LEADER 03859nam 2201189z- 450 001 9910566469503321 005 20231214133357.0 035 $a(CKB)5680000000037685 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/81213 035 $a(EXLCZ)995680000000037685 100 $a20202205d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aTargeting Wnt Signaling in Cancer: Opportunities Abound If We Can Avoid the Sword of Damocles 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 electronic resource (298 p.) 311 $a3-0365-3517-9 311 $a3-0365-3518-7 330 $aDysregulation of Wnt signaling is known to be associated with various cancers. As such, identification of novel Wnt pathway targets in cancer and better characterization of already-known targets present exciting, emerging opportunities for cancer treatment. In this Special Issue, we feature papers which discuss the role of Wnt signaling and associated targets in cancer metabolism, tumor immune response, and tumor microenvironment. Papers discussing a range of Wnt-mediated cancers, including those of the colon, liver, pancreas, synovium, bladder, etc., are included. 517 $aTargeting Wnt Signaling in Cancer 606 $aMedicine$2bicssc 606 $aPharmacology$2bicssc 610 $aWnt signaling 610 $asynovial sarcoma 610 $aTNIK 610 $aNCB-0846 610 $aMYC 610 $ahepatitis B virus 610 $aHBV 610 $acancer 610 $aliver cancer 610 $a?-catenin 610 $aTCF/LEF 610 $apancreatic cancer 610 $apancreatic stellate cells 610 $aCBP 610 $ap300 610 $apancreatitis 610 $afibrosis 610 $ajust-right signaling 610 $aAPC 610 $acolorectal cancer 610 $aRNA-binding proteins 610 $aMusashi 610 $adrug discovery 610 $aNotch signaling 610 $acancer therapy 610 $afungi secondary metabolite derivative 610 $amicroenvironment 610 $aWnt 610 $aAML 610 $adrug target 610 $asignaling 610 $acolorectal 610 $aporcupine 610 $aR-spondin 610 $aserrated 610 $aimmunotherapy 610 $awnt 610 $avitamin D 610 $acolon cancer 610 $aL1 610 $aWnt target genes 610 $acell adhesion 610 $aNF-?B 610 $ainvasion and metastasis 610 $acancer stem cells 610 $aEMT 610 $aLgr5 610 $aWnt/beta-catenin signaling 610 $aangiogenesis 610 $aanti-angiogenic therapy 610 $agastrointestinal cancers 610 $atherapeutic targeting of Wnt signaling 610 $a?-catenin paradox 610 $amolecular targeting 610 $aurothelial cancer 610 $aimmune checkpoint inhibitor 610 $aimmunotherapy resistance 610 $aIBD 610 $acolitis 610 $a?-catenin mutations 610 $atumor metabolism 610 $atumor immunology 610 $amolecular therapeutics 610 $aprecision medicine 610 $aastrocytic brain tumors 610 $aDKKs 610 $aGSK3? 615 7$aMedicine 615 7$aPharmacology 700 $aKahn$b Michael$4edt$01310152 702 $aLai$b Keane$4edt 702 $aKahn$b Michael$4oth 702 $aLai$b Keane$4oth 906 $aBOOK 912 $a9910566469503321 996 $aTargeting Wnt Signaling in Cancer: Opportunities Abound If We Can Avoid the Sword of Damocles$93040916 997 $aUNINA