LEADER 03467nam  2200829z- 450 
001 9910566485503321
005 20220506
035   $a(CKB)5680000000037524
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/80968
035   $a(oapen)doab80968
035   $a(EXLCZ)995680000000037524
100   $a20202205d2022      |y         0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 00$aGastrointestinal Cancers and Personalized Medicine
210   $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022
215   $a1 online resource (136 p.)
311 08$a3-0365-3808-9 
311 08$a3-0365-3807-0 
330   $aGastrointestinal cancers, such as esophageal and gastric cancers, pancreatic cancers, hepatobiliary cancers, colorectal cancers and gastrointestinal stromal tumors, are frequently diagnosed at an advanced stage and have a dismal prognosis. Even in patients with potentially curative cancer, nearly 50\% will develop recurrent disease despite aggressive treatments. A number of biomarkers currently guide treatment decisions for patients with gastrointestinal neoplasms. Major technological advances in genomics have made it possible to identify critical genetic alterations in cancer, furthering oncology along the path to "personalized cancer medicine". Future research efforts will focus on the identification of new biomarkers, moving existing biomarkers into earlier lines of therapy and evaluating new combinations of existing biomarkers and therapies.The aim of this Special Issue is to provide an overview of exciting new research in the area of gastrointestinal tumors that may establish innovative personalized management and precision medicine modalities for individualized care.
606   $aMedicine and Nursing$2bicssc
606   $aPharmacology$2bicssc
610   $abiomarker
610   $achemotherapy-induced peripheral neuropathy
610   $acolon cancer
610   $acolorectal cancer
610   $adiagnosis
610   $adifferential scanning calorimetry
610   $aFFPE
610   $aFOLFIRINOX
610   $aFOLFOX
610   $agastrointestinal cancer
610   $agene signature
610   $ageneralized linear models
610   $agenomics
610   $aimmune checkpoint
610   $aimmunotherapy
610   $aLAG-3
610   $alymphocyte-to-monocyte ratio
610   $amesorectum
610   $amicrosatellite instability
610   $amolecular oncology
610   $amolecular profiling
610   $amRNA expression
610   $an/a
610   $aneuropathy
610   $aneurotoxicity
610   $aneutrophil-to-lymphocyte ratio
610   $aoxaliplatin
610   $apancreatic cysts
610   $aprecision medicine
610   $aprognosis
610   $arectal cancer
610   $asphincter preserving
610   $asurvival
610   $atargeted therapy
610   $athermal liquid biopsy
610   $aVANGL1
610   $aXELOX
615  7$aMedicine and Nursing
615  7$aPharmacology
700   $aMini$b Enrico$4edt$01314121
702   $aNobili$b Stefania$4edt
702   $aMini$b Enrico$4oth
702   $aNobili$b Stefania$4oth
906   $aBOOK
912   $a9910566485503321
996   $aGastrointestinal Cancers and Personalized Medicine$93031732
997   $aUNINA