LEADER 05907nam 2201573z- 450 001 9910580210103321 005 20231214133005.0 035 $a(CKB)5690000000011987 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/87449 035 $a(EXLCZ)995690000000011987 100 $a20202207d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aThe Origin and Early Evolution of Life$ePrebiotic Systems Chemistry Perspective 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 electronic resource (320 p.) 311 $a3-0365-4470-4 311 $a3-0365-4469-0 330 $aWhat is life? How, where, and when did life arise? These questions have remained most fascinating over the last hundred years. Systems chemistry is the way to go to better understand this problem and to try and answer the unsolved question regarding the origin of Life. Self-organization, thanks to the role of lipid boundaries, made possible the rise of protocells. The role of these boundaries is to separate and co-locate micro-environments, and make them spatially distinct; to protect and keep them at defined concentrations; and to enable a multitude of often competing and interfering biochemical reactions to occur simultaneously. The aim of this Special Issue is to summarize the latest discoveries in the field of the prebiotic chemistry of biomolecules, self-organization, protocells and the origin of life. In recent years, thousands of excellent reviews and articles have appeared in the literature and some breakthroughs have already been achieved. However, a great deal of work remains to be carried out. Beyond the borders of the traditional domains of scientific activity, the multidisciplinary character of the present Special Issue leaves space for anyone to creatively contribute to any aspect of these and related relevant topics. We hope that the presented works will be stimulating for a new generation of scientists that are taking their first steps in this fascinating field. 517 $aOrigin and Early Evolution of Life 606 $aResearch & information: general$2bicssc 606 $aBiology, life sciences$2bicssc 610 $aorigin of life 610 $apeptidyl-transferase center 610 $apseudo-symmetry 610 $aproto-ribosome 610 $aSymR 610 $aemergence of biological systems 610 $aRNA ligation 610 $adimerization 610 $astandard genetic codes 610 $acodon assignment 610 $atRNA 610 $aaminoacyl-tRNA synthetase classes 610 $athiophene 610 $aacetylene 610 $atransition metal sulfides 610 $ahydrothermal conditions 610 $aearly metabolism 610 $aorigin-of-life 610 $aprebiotic chemistry 610 $aprotein-monosaccharide recognition 610 $aprotein-monosaccharide interactions 610 $aFRET analysis 610 $aglycocodon theory 610 $aglucose oxidase 610 $aMars 610 $aprebiotic chemical evolution 610 $aearly Earth 610 $aastrobiology 610 $aCHNOPS 610 $atransition elements 610 $asample return 610 $aexoplanets 610 $acomplex organic molecules 610 $aastrochemistry 610 $ainterstellar medium 610 $amolecular ices 610 $asolid state 610 $aprotoplanetary disks 610 $astar forming regions 610 $acomets 610 $avesicles 610 $adivision 610 $aurea-urease enzymatic reaction 610 $abending modulus 610 $abudding 610 $aADE theory 610 $adynamic kinetic stability 610 $acognition 610 $achemical evolution 610 $asystems chemistry 610 $ametabolism 610 $anetwork expansion simulation 610 $atemperature 610 $athermodynamics 610 $aprotocell 610 $acompartment 610 $asolid interface 610 $alipid 610 $apolymerization 610 $acyclic nucleotides 610 $aautocatalytic set 610 $aosmotic pressure 610 $acell division 610 $alipid membrane 610 $abistable reaction system 610 $atemplate-directed RNA synthesis 610 $aorigin of genetic code 610 $atime order of canonical amino acids 610 $aproto-metabolism 610 $achirogenesis 610 $aquartz 610 $aamino acids 610 $aradiation damage 610 $aGC×GC-TOFMS 610 $aorigins of life 610 $aprebiotic membranes 610 $aprotoamphiphiles 610 $ametal ions 610 $ahot springs 610 $aN-acyl amino acid 610 $aanalogue conditions 610 $aviroids 610 $aribozyviruses 610 $aprimordial replicators 610 $aribozymes 610 $abilayer structure 610 $amolecular dynamics 610 $aaggregation process 610 $aselection 610 $aevolution 610 $aFenton chemistry 610 $areduced phosphorus 610 $apyrophosphate 610 $achemical complexity 610 $aminerals 610 $aschreibersite 610 $aolivine 610 $aserpentinite 610 $aulexite 615 7$aResearch & information: general 615 7$aBiology, life sciences 700 $aFiore$b Michele$4edt$01312140 702 $aAltamura$b Emiliano$4edt 702 $aFiore$b Michele$4oth 702 $aAltamura$b Emiliano$4oth 906 $aBOOK 912 $a9910580210103321 996 $aThe Origin and Early Evolution of Life$93038915 997 $aUNINA