LEADER 06078nam 2201825z- 450 001 9910566465303321 005 20231214133342.0 035 $a(CKB)5680000000037727 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/80949 035 $a(EXLCZ)995680000000037727 100 $a20202205d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMitochondrial Transport Proteins 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 electronic resource (476 p.) 311 $a3-0365-3410-5 311 $a3-0365-3409-1 330 $aMitochondrial transporters are membrane-inserted proteins which provide a link between metabolic reactions occurring within the mitochondrial matrix and outside the organelles by catalyzing the translocation of numerous solutes across the mitochondrial membrane. They include the mitochondrial carrier family members, the proteins involved in pyruvate transport, ABC transporters and channels, and are, therefore, essential for many biological processes and cell homeostasis. Identification and functional studies of many mitochondrial transporters have been performed over the years using both in vitro and in vivo systems. The few recently solved structures of these transporters have paved the way for further investigations. Furthermore, alterations in their function are responsible for several diseases. 606 $aResearch & information: general$2bicssc 606 $aBiology, life sciences$2bicssc 610 $ahypoxia 610 $aresistance to hypoxia 610 $amitochondria 610 $amitochondrial calcium transport 610 $amitochondrial calcium uniporter complex 610 $amitochondrial Ca2+-induced permeability transition pore 610 $acyclophilin D 610 $aATP synthase 610 $adisease 610 $aerror of metabolism 610 $amitochondrial carrier 610 $amitochondrial carrier disease 610 $amitochondrial disease 610 $amitochondrial transporter 610 $amembrane transport 610 $amutation 610 $aSLC25. 610 $amitochondrial permeability transition 610 $aapoptosis 610 $anecrosis 610 $aischemia/reperfusion 610 $acancer 610 $aneurodegeneration 610 $acyclosporin A 610 $ametabolite transport 610 $amitochondrial pyruvate carrier 610 $asideroflexin 610 $aTOM 610 $aTIM chaperones 610 $aTIM22 610 $aprotein translocation 610 $amitochondrial biogenesis 610 $aamino acid 610 $abiological function 610 $aion 610 $ainner mitochondrial membrane 610 $amitochondrial carrier family 610 $aorganic acid 610 $asubstrate specificity 610 $atransport mechanism 610 $avitamin 610 $aUSMG5/DAPIT 610 $aglucose-stimulated insulin secretion 610 $aglucose-induced expression 610 $amembrane subunits of ATP synthase 610 $aATP synthase oligomers mitochondrial cristae morphology 610 $ametabolism 610 $ametabolic disorders 610 $aadult-onset type II citrullinemia (CTLN2) 610 $aaspartate/glutamate carrier (AGC) 610 $aanimal model 610 $aargininosuccinate synthetase (ASS) 610 $aaversion to carbohydrates 610 $acitrin 610 $afood taste 610 $aneonatal intrahepatic cholestasis caused by citrin deficiency (NICCD) 610 $aprotein?protein interaction 610 $aMPC 610 $alifespan 610 $apyruvate metabolism 610 $amitochondrial transport 610 $aperoxisomes 610 $acarrier 610 $acofactor 610 $aABC transporter 610 $aaquaporin 610 $aion channels 610 $apotassium channels 610 $aATP 610 $acalcium 610 $aROS 610 $apotassium channel openers 610 $aMCF 610 $afunction 610 $aplant metabolism 610 $aplant development 610 $adiseases 610 $aVDAC1 610 $avirus 610 $apancreatic islets 610 $a?-cell 610 $adiabetes 610 $aglucotoxicity 610 $aglucolipotoxicity 610 $alipotoxicity 610 $amitochondrial carriers 610 $aSLC transporters 610 $aSLC25 610 $aSLC54 610 $aSLC55 610 $aLETM 610 $aSLC56 610 $asequence analysis 610 $aprotein targeting 610 $aVoltage-Dependent Anion selective Channel 610 $aisoforms 610 $aoxidative post-translational modification 610 $agene promoter 610 $ayeast 610 $abioenergetics 610 $aSLC25A1 610 $aCIC 610 $aCTP 610 $acitrate 610 $ainflammation 610 $a22.q11.2 610 $aNAFLD/NASH 610 $acarnitine 610 $acarnitine acyl-carnitine carrier 610 $acarnitine acyl-carnitine translocase 610 $apost-translational modification 610 $asolute carrier family 25 610 $aSLC25A20 610 $aMCU 610 $amitochondrial Ca2+ uniporter 610 $aCa2+ signaling 610 $amitochondrial metabolism 610 $askeletal muscle mitochondria 610 $aSLC25A51 610 $aNAD+ transporters 610 $aNAD 610 $aelectrophysiology 610 $aATP-dependent potassium channel 615 7$aResearch & information: general 615 7$aBiology, life sciences 700 $aPalmieri$b Ferdinando$4edt$091413 702 $aPalmieri$b Ferdinando$4oth 906 $aBOOK 912 $a9910566465303321 996 $aMitochondrial Transport Proteins$93037213 997 $aUNINA