LEADER 02449nam 2200361z- 450 001 9910569197303321 005 20251017110100.0 035 $a(CKB)5400000000050627 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/81831 035 $a(oapen)doab81831 035 $a(DNLM)1753597 035 $a(EXLCZ)995400000000050627 100 $a20202205d2019 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aParaganglioma: A Multidisciplinary Approach 210 $aAustralia$cExon Publications$d2019 215 $a1 online resource (127 p.) 311 08$a0-9944381-7-6 330 $aParagangliomas and pheochromocytomas are rare tumors of the autonomic nervous system that represent a diagnostic and therapeutic challenge. While the classic sites of origin are the adrenal medulla and the autonomic branches of the lower cranial nerves, they may arise from any site in connection with the autonomic neural branches in the thoracic, abdominal, and head and neck regions. The uncontrolled release of catecholamines by these tumors can be life-threatening. Paragangliomas and pheochromocytomas are the tumor types in which the impact of genetic predisposition factors is the highest. The treatment of paraganglioma and pheochromocytoma requires specialized knowledge and solid experience, which, given the rarity of these diseases, is available only in highly specialized centers. This book includes specific chapters written by experts from several countries that deal with relevant aspects of paraganglioma and pheochromocytoma diagnosis and therapy. Chapter 1 addresses the genetic findings that are most relevant to diagnosis and management, chapter 2 deals with the biochemical diagnosis, chapter 3 with imaging, chapter 4 with the surgical and pharmacological management, mainly of trunk paraganglioma and pheochromocytoma, chapters 5 and 6 with the histopathological, genetic, and clinical characteristics of carotid body, and vagal and tympano-jugular paragangliomas. 517 $aParaganglioma 606 $aMJCL$2bicssc 610 $aParaganglioma 615 7$aMJCL 700 $aMariani-Costantini$b Renato$4edt$01303412 702 $aMariani-Costantini$b Renato$4oth 906 $aBOOK 912 $a9910569197303321 996 $aParaganglioma: A Multidisciplinary Approach$93027014 997 $aUNINA