LEADER 03981nam  2201033z- 450 
001 9910557746903321
005 20231214133701.0
035   $a(CKB)5400000000045873
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/76537
035   $a(EXLCZ)995400000000045873
100   $a20202201d2021      |y             0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aIntrinsically Disordered Proteins and Chronic Diseases
210   $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021
215   $a1 electronic resource (224 p.)
311   $a3-0365-1262-4 
311   $a3-0365-1263-2 
330   $aThis book is an embodiment of a series of articles that were published as part of a Special Issue of Biomolecules. It is dedicated to exploring the role of intrinsically disordered proteins (IDPs) in various chronic diseases. The main goal of the articles is to describe recent progress in elucidating the mechanisms by which IDPs cause various human diseases, such as cancer, cardiovascular disease, amyloidosis, neurodegenerative diseases, diabetes, and genetic diseases, to name a few. Contributed by leading investigators in the field, this compendium serves as a valuable resource for researchers, clinicians as well as postdoctoral fellows and graduate students
606   $aResearch & information: general$2bicssc
610   $aIDP
610   $afuzzy interactions
610   $aprotein complementation assays
610   $asplit-GFP reassembly
610   $akinetics
610   $amembraneless organelles
610   $aoptical tweezer
610   $aliquid-liquid phase separation
610   $aprotein diffusion
610   $adepletion interaction
610   $aentropic force
610   $alow-complexity sequences
610   $aintrinsically disordered proteins
610   $aPAGE4
610   $aconformational plasticity
610   $aorder-disorder transition
610   $aphosphorylation
610   $aintrinsic disordered protein
610   $aextremely fuzzy complex
610   $aprotein interaction
610   $abinding mechanism
610   $atumor protein p53
610   $amouse double minute 2
610   $amouse double minute 4
610   $aKinase-inducible domain interacting domain
610   $aphosphomimetics
610   $anuclear magnetic resonance
610   $atransient secondary structure
610   $aCOR15A
610   $aLate embryogenesis abundant
610   $aTrifluoroethanol
610   $aNuclear magnetic resonance
610   $aintrinsically disordered regions
610   $afunctional segments
610   $adisease-related proteins
610   $aprotein-protein interaction
610   $asubcellular location
610   $aglucocorticoid receptor
610   $aintrinsically disordered
610   $atransactivation activity
610   $agene regulation
610   $acoactivators
610   $amicrotubule associated protein
610   $atau
610   $aintrinsically disordered protein
610   $adynamic configuration
610   $afree energy landscape
610   $amicrotubules
610   $aelectrostatics
610   $adiffusion
610   $aprotein structure prediction
610   $amolecular modelling
610   $amolecular dynamics
610   $atau-microtubule association
610   $aconformational ensemble
610   $areplica exchange molecular dynamics
610   $adrug design
615  7$aResearch & information: general
700   $aKulkarni$b Prakash$4edt$01299454
702   $aUversky$b Vladimir N$4edt
702   $aKulkarni$b Prakash$4oth
702   $aUversky$b Vladimir N$4oth
906   $aBOOK
912   $a9910557746903321
996   $aIntrinsically Disordered Proteins and Chronic Diseases$93025182
997   $aUNINA