LEADER 03449nam 2200697z- 450 001 9910557779003321 005 20231214133600.0 035 $a(CKB)5400000000045599 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/76379 035 $a(EXLCZ)995400000000045599 100 $a20202201d2021 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAsymmetry in Biological Homochirality 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021 215 $a1 electronic resource (102 p.) 311 $a3-0365-0442-7 330 $aChirality, or handedness, is a fundamental physical characteristic, which spans the length scales ranging from elementary particles to the chiral asymmetry of spiral galaxies. The way in which chirality in chemistry, or molecular handedness, may have emerged in a primitive terrestrial environment, and how it can be triggered, amplified, and transferred, are deeply challenging problems rooted in both fundamental scientific interests and the technological potentials for science and society. Chirality constitutes a unifying feature of the living world and is a prime driving force for molecular selection and genetic evolution in biology. In this book, we offer a selection of five distinct approaches to this problem by leading experts in the field. The selected topics range from protein chirality and its relevance to protein ageing, protein aggregation and neurodegeneration, entropy production associated with chiral symmetry breaking in closed systems, chiral oscillations in polymerization models involving higher-order oligomers, the mirror symmetry breaking in liquids and its implications for the development of homochirality in abiogenesis, the role of chirality in the chemical sciences, and some philosophical implications of chirality. 606 $aResearch & information: general$2bicssc 610 $abiochirality 610 $apost-translational modifications 610 $aprotein folding 610 $aprotein aggregation 610 $aspontaneous chemical reactions 610 $aneurodegeneration 610 $anon-equilibrium phase transitions 610 $achiral symmetry breaking 610 $aentropy production 610 $aclosed systems 610 $anonequilibrium 610 $adissipative structures 610 $amirror symmetry breaking 610 $abiological chirality 610 $aliquid crystals 610 $aproto-RNA 610 $anetworks 610 $acompartmentalization 610 $achiral liquids 610 $acubic phases 610 $aprebiotic chemistry 610 $achirality amplification 610 $ahelical self-assembly 610 $achiral oscillations 610 $aspontaneous mirror symmetry breaking 610 $aorigin of homochirality 610 $aabsolute asymmetric synthesis 610 $abiological homochirality 610 $achemical abiotic evolution 610 $achirality 610 $aorigin of life 610 $adissipative reaction systems 615 7$aResearch & information: general 700 $aHochberg$b David$4edt$01331611 702 $aHochberg$b David$4oth 906 $aBOOK 912 $a9910557779003321 996 $aAsymmetry in Biological Homochirality$93040494 997 $aUNINA