LEADER 05655nam 2201369z- 450 001 9910566483203321 005 20231214133427.0 035 $a(CKB)5680000000037548 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/81036 035 $a(EXLCZ)995680000000037548 100 $a20202205d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aIdentification and Characterization of Genetic Components in Autism Spectrum Disorders 2019 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 electronic resource (256 p.) 311 $a3-0365-3609-4 311 $a3-0365-3610-8 330 $aThe Identification of the Genetic Components of Autism Spectrum Disorders 2019 will serve as a resource for laboratory and clinical scientists as well as translational-based researchers, primary healthcare providers or physicians, psychologists/psychiatrists, neurologists, developmental pediatricians, clinical geneticists, and other healthcare providers, teachers, caregivers and students involved in autism spectrum disorders (ASD) with the goal to translate information directly to the clinic, education and home setting. Other professionals, students and families might find this textbook of value based on better awareness, causes and understanding of genetic components leading to autism and open avenues for treatment. Genetics play a role with up to 90% of autism, with over 800 currently recognized genes contributing to causes, clinical presentation, treatment, and counseling of family members. This textbook includes 13 chapters divided into three sections (clinical, genetics, other) written by experts in the field dedicated to research and clinical care, description, treatment and generating relevant reviews for ASD and related disorders impacting gene expression, profiling, and pathways. Identification of potential risk factors will be discussed, including obesity, microbiota, malignancy, and the immune system, as well as their direct or indirect contribution to ASD treatment and causation. 606 $aResearch & information: general$2bicssc 606 $aBiology, life sciences$2bicssc 606 $aGenetics (non-medical)$2bicssc 610 $aautism spectrum disorders (ASD) 610 $acancer 610 $aoverlapping genes and gene profiling 610 $asuper-pathways 610 $aphenotypes and diseases 610 $amolecular functions and processes 610 $a15q11.2 BP1-BP2 microdeletion (Burnside-Butler) syndrome 610 $aimprinting 610 $aparent-of-origin effects 610 $aphenotype-genotype correlation 610 $aautism 610 $adevelopmental delays 610 $amotor delays 610 $amicrobiome 610 $agut 610 $aProSAP2 610 $aPhelan McDermid Syndrome 610 $agut?brain interaction 610 $aleaky gut 610 $aIL-6 610 $aSHANK 610 $acollapsin response mediator protein 4 610 $aautism spectrum disorder 610 $aneurodevelopmental disorder 610 $awhole-exome sequencing 610 $aanimal model 610 $asex different phenotypes 610 $a15q11.2 BP1?BP2 microdeletion (Burnside?Butler syndrome) 610 $aNIPA1 610 $aNIPA2 610 $aCYFIP1 610 $aTUBGCP5 genes 610 $aPrader?Willi and Angelman syndromes 610 $amagnesium transporters and supplementation 610 $apotential treatment options 610 $aintellectual disability 610 $aAMPA receptors 610 $aNMDA receptors 610 $aguanine nucleotide exchange factor 610 $asynaptic plasticity 610 $aAutism spectrum disorder 610 $aASD 610 $aObesity 610 $aOverweight 610 $aBody mass index 610 $aBMI 610 $aautism candidate genes 610 $asynaptotagmin-like protein 4 (SYTL4) 610 $atransmembrane protein 187 (TMEM187) 610 $aSYTL4-protein structure 610 $aSTRING-protein-protein interaction 610 $aexpression profile 610 $amicroRNA- interactions 610 $aautism spectrum disorders 610 $abiological networks 610 $agenomics 610 $amulti-omics 610 $anetwork diffusion 610 $adata integration 610 $agenetics 610 $aquantitative traits 610 $astratification by trait severity 610 $aheterogeneity reduction 610 $acase-control association analysis 610 $afragile X syndrome 610 $aRNA toxicity 610 $aDNA methylation 610 $amosaicism 610 $apediatrics 610 $aMS-QMA 610 $aAmplideX 610 $acytokine 610 $amonocyte 610 $a?-glucan 610 $aT cell cytokine 610 $atrained immunity 610 $amaternal immune activation 610 $aepigenetics 610 $amice 610 $apostnatal VPA injection 610 $aSAM 610 $agene expression 610 $ananostring 615 7$aResearch & information: general 615 7$aBiology, life sciences 615 7$aGenetics (non-medical) 700 $aButler$b Merlin G$4edt$01261076 702 $aButler$b Merlin G$4oth 906 $aBOOK 912 $a9910566483203321 996 $aIdentification and Characterization of Genetic Components in Autism Spectrum Disorders 2019$93037291 997 $aUNINA