LEADER 03410nam 2200805z- 450 001 9910566485503321 005 20231214132950.0 035 $a(CKB)5680000000037524 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/80968 035 $a(EXLCZ)995680000000037524 100 $a20202205d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aGastrointestinal Cancers and Personalized Medicine 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 electronic resource (136 p.) 311 $a3-0365-3808-9 311 $a3-0365-3807-0 330 $aGastrointestinal cancers, such as esophageal and gastric cancers, pancreatic cancers, hepatobiliary cancers, colorectal cancers and gastrointestinal stromal tumors, are frequently diagnosed at an advanced stage and have a dismal prognosis. Even in patients with potentially curative cancer, nearly 50\% will develop recurrent disease despite aggressive treatments. A number of biomarkers currently guide treatment decisions for patients with gastrointestinal neoplasms. Major technological advances in genomics have made it possible to identify critical genetic alterations in cancer, furthering oncology along the path to ?personalized cancer medicine?. Future research efforts will focus on the identification of new biomarkers, moving existing biomarkers into earlier lines of therapy and evaluating new combinations of existing biomarkers and therapies.The aim of this Special Issue is to provide an overview of exciting new research in the area of gastrointestinal tumors that may establish innovative personalized management and precision medicine modalities for individualized care. 606 $aMedicine$2bicssc 606 $aPharmacology$2bicssc 610 $aneutrophil-to-lymphocyte ratio 610 $alymphocyte-to-monocyte ratio 610 $aprognosis 610 $arectal cancer 610 $amesorectum 610 $asphincter preserving 610 $amolecular oncology 610 $aprecision medicine 610 $acolorectal cancer 610 $atargeted therapy 610 $amolecular profiling 610 $apancreatic cysts 610 $athermal liquid biopsy 610 $adifferential scanning calorimetry 610 $adiagnosis 610 $ageneralized linear models 610 $agene signature 610 $amRNA expression 610 $aVANGL1 610 $aFFPE 610 $aneurotoxicity 610 $aoxaliplatin 610 $achemotherapy-induced peripheral neuropathy 610 $abiomarker 610 $agenomics 610 $aneuropathy 610 $aFOLFOX 610 $aFOLFIRINOX 610 $aXELOX 610 $agastrointestinal cancer 610 $aLAG-3 610 $aimmune checkpoint 610 $acolon cancer 610 $asurvival 610 $amicrosatellite instability 610 $aimmunotherapy 615 7$aMedicine 615 7$aPharmacology 700 $aMini$b Enrico$4edt$01314121 702 $aNobili$b Stefania$4edt 702 $aMini$b Enrico$4oth 702 $aNobili$b Stefania$4oth 906 $aBOOK 912 $a9910566485503321 996 $aGastrointestinal Cancers and Personalized Medicine$93031732 997 $aUNINA