LEADER 03882nam 2201189z- 450 001 9910557768503321 005 20231214133410.0 035 $a(CKB)5400000000045676 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/76720 035 $a(EXLCZ)995400000000045676 100 $a20202201d2021 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aRecent Developments in Cancer Systems Biology 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021 215 $a1 electronic resource (272 p.) 311 $a3-0365-1472-4 311 $a3-0365-1471-6 330 $aThis ebook includes original research articles and reviews to update readers on the state of the art systems approach to not only discover novel diagnostic and prognostic biomarkers for several cancer types, but also evaluate methodologies to map out important genomic signatures. In addition, therapeutic targets and drug repurposing have been emphasized for a variety of cancer types. In particular, new and established researchers who desire to learn about cancer systems biology and why it is possibly the leading front to a personalized medicine approach will enjoy reading this book. 606 $aMedicine$2bicssc 610 $aSestrin2 610 $alung cancer 610 $aknockdown 610 $acancer progression 610 $abioinformatics 610 $apatient survival 610 $alung adenocarcinoma 610 $acirculating miR-1246 610 $aglycosaminoglycan binding 610 $aprognosis 610 $aPI3K-Akt signaling pathways 610 $aTargetScan 610 $aUBE2C 610 $acancer systems biology 610 $aexperimental model systems 610 $anext-generation sequencing 610 $asingle-cell sequencing 610 $apatient-derived xenografts 610 $apatient-derived organoids 610 $atriple-negative breast cancer 610 $apersonalized medicine 610 $acomputational methods 610 $adrug repurposing 610 $aclinical trials 610 $acancer stem cells 610 $aETS 610 $aElk-1 610 $astem cell 610 $amicroarray 610 $abrain-tumor-initiating cell (BTIC) 610 $apancreatic cancer 610 $asystems biology 610 $aomics 610 $abiomarker 610 $agenomics 610 $atranscriptomics 610 $aproteomics 610 $ametabolomics 610 $aglycomics 610 $ametagenomics 610 $aEts 610 $aPEA3 610 $aEts-1 610 $aglioma 610 $aoptical genome mapping 610 $asolid tumors 610 $acancer genomics 610 $abreast 610 $aovarian 610 $acancer 610 $aTCGA 610 $anon-small-cell lung cancer 610 $alung adenocarcinoma (LUAD) 610 $alung squamous cell carcinoma (LUSC) 610 $adifferential expression 610 $aSNV 610 $aCNV 610 $arisk group 610 $asignature 610 $asurvival 610 $arenal cancers 610 $aprotein interactome 610 $adiagnostic biomarker 610 $aprognostic biomarker 610 $avirtual screening 610 $adocking 610 $aacute myeloid leukemia 610 $aBoolean model 610 $adrug resistance 610 $anetwork 615 7$aMedicine 700 $aSinha$b Raghu$4edt$01297573 702 $aArga$b Kazim Yalcin$4edt 702 $aSinha$b Raghu$4oth 702 $aArga$b Kazim Yalcin$4oth 906 $aBOOK 912 $a9910557768503321 996 $aRecent Developments in Cancer Systems Biology$93024564 997 $aUNINA