LEADER 05511nam 2201489z- 450 001 9910566478003321 005 20231214133452.0 035 $a(CKB)5680000000037600 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/80967 035 $a(EXLCZ)995680000000037600 100 $a20202205d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aInnovations in the Integrated Management of Breast Cancer 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 electronic resource (278 p.) 311 $a3-0365-3802-X 311 $a3-0365-3801-1 330 $aBreast cancer is acknowledged as an international priority in healthcare. It is currently the most common cancer in women worldwide, with demographic trends indicating a continuous increase in incidence. Over the years, increasing efforts and resources have been devoted to the search for a systematic and optimized strategy in breast cancer diagnosis and treatment. Today, the Breast Unit model is considered the gold standard in order to ensure optimal patient-centered and research-based clinical services through multidisciplinary and integrated management.Surgical treatment has gradually evolved toward less aggressive approaches with the adoption of new therapeutic strategies. The evolution of evidence-based guidelines in such leading disciplines as radiation and medical oncology has led to a steady improvement in survival rates. This Special Issue will highlight innovations in the integrated management of breast cancer, their potential advantages, and the many open issues that still need to be properly defined and addressed. 606 $aMedicine$2bicssc 606 $aPharmacology$2bicssc 610 $ametastatic breast cancer 610 $abreast surgery 610 $aimmune system 610 $ametabolic derangements 610 $aprecision medicine 610 $aintegrated therapies 610 $aadvanced breast cancer 610 $amTOR inhibitor 610 $aCDK4/6 inhibitor 610 $aendocrine resistance 610 $abreast cancer 610 $apregnancy 610 $achemotherapy 610 $atailoring 610 $apersonalization 610 $aDataMart 610 $areal world data 610 $apredictive model 610 $ahealthcare 610 $abreast-conserving surgery 610 $anon-palpable breast lesions 610 $aimage-guided localization 610 $apreoperative breast localization 610 $abreast ultrasound 610 $alarge database 610 $astandardized data collection 610 $anetworks 610 $anipple-sparing mastectomy 610 $aimmediate breast reconstruction 610 $aacellular dermal matrix (ADM) 610 $aaesthetic and oncological outcomes 610 $aquality of life 610 $arare breast cancer 610 $aosteoclast-like giant cells 610 $agene profiling 610 $aOncotype Dx 610 $aadjuvant treatment 610 $aneoadjuvant chemotherapy 610 $asentinel lymph node 610 $asystemic treatment 610 $alocally advanced breast cancer 610 $amini-invasive treatment 610 $aliver metastases 610 $ahepatic surgery 610 $apersonalized medicine 610 $asarcopenia 610 $aphysical performance 610 $afrailty 610 $aolder cancer patients 610 $aclinical trial 610 $apatient enrollment 610 $aartificial intelligence 610 $amachine learning 610 $alung cancer 610 $aoncology 610 $aweb app 610 $aconventional CT and CT angiography 610 $aDIEP flap planning 610 $amultidisciplinary treatment 610 $aevidence-based medicine 610 $apersonalized treatment 610 $aoncological outcomes 610 $apatient quality of life 610 $anormal breast 610 $abreast pathology 610 $ahormone receptor 610 $ahormone expression 610 $alymphedema 610 $alymphaticovenous anastomosis 610 $avascularized lymph node transfer 610 $alymphatic microsurgery 610 $aradiotherapy 610 $aoligometastatic breast cancer 610 $alocoregional therapy 610 $aCDK4/6 inhibitors 610 $amultidisciplinary 610 $aAMH 610 $aovarian reserve 610 $apregnancy desire 610 $asubtypes breast cancer 610 $amiRNAs 610 $abreast cancer treatment 610 $anext-generation-sequencing 610 $atarget therapy 610 $aold age 610 $asurvival 610 $avitamin D 610 $aductal breast cancer 610 $ain situ breast cancer 610 $alobular breast cancer 610 $ahistology 615 7$aMedicine 615 7$aPharmacology 700 $aFranceschini$b Gianluca$4edt$01326260 702 $aSanchez$b Alejandro Martin$4edt 702 $aMasetti$b Riccardo$4edt 702 $aFranceschini$b Gianluca$4oth 702 $aSanchez$b Alejandro Martin$4oth 702 $aMasetti$b Riccardo$4oth 906 $aBOOK 912 $a9910566478003321 996 $aInnovations in the Integrated Management of Breast Cancer$93037228 997 $aUNINA