LEADER 03901nam 2200937z- 450 001 9910566465703321 005 20231214133250.0 035 $a(CKB)5680000000037723 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/81019 035 $a(EXLCZ)995680000000037723 100 $a20202205d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aRedox Imbalance and Mitochondrial Abnormalities in Kidney Disease 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 electronic resource (200 p.) 311 $a3-0365-3757-0 311 $a3-0365-3758-9 330 $aThe kidney performs important functions in the human body and can inflict either acute kidney injury (AKI) or chronic kidney disease (CKD). AKI can be induced by kidney ischemia, drugs such as cisplatin, and heavy metals such as cadmium and arsenic. CKD can be induced by drugs, heavy metals, hypertension, and diabetes, as well as cancer. Importantly, nearly all kidney disorders have been shown to involve redox imbalance, reductive stress, oxidative stress, and mitochondrial abnormalities such as impaired mitochondrial homeostasis, including disrupted mitophagy and deranged mitochondrial unfolded protein responses. Understanding how these redox-related dysregulated pathways operate may give us new insights into how to design novel approaches to fighting kidney disease. This Special Issue of Biomolecules entitled ?Redox imbalance and mitochondrial abnormalities in kidney disease? covers a variety of topics focusing on oxidative stress, mitochondrial dysfunction, and antioxidation enhancement implicated in kidney disease or kidney transplantation. 606 $aMedicine$2bicssc 606 $aPharmacology$2bicssc 610 $adiabetic kidney disease 610 $acaloric restriction 610 $aNADH/NAD+ 610 $aredox imbalance 610 $amitochondrial homeostasis 610 $amitophagy 610 $aoxidative stress 610 $akidney allograft 610 $akidney rejection 610 $aischemia 610 $aacute kidney injury (AKI) 610 $achronic kidney disease (CKD) 610 $atricarboxylic acid (TCA) cycle 610 $amitochondrial metabolism 610 $amitochondrial redox signaling 610 $amitochondrial proteins 610 $aoxidative phosphorylation (OXPHOS) 610 $afatty acid (FA) ?-oxidation 610 $amitochondrial dynamics 610 $abiogenesis 610 $adiabetes 610 $akidney 610 $amitochondria 610 $aOryza sativa 610 $arice husk 610 $aTCA cycle metabolites 610 $akidney diseases 610 $arenalase 610 $achronic kidney disease 610 $amajor adverse cardiovascular outcomes 610 $acadmium 610 $akidney injury 610 $arenal toxicity 610 $aoxidative damage 610 $aproximal tubule 610 $acontrolled oxygenated rewarming 610 $amitochondrial uncoupling 610 $arewarming injury 610 $atemperature paradox 610 $aredox 610 $amitochondrial dysfunction 610 $aSGLT2 610 $amitochondrial reactive oxygen species 610 $aWarburg effect 610 $apodocytopathies 610 $amitochondrial oxidative stress 610 $areactive oxygen species (ROS) 610 $aantioxidant defense 610 $acell death 615 7$aMedicine 615 7$aPharmacology 700 $aYan$b Liang-Jun$4edt$01314102 702 $aYan$b Liang-Jun$4oth 906 $aBOOK 912 $a9910566465703321 996 $aRedox Imbalance and Mitochondrial Abnormalities in Kidney Disease$93031708 997 $aUNINA