LEADER 03839nam 2201297z- 450 001 9910566461503321 005 20231214133127.0 035 $a(CKB)5680000000037766 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/81115 035 $a(EXLCZ)995680000000037766 100 $a20202205d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aOsteoarthritis: From Molecular Pathways to Therapeutic Advances 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 electronic resource (306 p.) 311 $a3-0365-3464-4 311 $a3-0365-3463-6 330 $aIn this book, we have reported the most recent discoveries and updates regarding molecular pathways in osteoarthritis. In particular, the advances regarding therapeutical options, from a molecular point of view, are largely discussed. 517 $aOsteoarthritis 606 $aResearch & information: general$2bicssc 606 $aBiology, life sciences$2bicssc 610 $aosteoarthritis 610 $acartilage 610 $atype II collagen 610 $amatrix metalloproteinases 610 $aMMP-13 610 $aregulation 610 $ainhibitor 610 $aNO synthase 610 $aInterleukin-1? 610 $achondrocytes 610 $amitochondrial dysfunction 610 $amesenchimal stem cells 610 $achondrocytic commitment 610 $aautophagy 610 $amiRNAs 610 $ahydrostatic pressure 610 $aadipokines 610 $avisfatin 610 $aWnt/?-catenin 610 $amechanical loading 610 $aobesity 610 $amicroRNA 610 $aoxidative stress 610 $avibrational spectroscopy 610 $anear-infrared spectroscopy 610 $ainfrared spectroscopy 610 $aRaman spectroscopy 610 $aearly diagnosis 610 $aexercise 610 $aphysical activity 610 $anutraceuticals 610 $adietary supplements 610 $ainflammation 610 $aaging 610 $ainflammaging 610 $aosteochondral explant culture 610 $ajoint modelling 610 $apharmacological assay 610 $anative tissue analysis 610 $ahexosamine biosynthetic pathway 610 $acartilage trauma 610 $apost-traumatic osteoarthritis 610 $aO-GlcNAcylation 610 $aglucosamine 610 $acell death 610 $atherapy 610 $asex as a biological variable 610 $awhole transcriptome sequencing 610 $amolecules 610 $aTGF-? 610 $aSMAD2/3 signaling 610 $alinker modifications 610 $ameniscus 610 $aproteomics 610 $aMRM 610 $aECM 610 $acelecoxib 610 $aglucosamine sulfate 610 $achondroprotection 610 $aNF-?B 610 $acytokines 610 $achemokines 610 $apathogenesis 610 $abiomarker 610 $achondrocyte 610 $aIL-1? 610 $aIFN?, IL-17 610 $aIL-4 610 $aRNA-Seq 610 $ahypertrophy 610 $aremodeling 610 $aangiogenesis 610 $achondroitin 610 $acollagen 610 $amethylsulfonylmethane 610 $avitamin C 610 $avitamin D 610 $ahyaluronic acid 615 7$aResearch & information: general 615 7$aBiology, life sciences 700 $aVeronese$b Nicola$4edt$0909745 702 $aVeronese$b Nicola$4oth 906 $aBOOK 912 $a9910566461503321 996 $aOsteoarthritis: From Molecular Pathways to Therapeutic Advances$93037272 997 $aUNINA