LEADER 05714oam 22014414a 450 001 9910790678703321 005 20220930214723.0 010 $a0-691-16847-4 010 $a1-4008-4846-6 024 7 $a10.1515/9781400848461 035 $a(CKB)2550000001125726 035 $a(EBL)1329785 035 $a(SSID)ssj0001001028 035 $a(PQKBManifestationID)12394589 035 $a(PQKBTitleCode)TC0001001028 035 $a(PQKBWorkID)10966637 035 $a(PQKB)11448522 035 $a(MiAaPQ)EBC1329785 035 $a(StDuBDS)EDZ0000142002 035 $a(DE-B1597)474190 035 $a(OCoLC)1004867046 035 $a(DE-B1597)9781400848461 035 $a(OCoLC)1273306595 035 $a(MdBmJHUP)musev2_77334 035 $a(PPN)199244251 035 $a(EXLCZ)992550000001125726 100 $a20150921e20162013 uy 0 101 0 $aeng 135 $aur|nu---|u||u 181 $ctxt 182 $cc 183 $acr 200 14$aThe Alzheimer Conundrum$eEntanglements of Dementia and Aging /$fMargaret Lock 205 $aCourse Book 210 1$aPrinceton :$cPrinceton University Press,$d2016. 210 4$dİ2016. 215 $a1 online resource (323 p.) 300 $aOriginally published: 2013. 311 0 $a0-691-14978-X 311 0 $a1-299-95116-3 320 $aIncludes bibliographical references and index. 327 $aAcknowledgments -- Orientations -- Making and remaking Alzheimer disease -- Striving to standardize Alzheimer disease -- Paths to Alzheimer prevention -- Embodied risk made visible -- Alzheimer genes: biomarkers of prediction and prevention -- Genome-wide association studies: back to the future -- Living with embodied omens -- Chance untamed and the return of fate -- Transcending entrenched tensions -- Portraits from the mind -- Notes -- Bibliography -- Index. 330 $aDue to rapidly aging populations, the number of people worldwide experiencing dementia is increasing, and the projections are grim. Despite billions of dollars invested in medical research, no effective treatment has been discovered for Alzheimer's disease, the most common form of dementia. The Alzheimer Conundrum exposes the predicaments embedded in current efforts to slow down or halt Alzheimer's disease through early detection of pre-symptomatic biological changes in healthy individuals. Based on a meticulous account of the history of Alzheimer's disease and extensive in-depth interviews, Margaret Lock highlights the limitations and the dissent associated with biomarker detection. Lock argues that basic research must continue, but should be complemented by a public health approach to prevention that is economically feasible, more humane, and much more effective globally than one exclusively focused on an increasingly harried search for a cure. 606 $aOlder people$xMental health$2fast$3(OCoLC)fst01199117 606 $aBrain$xAging$xMolecular aspects$2fast$3(OCoLC)fst00837576 606 $aAlzheimer's disease$xAge factors$2fast$3(OCoLC)fst01750368 606 $aBrain$xAging$xMolecular aspects 606 $aOlder people$xMental health 606 $aAlzheimer's disease$xAge factors 610 $aAPOE. 610 $aAlois Alzheimer. 610 $aAlzheimer disease. 610 $aAlzheimer enterprise. 610 $aAlzheimer genetics. 610 $aAlzheimer prevention. 610 $aAlzheimer world. 610 $aAlzheimer's disease. 610 $aDNA samples. 610 $aDNA. 610 $aGWAS. 610 $aHuntington disease. 610 $aaging population. 610 $aaging populations. 610 $aaging societies. 610 $aamyloid cascade hypothesis. 610 $aamyloid cascade process. 610 $abehavioral changes. 610 $abiomarkers. 610 $abiosociality. 610 $abreast cancer. 610 $aclinical diagnosis. 610 $aclinical settings. 610 $acontrol samples. 610 $adementia. 610 $adiagnosis. 610 $adivination. 610 $aearly-onset. 610 $aenvironmental variables. 610 $aepidemiological research. 610 $aepidemiology. 610 $aepigenetics. 610 $aethnographic research. 610 $aexpert knowledge. 610 $afamily practice settings. 610 $agene function. 610 $agenes. 610 $agenetic testing. 610 $ageneticization. 610 $agenome-wide association studies. 610 $agenomics. 610 $aglobal economy. 610 $alate-onset. 610 $alocalization theory. 610 $amedical publications. 610 $amemory clinics. 610 $amemory loss. 610 $amicro-medical management. 610 $amild cognitive impairment. 610 $amolecular approach. 610 $amolecular biologists. 610 $amolecularization. 610 $aneuritic amyloid plaques. 610 $aneurofibrillary tangles. 610 $aneuroimaging. 610 $aprevention. 610 $aprodromal. 610 $apublic health. 610 $aresearch. 610 $athroughput technology. 615 7$aOlder people$xMental health. 615 7$aBrain$xAging$xMolecular aspects. 615 7$aAlzheimer's disease$xAge factors. 615 0$aBrain$xAging$xMolecular aspects. 615 0$aOlder people$xMental health. 615 0$aAlzheimer's disease$xAge factors. 676 $a362.1968/31 700 $aLock$b Margaret M.$01009391 801 0$bMdBmJHUP 801 1$bMdBmJHUP 906 $aBOOK 912 $a9910790678703321 996 $aThe Alzheimer Conundrum$93710283 997 $aUNINA LEADER 03286nam 2200721z- 450 001 9910557788403321 005 20210501 035 $a(CKB)5400000000045504 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/68990 035 $a(oapen)doab68990 035 $a(EXLCZ)995400000000045504 100 $a20202105d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aEngineering Metamaterials 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 online resource (108 p.) 311 08$a3-03936-922-9 311 08$a3-03936-923-7 330 $aA couple of decades have passed since the advent of electromagnetic metamaterials. Although the research on artificial microwave materials dates back to the middle of the 20th century, the most prominent development in the electromagnetics of artificial media has happened in the new millennium. In the last decade, the electromagnetics of one-, two-, and three-dimensional metamaterials acquired robust characterization and design tools. Novel fabrication techniques have been developed. Many exotic effects involving metamaterials and metasurfaces, which initially belonged in a scientist's lab, are now well understood by practicing engineers. Therefore, it is the right time for the metamaterial concepts to become a designer's tools of choice in the landscape of electronics, microwaves, and photonics. Answering such a demand, the book "Engineering Metamaterials" focuses on the theory and applications of electromagnetic metamaterials, metasurfaces, and metamaterial transmission lines as the building blocks of present-day and future electronic, photonic, and microwave devices. 606 $aHistory of engineering and technology$2bicssc 610 $aactive control 610 $acommon-mode noise 610 $acorrugated ground plane 610 $adifferential signaling 610 $adual-band 610 $adual-band polarization converters 610 $aelectromagnetic bandgap 610 $aelectromagnetic distortion 610 $aencoder 610 $aepsilon-negative material 610 $aevanescent field tunneling 610 $afractals 610 $agraphene 610 $aleft-handed line 610 $alinear to circular polarization converter 610 $ametal hole arrays (MHA) 610 $ametamaterial 610 $ametamaterials 610 $ametasurfaces 610 $amicrowave absorbers 610 $amu-negative material 610 $an/a 610 $aphase shift 610 $asensors 610 $asplit-ring-resonators 610 $aspoof surface plasmon polariton (SSPP) 610 $astepped impedance 610 $aterahertz metamaterials 610 $atransmission-based polarization conversion 610 $atwo-dimensional imaging 610 $aUHF-RFID 610 $awaveguides 615 7$aHistory of engineering and technology 700 $aMaslovski$b Stanislav$4edt$01313392 702 $aMaslovski$b Stanislav$4oth 906 $aBOOK 912 $a9910557788403321 996 $aEngineering Metamaterials$93031374 997 $aUNINA