LEADER 02915nam  2200349z- 450 
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035   $a(CKB)5400000000050637
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/81846
035   $a(oapen)doab81846
035   $a(DNLM)9918434283506676
035   $a(EXLCZ)995400000000050637
100   $a20202205d2022      |y         0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 00$aMetastasis
210   $aAustralia$cExon Publications$d2022
215   $a1 online resource (198 p.)
311 08$a0-645-33202-X 
330   $aMetastasis is the dissemination of neoplastic cells from the primary tumor, and their colonization and growth in another part of the body. The process of metastasis is orchestrated by a complex network of biological events, and our understanding of the processes that regulate metastasis has significantly improved. This open access book provides an in-depth analysis of our understanding of the molecular mechanisms, detection, and clinical management of metastatic cancer. Updates are given on molecular imaging of brain metastasis and recurrence, management of pulmonary nodules for the early diagnosis of lung cancer, surgical management of both primary and metastatic lung cancers, genomic landscapes and tumor evolution of metastatic gynecological cancers, epigenetic changes in metastatic ovarian cancer, microRNAs in metastasis of prostate cancer, hematological toxicity of radiation therapy for bone metastasis, DNA damage response in cancer metastasis, tumor endothelial cells and angiogenesis in cancer metastasis, apoptosis-induced compensatory proliferation in cancer, the potential of targeting apoptosis to overcome chemotherapy resistance, and features  of  metastatic  Ewing  sarcoma. This open access book is aimed primarily at clinicians and scientists, but many areas will also be of interest to the layperson.
606   $aMJCL$2bicssc
610   $aMolecular Imaging of Brain Metastases; Imaging Tests for the Diagnosis of Lung Nodules; Thoracic Surgery for Lung Cancer; Pulmonary Metastases;  Surgery for Pulmonary Metastasis; Metastatic Gynecological Cancers; Epigenetic Changes in Ovarian Cancer Metastasis; Tumor Microenvironment in Ovarian Cancer Metastasis; MetastamiRs; MicroRNAs in Metastatic Prostate Cancer; Hematological Toxicity; Bone Metastasis Radiation Therapy; DNA Damage Response; Cancer Metastasis; Tumor Endothelial Cells in Cancer Metastasis; Apoptosis-Induced Compensatory Proliferation; Targeting Apoptosis to Overcome Chemotherapy Resistance; Metastatic Ewing Sarcoma
615  7$aMJCL
700   $aSergi$b Consolato M$4edt$01303410
702   $aSergi$b Consolato M$4oth
906   $aBOOK
912   $a9910569196303321
996   $aMetastasis$93027012
997   $aUNINA