LEADER 00872nam0-22003251i-450- 001 990008045140403321 005 20080702110555.0 010 $a0415169127 035 $a000804514 035 $aFED01000804514 035 $a(Aleph)000804514FED01 035 $a000804514 100 $a20050412d1998----km-y0itay50------ba 101 0 $aita 102 $aIT 200 1 $a<>language of humour$fAlison Ross 210 $aLondon ; New York$cRoutledge$d1998 215 $aX, 118 p.$d25 cm 225 1 $aIntertext 610 0 $aLetteratura umoristica inglese 676 $a827.009$v21$zita 700 1$aRoss,$bAlison$0497331 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990008045140403321 952 $aXV Ib 575$b43413$fFSPBC 952 $aXV Ib 550$b41608$fFSPBC 959 $aFSPBC 996 $aLanguage of humour$9752830 997 $aUNINA LEADER 04522nam 22006974a 450 001 9911019704803321 005 20200520144314.0 010 $a9786610274062 010 $a9781280274060 010 $a1280274069 010 $a9780470871614 010 $a047087161X 010 $a9780470871621 010 $a0470871628 035 $a(CKB)111087027098534 035 $a(EBL)219736 035 $a(SSID)ssj0000161463 035 $a(PQKBManifestationID)11183409 035 $a(PQKBTitleCode)TC0000161463 035 $a(PQKBWorkID)10199258 035 $a(PQKB)10363702 035 $a(MiAaPQ)EBC219736 035 $a(OCoLC)54511024 035 $a(Perlego)2760826 035 $a(EXLCZ)99111087027098534 100 $a20030724d2003 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aGeneration and effector functions of regulatory lymphocytes /$f[editors, Gregory Bock and Jamie Goode] 210 $aHoboken, N.J. $cWiley$dc2003 215 $a1 online resource (327 p.) 225 1 $aNovartis Foundation symposium ;$v252 300 $aDescription based upon print version of record. 311 08$a9780470850749 311 08$a0470850744 320 $aIncludes bibliographical references and index. 327 $aGENERATION AND EFFECTOR FUNCTIONS OF REGULATORY LYMPHOCYTES; Contents; Participants; Chair's introduction; Thymic generation and selection of CD25(+)CD4(+) regulatory T cells: implications of their broad repertoire and high self-reactivity for the maintenance of immunological self-tolerance; Discussion; Control of T cell activation by CD4(+)CD25(+) suppressor T cells; Discussion; Regulation of experimental autoimmune encephalomyelitis (EAE) by CD4(+)CD25(+) regulatory T cells; Discussion; The role of CD28 and CTLA4 in the function and homeostasis of CD4(+)CD25(+) regulatory T cells 327 $aDiscussionCD4(+)CD25(+) regulatory cells from human peripheral blood express very high levels of CD25 ex vivo; Discussion; Control of immune pathology by regulatory T cells; Discussion; General discussion I TGFB; Type 1 T regulatory cells and their relationship with CD4(+)CD25(+) T regulatory cells; Discussion; (PRO)insulin-specific regulatory T cells; Discussion; CD1d-restricted NKT regulatory cells: functional genomic analyses provide new insights into the mechanisms of protection against Type 1 diabetes; Discussion 327 $aSeven surprises in the TCR-centred regulation of immune responsiveness in an autoimmune systemDiscussion; Regulatory cells in transplantation; Discussion; CD4(+) regulatory T cells in chronic viral infection; Discussion; General discussion II; Modulation of T cell responses after cross-talk between antigen presenting cells and T cells: a give-and-take relationship; Discussion; Dendritic cells: controllers of the immune system and a new promise for immunotherapy; Discussion; Regulation of viral and autoimmune responses; Discussion; General discussion III Active immune regulation 327 $aNotch signalling in the peripheral immune systemDiscussion; CD3 antibody treatment stimulates the functional capability of regulatory T cells; Discussion; The role of dendritic cells in regulating mucosal immunity and tolerance; Discussion; Index of contributors; Subject index 330 $aOver the last several years, immunologists have re-discovered the importance of regulatory lymphocytes, formerly termed 'suppressor cells'. Many recent reports have documented their existence, effector functions and potential therapeutic benefits in autoimmunity and transplantation. However, even though modern techniques have allowed us to get a much more detailed picture of these cells, they are still highly controversial. Several unresolved issues responsible for this dilemma are discussed in this book: it is difficult to grow and clone such cells, their phenotypes and effector functions are 410 0$aNovartis Foundation symposium ;$v252. 606 $aLymphocytes 606 $aT cells 606 $aImmune response$xRegulation 615 0$aLymphocytes. 615 0$aT cells. 615 0$aImmune response$xRegulation. 676 $a571.9/6 701 $aBock$b Gregory$0322650 701 $aGoode$b Jamie$0283336 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911019704803321 996 $aGeneration and effector functions of regulatory lymphocytes$94417569 997 $aUNINA LEADER 07558nam 2202185z- 450 001 9910557785803321 005 20220111 035 $a(CKB)5400000000045530 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/76752 035 $a(oapen)doab76752 035 $a(oapen)76752 035 $a(EXLCZ)995400000000045530 100 $a20202201d2021 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aCFD Based Researches and Applications for Fluid Machinery and Fluid Device 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021 215 $a1 online resource (539 p.) 311 08$a3-0365-1816-9 311 08$a3-0365-1815-0 330 $aThe demand for computational fluid dynamics (CFD)-based numerical techniques is increasing rapidly with the development of the computing power system. These advanced CFD techniques are applicable to various issues in the industrial engineering fields and especially contribute to the design of fluid machinery and fluid devices, which have very complicated unsteady flow phenomena and physics. In other words, to aid the rapid development of CFD techniques, the performances of fluid machinery and fluid devices with complicated unsteady flows have been enhanced significantly. In addition, many persistently troublesome problems of fluid machinery and fluid devices such as flow instability, rotor-stator interaction, surging, cavitation, vibration, and noise are solved clearly using advanced CFD techniques.This Special Issue on "CFD-Based Research and Applications for Fluid Machinery and Fluid Devices" aims to present recent novel research trends based on advanced CFD techniques for fluid machinery and fluid devices. The following topics, among others, are included in this issue:- CFD techniques and applications in fluid machinery and fluid devices;- Unsteady and transient phenomena in fluid machinery and fluid devices;- Pumps, fans, compressors, hydraulic turbines, pump turbines, valves, etc. 606 $aTechnology: general issues$2bicssc 610 $aadiabatic film-cooling effectiveness 610 $aaerodynamic 610 $aaerodynamic performance 610 $aartificial neural networks (ANN) 610 $aaxial compressor 610 $aaxial fan 610 $aaxial-flow pump 610 $ablade outlet angle 610 $ablowing ratio 610 $acascade 610 $acavitating flow and instabilities 610 $acavitation performance 610 $acell-set model 610 $acentrifugal fan 610 $acentrifugal pump 610 $aCFD 610 $acharacteristic implicit method 610 $aclearance 610 $acomputational fluid dynamics 610 $acomputational fluid dynamics (CFD) 610 $aComputational Fluid Dynamics (CFD) 610 $adeflection angle of the flap (?F) 610 $adesign 610 $adesign factors 610 $adiffuser 610 $adouble suction 610 $adouble-suction impeller 610 $adynamic characteristics 610 $adynamic stress 610 $aenergy characteristics 610 $aenergy dissipation 610 $aenergy recovery 610 $aentropy production 610 $aextrusion fault 610 $afigure of merit 610 $afilm cooling 610 $afish farm 610 $afixed flow passage 610 $aflow field 610 $aflow function 610 $aflow similarity 610 $aflow uniformity 610 $afluent 610 $aFrancis turbine 610 $afriction factor 610 $afrozen rotor 610 $afull factorial methods 610 $agas turbine 610 $agroove 610 $aheat transfer performance 610 $ahover 610 $ahydraulic losses 610 $aimpeller 610 $aincidence angle 610 $ainducer 610 $ainducer-type guide vane 610 $ainternal flow 610 $ainverse design method 610 $ajet 610 $alaminar flow 610 $alarge eddy simulation 610 $alateral cavity 610 $aleakage 610 $aleakage rate 610 $aLES 610 $aLHS 610 $aliquid film 610 $amachine learning 610 $amatching optimization 610 $amechanical seal 610 $amicrochannel heat sink 610 $amixing 610 $amulti-condition optimization 610 $amulti-objective optimization 610 $amultistage centrifugal pump 610 $an/a 610 $anegative pressure 610 $anet positive suction head (NPSH) 610 $anoise 610 $anoise characteristics 610 $anumerical simulation 610 $aNusselt number 610 $aoctorotor SUAV 610 $aopen-design 610 $aoptimization 610 $aoptimization control 610 $aoptimum model 610 $aparameterization 610 $apartial similarity principle 610 $aperformance test 610 $apitched blade turbine 610 $aplane cascade design 610 $apower coefficient 610 $apower consumption 610 $apressure fluctuation 610 $apressure ratio 610 $aproper orthogonal decomposition 610 $aPSO-MVFSA 610 $apump as turbine 610 $apump-turbine 610 $aRANS 610 $areactor coolant pump (RCP) 610 $arelative roughness 610 $areversible 610 $aReynolds-averaged Navier-Stokes (RANS) 610 $aReynolds-averaged Navier-Stokes equations 610 $aribs 610 $aroot clearance radius 610 $arotor spacing 610 $asealing performance 610 $ashape optimization 610 $aSirocco fan 610 $asmall hydropower 610 $asolar air heater 610 $asound pressure 610 $aspiral flow 610 $astability improvement 610 $astart-up process 610 $astartup period 610 $astep casing 610 $astepped labyrinth seal 610 $athe mixed free-surface-pressurized flow 610 $athrust 610 $athrust coefficient 610 $atip clearance 610 $atrailing edge flap (TEF) 610 $atrailing edge flap with Micro-Tab 610 $atransient characteristics 610 $atriple holes 610 $atubular turbine 610 $atwin-volute 610 $atwo-vane pump 610 $aUAV 610 $aURANS 610 $avarying pitch 610 $avent holes 610 $avolute tongue radius 610 $avortex 610 $avortex generator (VG) 610 $avortex pump 610 $avortices distribution 610 $awaviness 610 $awavy microchannel 615 7$aTechnology: general issues 700 $aKim$b Jin-Hyuk$4edt$01299457 702 $aKim$b Sung-Min$4edt 702 $aChoi$b Minsuk$4edt 702 $aTan$b Lei$4edt 702 $aHuang$b Bin$4edt 702 $aPei$b Ji$4edt 702 $aKim$b Jin-Hyuk$4oth 702 $aKim$b Sung-Min$4oth 702 $aChoi$b Minsuk$4oth 702 $aTan$b Lei$4oth 702 $aHuang$b Bin$4oth 702 $aPei$b Ji$4oth 906 $aBOOK 912 $a9910557785803321 996 $aCFD Based Researches and Applications for Fluid Machinery and Fluid Device$93025188 997 $aUNINA