LEADER 03187nam 2200817z- 450 001 9910566476303321 005 20220506 035 $a(CKB)5680000000037616 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/80961 035 $a(oapen)doab80961 035 $a(EXLCZ)995680000000037616 100 $a20202205d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aNatural Product from the Deep Sea 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 online resource (116 p.) 311 08$a3-0365-3683-3 311 08$a3-0365-3684-1 330 $aAfter the long history of screening, it is becoming difficult to find novel compounds from microorganisms and plants anywhere in the world. Until now, more than about 30,000 marine natural products have been reported. However, with the development of marine natural products research, the hit rate of new compounds is also decreasing. Scientists are now turning their attention to the deep sea, where a high hit rate of novel compounds is expected. Many small compounds and peptides from microorganisms and sponges are with therapeutic activity are shown in this book. This Special Issue Book, "Natural Products from the Deep Sea", should be useful for the screening of novel and useful compounds from nature. 606 $aMedicine and Nursing$2bicssc 610 $a1H-15N 2D-NMR 610 $aabiotic formation 610 $aAl-crus 3 and Al-crus 7 610 $aanti-Gram-negative bacteria 610 $aanti-inflammatory agent 610 $aantibacterial peptides 610 $aanticancer agent 610 $aantifungal activity 610 $aantioxidant activity 610 $aaplysinopsins 610 $abioactive metabolite 610 $abiosynthetic gene clusters 610 $acellular signal transduction 610 $acrustins 610 $adeep sea marine-derived fungus 610 $adeep-sea organisms 610 $adeep-sea-derived fungus 610 $aDeep-Sea-Derived Streptomyces 610 $adesferrioxamine 610 $adocking study 610 $agenomics 610 $aGNPS molecular network 610 $aharziane diterpenes 610 $ahydrothermal vent 610 $aindoleamine 2,3-dioxygenase 610 $amacrolactam 610 $aMariana Trench 610 $aMicromonospora provocatoris MT25 610 $aMyrothecium sp. 610 $amyrothecol 610 $an-acetylglutaminyl glutamine amide 610 $anatural product 610 $anitric oxide (NO) 610 $aNO inhibition 610 $astress genes 610 $athioester-containing benzoate 610 $aThorectandra choanoides 610 $aTrichoderma 610 $atryptophan alkaloid 610 $a?-glucosidase inhibitory activity 615 7$aMedicine and Nursing 700 $aUmezawa$b Kazuo$4edt$01309572 702 $aUmezawa$b Kazuo$4oth 906 $aBOOK 912 $a9910566476303321 996 $aNatural Product from the Deep Sea$93029403 997 $aUNINA