LEADER 03561nam 2201033z- 450 001 9910557769003321 005 20231214132937.0 035 $a(CKB)5400000000045671 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/77086 035 $a(EXLCZ)995400000000045671 100 $a20202201d2021 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aIntegrative Multi-Omics in Biomedical Research 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021 215 $a1 electronic resource (178 p.) 311 $a3-0365-2582-3 311 $a3-0365-2583-1 330 $aGenomics technologies revolutionised biomedicine research, but the genome alone is not sufficient to capture biological complexity. Postgenomic methods, typically based on mass spectrometry, comprise the analysis of metabolites, lipids, and proteins and are an essential complement to genomics and transcriptomics. Multidimensional omics is becoming established to provide accurate and comprehensive state descriptions. This book covers the latest methodological developments for, and applications of integrative multi-omics in biomedical research. 606 $aResearch & information: general$2bicssc 606 $aBiology, life sciences$2bicssc 610 $atarget identification 610 $atarget validation 610 $alabel-free method for drugs 610 $aanti-angiogenesis 610 $amechanism of action 610 $areceptor tyrosine kinases 610 $acurcumin 610 $anatural products 610 $alipid 610 $alipidomics 610 $acardiac metaplasia 610 $aBarrett's esophagus 610 $aesophageal adenocarcinoma 610 $amicrobiota 610 $aDNA sensing 610 $aIFI16 610 $acGAS 610 $ainnate immunity 610 $aprotein interactions 610 $avirus-host interactions 610 $apost-translational modifications 610 $amass spectrometry 610 $aproteomics 610 $atranscriptomics 610 $amulti-omics 610 $amulti-omics analysis 610 $astudy design 610 $abioinformatics 610 $amachine learning 610 $aanalysis flow 610 $ametabolomics 610 $aplanned myocardial infarction (PMI) 610 $amyocardial infarction (MI) 610 $aexercise 610 $aheart 610 $acheminformatics 610 $abatch variations 610 $aeicosanoids 610 $afetal calf serum 610 $aperoxisomes 610 $ahost-pathogen interactions 610 $asecretome 610 $amacrophages 610 $aacute myeloid leukemia 610 $aHL-60 cell line 610 $aATRA 610 $ainduced differentiation 610 $atranscriptome 610 $aproteome 610 $atranscription factors 610 $akey molecules 610 $aregulatory pathway modelling 610 $aSRM 610 $aendometriosis 610 $ainflammation 615 7$aResearch & information: general 615 7$aBiology, life sciences 700 $aGerner$b Christopher$4edt$01309872 702 $aHill$b Michelle$4edt 702 $aGerner$b Christopher$4oth 702 $aHill$b Michelle$4oth 906 $aBOOK 912 $a9910557769003321 996 $aIntegrative Multi-Omics in Biomedical Research$93029686 997 $aUNINA