LEADER 00963cam0 22002533 450 001 TWSOB00001333 005 20150714102448.0 100 $a20040115d1973 |||||ita|0103 ba 101 $afra 102 $aFR 200 1 $a<>œuvre romanesque de Matilde Serao$fM. G. Martin-Gistucci$gpublié avec l'aide du Centre Universitaire de Savoie 210 $aGrenoble$cPresses Universitaries$d1973 215 $a664 p.$d24 cm 700 1$aMartin[-]Gistucci$b, Marie_Gracieuse$3AF00014861$4070$0311944 712 02$a*Centre Universitaire de Savoie$3SOBA00011365$4070 801 0$aIT$bUNISOB$c20150714$gRICA 850 $aUNISOB 852 $aUNISOB$j850$m18290 912 $aTWSOB00001333 940 $aM 102 Monografia moderna SBN 941 $aM 957 $a850$b000570$gSI$d18290$rACQUISTO$1rovito$2UNISOB$3UNISOB$420150714102130.0$520150714102141.0$6rovito 996 $aUvre romanesque de Matilde Seraouvre romanesque de Matilde Serao$91672811 997 $aUNISOB LEADER 04519nam 2201069z- 450 001 9910557781603321 005 20220111 035 $a(CKB)5400000000045573 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/76798 035 $a(oapen)doab76798 035 $a(EXLCZ)995400000000045573 100 $a20202201d2021 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMultimodal Therapy of Upper Gastrointestinal Malignancies 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021 215 $a1 online resource (272 p.) 311 08$a3-0365-0920-8 311 08$a3-0365-0921-6 330 $aRecent decades have seen remarkable advances in the treatment of upper gastrointestinal malignancies, i.e., adenocarcinoma and squamous cell carcinoma as well as gastrointestinal stromal and other rare tumors of the esophagus and stomach. While, historically, surgical resection has been the sole treatment for these tumors, multimodal therapies have meanwhile proven their efficacy. At present, pre- and postoperative chemotherapy and radiotherapy, targeted drug therapy, and stage-specific surgical approaches are all indispensable cornerstones of an individualized treatment for upper gastrointestinal malignancies. With such multimodal treatment, better outcomes comprising improved quality of life and prolonged survival have been achieved for patients. However, for many tumor entities and stages, the ideal combination and sequence of treatments is still being evaluated in clinical trials. Moreover, the value of novel approaches such as immunotherapy or robotic surgery remains a matter of research. In this Special Issue of Cancers, up-to-date original research, short communications, and comprehensive review articles on all modalities playing a role in the treatment of upper gastrointestinal malignancies have been published. 606 $aPublic health and preventive medicine$2bicssc 610 $aadjuvant therapy 610 $aBarrett's esophagus 610 $acancer dormancy 610 $achemo-radiotherapy 610 $aclinical pathways 610 $acomplications 610 $aconversion surgery 610 $adefinitive chemoradiotherapy 610 $aearly adenocarcinoma of esophagus 610 $aendoscopic mucosal resection 610 $aendoscopic submucosal dissection 610 $aesophageal anastomosis 610 $aesophageal cancer 610 $aesophageal squamous cell carcinoma 610 $aesophagectomy 610 $afailure to rescue 610 $agastrectomy 610 $agastric cancer 610 $agastric surgery 610 $agastric/gastroesophageal cancer 610 $agastro-esophageal reflux disease 610 $agastrointestinal stromal tumor 610 $agastrointestinal tract 610 $agenetic diagnosis 610 $agenetics 610 $aGIST 610 $aimatinib 610 $aimmunotherapy 610 $ainduction chemotherapy 610 $aLauren histotype 610 $alymph node ratio 610 $aMALT lymphoma 610 $aminimally invasive surgery 610 $amortality 610 $amucosal resection 610 $amultidisciplinary 610 $amultimodal treatment 610 $an/a 610 $aneoadjuvant chemoradiotherapy 610 $aneoadjuvant chemotherapy 610 $aneoadjuvant therapy 610 $aneoadjuvant treatment 610 $aneuroendocrine tumor 610 $anuclear receptor NR2F1 610 $anutritional status 610 $aoncological gastrectomy 610 $aorgan preservation 610 $aoutcome 610 $aoutcomes 610 $aoverall survival 610 $aperioperative chemotherapy 610 $aquality of care 610 $aradiosensitivity 610 $arelapse-free survival 610 $asarcopenia 610 $askeletal muscle index 610 $asquamous cell esophageal cancer 610 $astandardization 610 $astomach 610 $asubmucosal dissection 610 $asurvival 615 7$aPublic health and preventive medicine 700 $aRonellenfitsch$b Ulrich$4edt$01309877 702 $aRonellenfitsch$b Ulrich$4oth 906 $aBOOK 912 $a9910557781603321 996 $aMultimodal Therapy of Upper Gastrointestinal Malignancies$93029691 997 $aUNINA