LEADER 03426nam  2200637z- 450 
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035   $a(CKB)5400000000045596
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/76756
035   $a(EXLCZ)995400000000045596
100   $a20202201d2021      |y             0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aGenome Mining and Synthetic Biology in Marine Natural Products Discovery
210   $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021
215   $a1 electronic resource (92 p.)
311   $a3-0365-0254-8 
311   $a3-0365-0255-6 
330   $aIn recent years, marine genomics has become a growning rapidly field, helped by the large amount of information that is becoming available to the international scientific community. Taking into account the current excitement in the field of marine biotechnology, this Special Issue entitled ?Genome Mining and Synthetic Biology in Marine Natural Product Discovery? aims to to assess the impact of these molecular approaches on the discovery of bioactive compounds from marine organisms. The term ?genome mining? is used to identify all bioinformatic investigations aimed at detecting the biosynthetic pathways of bioactive natural products and their possible functional and chemical interactions. Several studies are now reporting on marine organisms. Oceans cover nearly 70% of the Earth?s surface and host a huge ecological, chemical, and biological diversity. The natural conditions of the sea favor, in marine organisms, the production of a large variety of novel molecules with great pharmaceutical potential. Marine organisms are unique in their structural and functional features compared to terrestrial ones. Innovation in this field is very rapid, as revealed by the funding of several Seventh Framework Programme (FP7) and Horizon 2020 projects under the topic ?Blue Growth?, with the urgent goal of discovering new drugs.
606   $aTechnology: general issues$2bicssc
610   $agenome mining
610   $aglobal regulator
610   $aLaeA
610   $aoverexpression
610   $aPenicillium dipodomyis
610   $asorbicillinoids
610   $aulvan-derived oligosaccharides
610   $aulvan lyase
610   $aheterologous expression
610   $apolysaccharide lyase family 25
610   $awhole-genome sequencing
610   $adocosahexaenoic acid (DHA)
610   $apolyunsaturated fatty acid
610   $afatty acid synthesis pathway
610   $apolyketide synthase pathway
610   $abacteria
610   $afungi
610   $anatural products
610   $asynthetic biology
610   $amicroalgae
610   $amonogalactosyldiacylglycerol synthase
610   $aUDP-sulfoquinovose synthase
610   $asulfoquinovosyltransferase
610   $amonogalactosyldiacylglycerols
610   $asulfoquinovosyldiacylglycerols
610   $atranscriptome analysis
615  7$aTechnology: general issues
700   $aCostantini$b Maria$4edt$0738492
702   $aCostantini$b Maria$4oth
906   $aBOOK
912   $a9910557779303321
996   $aGenome Mining and Synthetic Biology in Marine Natural Products Discovery$93033835
997   $aUNINA