LEADER 04563nam 2201045z- 450 001 9910566473203321 005 20231214132935.0 035 $a(CKB)5680000000037648 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/81044 035 $a(EXLCZ)995680000000037648 100 $a20202205d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAntimicrobial Resistance and Virulence - 2nd Volume 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 electronic resource (156 p.) 311 $a3-0365-3908-5 311 $a3-0365-3907-7 330 $aThe worldwide dissemination of antimicrobial-resistant bacteria, particularly those resistant to last-resource antibiotics, is a common problem to which no immediate solution is foreseen. In 2017, the World Health Organization (WHO) published a list of antimicrobial-resistant "priority pathogens", which include a group of microorganisms with high-level resistance to multiple drugs, named ESKAPE pathogens, comprising vancomycin-resistant Enterococcus faecium (VRE), methicillin- and vancomycin-resistant Staphylococcus aureus (MRSA and VRSA), extended spectrum ?-lactamase (ESBL) or carbapenem-resistant Klebsiella pneumoniae, carbapenem-resistant Acinetobacter baumannii, carbapenem-resistant Pseudomonas aeruginosa and extended spectrum ?-lactamase (ESBL) or carbapenem-resistant Enterobacter spp. These bacteria also have the ability to produce several virulence factors, which have a major influence on the outcomes of infectious diseases. Bacterial resistance and virulence are interrelated, since antibiotics pressure may influence bacterial virulence gene expression and, consequently, infection pathogenesis. Additionally, some virulence factors contribute to an increased resistance ability, as observed in biofilm-producing strains. The surveillance of important resistant and virulent clones and associated mobile genetic elements is essential to decision making in terms of mitigation measures to be applied for the prevention of such infections in both human and veterinary medicine, being also relevant to address the role of natural environments as important components of the dissemination cycle of these strains. 606 $aResearch & information: general$2bicssc 606 $aBiology, life sciences$2bicssc 606 $aMicrobiology (non-medical)$2bicssc 610 $abiocide 610 $aantibiotic resistance 610 $across-resistance 610 $aaminoglycoside 610 $aadaptation 610 $abiofilm 610 $apyruvate cycle 610 $amastitis 610 $astaphylococci 610 $avirulence factors 610 $agenes 610 $aantimicrobial resistance 610 $ainfant 610 $anewborn 610 $abacteremia 610 $aGram-negative bacteria 610 $adrug resistance 610 $amicrobial 610 $amortality 610 $amicrocosm 610 $aAeromonas 610 $aclimate change 610 $atemperature 610 $apH 610 $awater 610 $aAcinetobacter baumannii 610 $avirulence 610 $awhole-genome sequencing 610 $ainternational high-risk clones 610 $agenomic epidemiology 610 $adogs 610 $aEscherichia coli 610 $aESBL 610 $aCTX-M-15 610 $aCTX-M-1 610 $aCTX-M-32 610 $aCTX-M-55 610 $aCTX-M-14 610 $aqAmpC 610 $aCMY-2 610 $acamel 610 $adomestic 610 $amilk 610 $avirulence genes 610 $aextended-spectrum ?-lactamases 610 $abiofilm formation 610 $aPseudomonas aeruginosa 610 $acarbapenem resistance 610 $aKPC-2 610 $aplasmid 610 $adiabetic foot infections 610 $aStaphylococcus aureus 610 $asubinhibitory concentrations 610 $avirulence-related genes 615 7$aResearch & information: general 615 7$aBiology, life sciences 615 7$aMicrobiology (non-medical) 700 $aOliveira$b Manuela$4edt$01314106 702 $aSilva$b Elisabete$4edt 702 $aOliveira$b Manuela$4oth 702 $aSilva$b Elisabete$4oth 906 $aBOOK 912 $a9910566473203321 996 $aAntimicrobial Resistance and Virulence - 2nd Volume$93031713 997 $aUNINA