccentric exercise 610 $aredox status 610 $aerythrocyte 610 $ametabolism 610 $aprobiotics 610 $aphysical exercise 610 $amale cyclists 610 $aoxidative stress biomarkers 610 $aantioxidative enzymes 610 $aultraendurance exercise 610 $amuscle injury 610 $adiet 610 $areactive oxygen species 610 $aadipose tissue 610 $aantioxidant supplement 610 $acircadian rhythms 610 $areactive oxygen and nitrogen species (RONS) 610 $aexercise training 610 $aantioxidant 615 7$aResearch & information: general 615 7$aBiology, life sciences 700 $aDavison$b Gareth$4edt$01277777 702 $aMcClean$b Conor$4edt 702 $aDavison$b Gareth$4oth 702 $aMcClean$b Conor$4oth 906 $aBOOK 912 $a9910580212203321 996 $aOxidative Stress and Exercise$93012037 997 $aUNINA